Ogan Transplant Flashcards
autograft
transfer of ones own tissue
isograft
identical twins
allograft
same species
xenograft
different species
recipient / donor criteria
blood type
tissue type
Size
patient acuity
Things that disqualify donations
substance abuse infections HTN time without heart beat cancer HIV age irreversible organ damage noncompliance unable to go thru rehan
what can a living donor donate
liver kidney bone marrow pancrease lung
what can a dead patient donate
one donor can give multiple organs
indications for transplant
-end stage organ dz
-physically capable
-psychosocial
financial means
KIDNEY TRANSPPLANT
3-4 hr
lower abdominal quadrant
-don’t need to remove native kidneys
LOS 1 week
Kidney survival rate
88-94%
Kidney transplant problems
- thrombus/stenosis
- URINOMA
- Rejection
- recurrent dz: DM glomerulonephritis, amyloids
LIVER TRANSPLANT
how long
LOS
8-12 hrs 2 weeks (2 day-1 week ICU)
LIVER
survival rate
94%
LIVER complications
hepatic non-function: if INR NOT decr. means rejection
-Infection
hepatic artery/ portal vein thrombosis
biliary tract obstruction - cholesystectomy
recurrent dz
HEART TRANSPLANT
- how long
- survival rate
- 8-12 hours
- survial rate 85% but 25% die before donor is available
HEART complications
rejection
CAD-within 5 yrs of transplant
HTN
-hyperlipidemia secondary to medications and then later to diet
PANCREAS
-what can you do it with
-what does it fix
where
- with kidney transplant
- endocrine function
- lower anterior abdomen
- KEEP OLD PANCREASE
what can you not do after pancreas transpant
NO CONTACT SPORTS
REJECTION:
hyperacute
immediate: give a bolus of steroids to prevent
REJECTION
acute
will reject within 3 months : depends on how fast or severe
REJECTION:
-chronic
anytime after the first year
Immunosuppression medications
prograf neoral rapamune cell cept steroids
Viral infection prevention
handwashing GANCYCLOVIR ACYCLOVIR NYSTATIN vacccines
psychological problems with transplant
chronic illness
loss of independence
medications hard to deal with
low income
Late complications organ transplant
bone disease
cancer-lymphoma
recurrence of dz
** CAN TAKE 3 yr to build bone after transplant
ethical issues
- consent
- advertising for organs
- proliferation
- buying organs
- death on waiting lists
- retransplantation