Ogan Transplant Flashcards

1
Q

autograft

A

transfer of ones own tissue

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2
Q

isograft

A

identical twins

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3
Q

allograft

A

same species

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4
Q

xenograft

A

different species

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5
Q

recipient / donor criteria

A

blood type
tissue type
Size
patient acuity

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6
Q

Things that disqualify donations

A
substance abuse
infections
HTN
time without heart beat
cancer
HIV
age
irreversible organ damage
noncompliance 
unable to go thru rehan
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7
Q

what can a living donor donate

A
liver
kidney
bone marrow
pancrease
lung
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8
Q

what can a dead patient donate

A

one donor can give multiple organs

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9
Q

indications for transplant

A

-end stage organ dz
-physically capable
-psychosocial
financial means

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10
Q

KIDNEY TRANSPPLANT

A

3-4 hr
lower abdominal quadrant
-don’t need to remove native kidneys
LOS 1 week

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11
Q

Kidney survival rate

A

88-94%

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12
Q

Kidney transplant problems

A
  • thrombus/stenosis
  • URINOMA
  • Rejection
  • recurrent dz: DM glomerulonephritis, amyloids
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13
Q

LIVER TRANSPLANT
how long
LOS

A
8-12 hrs
2 weeks (2 day-1 week ICU)
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14
Q

LIVER

survival rate

A

94%

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15
Q

LIVER complications

A

hepatic non-function: if INR NOT decr. means rejection
-Infection
hepatic artery/ portal vein thrombosis
biliary tract obstruction - cholesystectomy
recurrent dz

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16
Q

HEART TRANSPLANT

  • how long
  • survival rate
A
  • 8-12 hours

- survial rate 85% but 25% die before donor is available

17
Q

HEART complications

A

rejection
CAD-within 5 yrs of transplant
HTN
-hyperlipidemia secondary to medications and then later to diet

18
Q

PANCREAS
-what can you do it with
-what does it fix
where

A
  • with kidney transplant
  • endocrine function
  • lower anterior abdomen
  • KEEP OLD PANCREASE
19
Q

what can you not do after pancreas transpant

A

NO CONTACT SPORTS

20
Q

REJECTION:

hyperacute

A

immediate: give a bolus of steroids to prevent

21
Q

REJECTION

acute

A

will reject within 3 months : depends on how fast or severe

22
Q

REJECTION:

-chronic

A

anytime after the first year

23
Q

Immunosuppression medications

A
prograf
neoral
rapamune
cell cept
steroids
24
Q

Viral infection prevention

A
handwashing
GANCYCLOVIR
ACYCLOVIR
NYSTATIN
vacccines
25
Q

psychological problems with transplant

A

chronic illness
loss of independence
medications hard to deal with
low income

26
Q

Late complications organ transplant

A

bone disease
cancer-lymphoma
recurrence of dz
** CAN TAKE 3 yr to build bone after transplant

27
Q

ethical issues

A
  • consent
  • advertising for organs
  • proliferation
  • buying organs
  • death on waiting lists
  • retransplantation