Older persons care & Learning Disability Flashcards
TOPICS COVERED: Falls Pressure ulcers Polypharmacy Continence Frailty Dementia Delirium Capacity and Best Interest Decision making Community hospitals/ care Nutrition Advance care planning Learning disability
What are the key things to estabilish in a history of a fall?
- What were they doing?
- How did the fall happen?
- How did they feel before the fall?
- Any dizziness or lightheaded feelings?
- Loss of consciousness?
- Cardiac symptoms?
- Weakness?
- Has this happened previously?
- Any witnesses
- Medications- sedatives, cardiac meds, anticholinergics, hypoglycaemics, opiates
- How do they normally mobilise?
What does normal gait involve?
- Neurological system- basal ganglia & cortical basal ganglia loop
- MSK system- tone & strength
- Effective processing of senses- sight, sound, sensation (fine touch & proprioception)
What factors may predispose patients to fall?
- Hx of falls = strongest risk factor
- Conditions affecting mobility or balance: arthritis, diabetes, incontinence, stroke, syncope, Parkinson’s
- Postural hypotension
- Polypharmacy (4+ medications)
- Psychoactive drugs (benzos)
- Drugs causing postural hypotension (anti-hypertensives)
- Home hazards- loose rugs, mats, poor lighting, wet surfaces eg in bathroom, loose fitting eg handrails
How can psychological state increase falls risk status?
- Anxiety:
- Gait- individuals taking shorter strides and having slower gait speed
- Pts may focus more internally (own feet) rather than externally increasing falls risk
- Depression
- Isolated symptoms of depression can have a direct role in promoting falls in the elderly- insomnia, poor appetite, weight loss
- Associated cognitive deficits- affecting attention, executive function, processing speed
What medications can predispose patients to fall?
- Drugs causing sedation, with slowing of reaction times and impaired balance, such as:
- Benzodiazepines
- Zopiclone
- Amitriptyline
- MAO inhibitors
- Drugs for psychosis- chlorpromazine, haloperidol
- SSRIs
- Anti-epileptics- phenytoin
- Carbamazepine
- Vestibular sedatives- prochlorperazine
- Sedating antihistamines- chlorphenamine, promethazine
- Anticholinergics acting on bladder- oxybutynin
- Drugs acting on the heart & circulation, causing hypotension
- ACEi, ARBs
- Thiazide & loop diuretics
- Beta blockers
- CCBs- amlodipine, nifedipine
- Ach esterase inhibitors (for dementia)- donepezil, rivastigmine- may cause bradycardia & syncope
How to assess someone’s risk of a fall?
- Assess hx of falls
- Assess gait, balance and mobility, muscle weakness
- Osteoporosis risk
- Visual impairment
- Cognitive, neurological, cardiovascular problems
- Urinary incontinence
- Home hazards
- Polypharmacy & the use of drugs that increase the risk of falling
- Perceived impaired functional ability and fear relating to falling
How do you perform a focused clinical assessment in someone who has fallen?
- Cardiovascular examination – include an ECG and a lying and standing BP (at immediate, 3 and 5 mins)
- Neurological examination
- MSK examination – assess their joints
- Gait assessment- – how do they mobilise, what with and what is their gait like
How do you perform & interpret a lying and standing blood pressure?
- Measure blood pressure supine or sitting
- Measure blood pressure after standing for 3 minutes
- A fall of >20 systolic or > 10 mmHg diastolic BP = postural hypotension
- Take heart rate as well-
- A normal rise in HR accompanying the fall in BP is typical of pts with depletion of intravascular volume (dehydration or haemorrhage) or impaired vasoconstrictor tone (usually caused by drugs)
- Expect tachycardia in response to hypotension to be blunted when there is an underlying neurogenic cause (eg peripheral neuropathy)
Define postural hypotension?
- Also called orthostatic hypotension
- Defined as a fall of systolic blood pressure >20 mmHg upon standing after sitting or lying down (occurs within 3 minutes of standing)
- Fall of at least 30 mmHg in pts with hypertension
- Or a fall of 10mmHg diastolic blood pressure
- Symptoms: dizziness, light-headedness, fainting, possible falls
What are some causes of postural hypotension?
- Hypovolaemia, dehydration
- Autonomic dysfunction: diabetes, Parkinson’s
- Drugs: diuretics, antihypertensives, L-dopa, phenothiazines, antidepressants, sedatives
- Alcohol
If a patient gives a history suggestive of postural hypotension but it is not detected on the posture test, what other test can you perform?
- Tilt-table test
- BP and HR are measured continuously in the supine position and during passive head-up tilt
How can postural hypotension be treated?
- First-line: eliminate aggravating factors and implement lifestyle changes
- Drinking more water
- Using compression garments to enhance orthostatic tolerence
- first sit when going from supine to standing
- Learning body movements to counteract the drop in blood pressure- leg-crossing, standing on tip-toes, muscle tensing, enhance orthostatic tolerance
- Avoid straining during bowel movements or perofrming Valsalva-like maoevres
- Eat frequent small meals to lessen postprandial hypotension
- Review medications that aggravate orthostatic hypotension eg amitriptyline, diuretics, other anti-hypertensives such as alpha blockers
- Fludrocortisone (oral mineralcorticoid), used to raise blood pressure by increasing sodium levels in blood and affecting blood volume
Suggest some falls prevention strategies?
- Avoiding falls at home- eg immediately mop up spillages, remove clutter, make sure all rooms are well lit, don’t wear loose trailing clothes that can trip you up
- Take care of feet
- Strength exercises and balance exercises
- Sight tests
- Avoiding or reducing alcohol- XS can contribute to osteoporosis
How do you perform a bone health assessment?
- FRAX tool is the first step in assessing someone at risk of osteoporosis; gives you the risk of a fragility fracture over the next 10 years
- Bone mineral density is assessed using a DEXA scan- how well X-rays penetrate the bones, giving you an idea of the bone density
Why does osteoporosis occur? (pathogenesis recap)
- Imbalance of bone breakdown (osteoclasts) and bone formation (osteoblasts)
- Excessive bone resorption or decreased bone formation during remodelling
- Failure to achieve peak bone mass
- Osteoclasts increase, not matched by osteoblasts
- Reduced density of bones
How does prolonged glucocorticoid use cause osteoporosis?
- Cause increased bone resorption
- Prolonged use can result in a reduced turnover state (less bone breakdown) even though here synthesis (bone formation) is affected more leading to a loss of bone mass
List some risk factors for osteoporosis
- Post-menopause
- Female
- CKD
- Vitamin D deficiency
- Multiple myeloma
- Osteogenesis imperfecta
- Age
- Previous fragility fracture
- Corticosteroid use
- Alcohol
- Smoking
- Rheumatoid arthritis
- Low BMI
Discuss medications used for osteoporosis & the risks associated with them?
- Oral bisphosphonates- alendronate (oral), zoledronic acid (IV)
- S/E: GI disturbance, oesophagitis, headache
- C/I: pregnancy/ BF, renal impairment, hypocalcaemia, hypersensitivity
- Denosumab- monoclonal antibody, blocks osteoclast activity (subcut)
- S/E: cellulitis, hypocalcaemia (monitoring calcium required)
- Raloxifene- SERM, for post-menopausal osteoporosis
- S/E: hot flushes, vaginal dryness, leg cramps. Risk fo VTE and stroke (don’t use in ppl w/ hx of this)
- C/I: hx of VTE/ stroke, cholestasis, endometrial cancer, undiagnosed uterine bleeding, child-bearing age, lactation, breast cancer
- HRT- unopposed oestrogen or oestrogen + progesterone
- S/E: breast tenderness, leg cramps, mood changes, VTE, stroke, endometrial cancer (oestrogen only preparations), breast cancer
ADH revision recap: where is it made, why is it released?
- Synthesis: supraoptic and paraventricular nuclei in hypothalamus
- Release: from posterior pituitary, in response to high blood osmolality detected by osmoreceptors in hypothalamus
- Causes increased reabsorption of water from urine in collecting ducts of kidney
- Causes vasoconstriction and increase in arterial blood pressure
Define hyponatraemia
- Na < 135 mmol/L
How are the causes of hyponatraemia divided?
- Hypovolaemic (Na lost)
- Extra-renal loss: diarrhoea, vomiting, sweating, burns
- Urinary loss: Addison’s disease, diuretics
- Euvolemic (water gained)
- SiADH
- Hypothyroidism
- Hypervolemic (Oedematous, water excess)
- Cardiac failure, liver failure, CKD
- Hypoalbuminemia (cirrhosis, nephrotic syndrome)
How can hyponatraemia in the elderly present?
- Acute hyponatraemia: N&V, headache, coma, seizures
- Chronic: fatigue, cognitive impairment, gait deficit, falls, osteoporosis, fractures
Discuss some causes of hyponatraemia in the elderly?
- Diuretics make up one of the most common causes of hyponatraemia in the elderly
- Thiazide diuretics usually (Bendroflumethiazide, indapamide)
- Loop diuretics occasionally (furosemide)
- Other causative drugs- antipsychotics, benzodiazepines, carbamazepine (AEDs)
- SiADH causes more severe hyponatraemia
- Tea and toast hyponatraemia- may occur in those with a low GFR who follow a diet poor in salt & protein but drink a lot of water
- Low rate of osmoles excretion hence increased water reabsorption so when water consumption exceeds renal water excretion capacity, hyponatraemia occurs
What are pressure ulcers?
- Caused when an area of skin and the tissues below are damaged as a result of being placed under pressure sufficient to impair its blood supply
- Typically occurs in pts confined to bed or chair by an illness
- Referred to as pressure sores or bed sores


