Office Complaints Flashcards

1
Q

Fits-Hugh Curtis

A

when purulent tubal d/c from POD ascends to RUQ causing peri hepatitis and RUQ pain

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2
Q

Reasons to Admit for Inpatient Tx PID

A
  • Severity of symptoms (ex- high fever)
  • Peritoneal signs or poss TOA (see on US)
  • If nausea and vomiting prevents oral medication use
  • Pregnant
  • If need to r/o appendicitis
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3
Q

3 Main Types Vaginitis

A
  • BV = homogenous, white d/c, + whiff (amines w/ KOH);clue cells (shaggy)
  • Candida = heterogeneous, white d/c (cottage cheese); normal pH (<4.5)
  • Trich = frothy green d/c and strawberry cervix; flagellated trich
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4
Q

Syphilis (primary, secondary, tertiary)

A
  • Primary - painLESS chancre + painLESS inguinl lymphadenopathy; appears w/in 3 wks exposure then gone in 2-6 wks
  • Secondary - systemic including maculopapular rash on hands and feet; usually 9 wks after ulcer
  • Tertiary - optic problems, tabes dorsalis (posterior columns - unsteady gait), aortic aneurysm, Argyll Robertson pupils
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5
Q

Syphilis Diagnostic Tests

A
  • screen w/ non-treponemal test (RPR or VLDR) then confirm w/ dark field microscopy
  • Initial RPR or VLDR is antibody / tiger measurement so decreases w/ treatment
  • Test of cure at 6 and 12 mo; if no dec in titers than suspect neurosphyilis
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6
Q

Syphilis Tx

A
  • If < 1 yr then 1 dose IM PCN

* If > 1 yr then 3 doses IM PCN (1 wk apart)

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7
Q

HSV

A
  • Presentation
    • Primary episode more likely systemic (fever and malaise)
    • Prodrome of numbness and tingling –> vesicle on red base
  • Dx - viral cx or PCR
  • Tx - oral acyclovir
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8
Q

Chancroid

A
  • Painful vulvar ulcer w/ ragged edges and necrotic base + painFUL lymphadenopathy
    • H ducreyi (gram neg rod) - school of fish on gram stain
    • Dx - biopsy / cx
    • Tx - oral axithromycin or IM ceftriaxone
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9
Q

How do fibroids present?

A
  • excess menstrual bleeding, compressive symptoms, uterus is irregular, midline, firm, mobile and moves w/ cervix
  • Can also have anemia secondary to menstrual blood loss
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10
Q

Fibroid Tx

A
  • 1- MEDS (NSAIDS, progesterone
  • 2- If non-responsive to meds and want to shrink before surgery then give 3 mo GnRH agonist (leuprolide); will reverse as soon as you stop drug
  • 3- Hysterectomy (indicated if still symptomatic despite medical treatment)
    • Myomectomy if desire future pregnancy
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11
Q

Concerning Fibroid Features

A

Rapid growth and hx pelvic radiation makes you suspicious of leiomyosarcoma

Do ex lap w/ hysterectomy

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12
Q

Common Breast Complaints in Young Female (2)

A

Fibrocystic Change

  • Mult irregular lumps and painful engorgement usually right before menstruation +/- serous or green d/c
  • Tx - dec caffeine, use NSAIDs, tight fitting bra or OCPs

Fibroadenoma

  • Benign smooth muscle tumor
  • Firm, rubbery, mobile, solid w/o menstrual change
  • Must do some sort of biopsy - FNA (cytology) or core needle
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13
Q

Differential for Amenorrhea

A
  • Hypothalamus - Hypothyroid or hyper-prolactin both dec GnRH pulsating release –> dec FSH / LH OR due to stress, exercise, wt loss
  • Pituitary
    • Sheehan - anterior pituitary hemorrhagic necrosis (common in labor)
    • Radiation or surgical damage to pituitary
  • Ovaries
    • Premature ovarian failure (if < 40 yo);
    • PCOS (will shed when given progesterone challenge)
  • R/o pregnancy
  • Outflow Problems
    • Cervical stenosis - leads to retrograde menstruation which can present as cramps abdominal pain 5-7 days / mo
    • Asherman - adhesions after a uterine curettage - endometrium does not respond to hormones
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14
Q

Diagnosis and Treatment of Asherman

A

No response to progesterone therapy; no withdrawal bleeding

  • Diagnose by hysterosalpingogram, saline infusion sonogram of uterine cavity or hysteroscopy
  • Tx - operative hysteroscope and lysis of adhesions; may leave pediatric foley or IUD in place to prevent recurrence of adhesions
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15
Q

What is the #1 cause of unilateral serosanguinous nipple d/c?

A

Intraductal papilloma

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16
Q

Indication for BRCA testing

A

2 first degree relatives w/ breast cancer

17
Q

Mgt of Breast Cyst

A

1- US

2- FNA

If straw colored then can just observe

If any other color then send for cytology

18
Q

Differential for Galactorrhea

A
  • Secondary to hypothyroidism
    • Pathogenesis: hypothyroid –> inc TRH –> inc prolactin
    • Inc prolactin –> inhibits GnRH pulsatile release –> amenorrhea
    • Give thyroxine
  • Pregnancy - test
  • Pituitary prolactinoma - headaches or visual disturbances (bitemporal hemi)
    • MRI
  • Breast stimulation
  • Meds - psychotropics (anything that dec dopamine will inc prolactin because less inhibition)
  • Chest Wall Trauma
19
Q

Tx of Prolactinoma

A
  • Can treat w/ bromocriptine (used in pregnancy) or cabergoline (both dopamine agonists) or surgical resection
  • Complications of surgery - transient DI, pan-hypopituitarism, CSF leakage, meningitis, hemorrhage
  • Can also dec size w/ bromocriptine first ythen resect
20
Q

Differential for Hirsuitism (5)

A

1- Cushing - hyperglycemia, HTN, buffalo hump/central obesity; treatment is surgical removal

2- Adrenal Tumor - RAPID hirsuitism and virilization w/ ab mass; see elevated DHEA

3- CAH - ambiguous genitalia + hypotension; inc 17-hydroxyprogesterone
* Must replace mineralocorticoid and cortisol

4- PCOS - insidious onset of hirsuitism rarely w/ virilization

5- Sertoli-Leydig tumor - RAPID onset hirsuitism and virilization w/ adenexal mass; inc testosterone

21
Q

Differential for Hirsuitism (5)

A

1- Cushing - hyperglycemia, HTN, buffalo hump/central obesity; treatment is surgical removal

2- Adrenal Tumor - RAPID hirsuitism and virilization w/ ab mass; see elevated DHEA

3- CAH - ambiguous genitalia + hypotension; inc 17-hydroxyprogesterone
* Must replace mineralocorticoid and cortisol

4- PCOS - insidious onset of hirsuitism rarely w/ virilization

5- Sertoli-Leydig tumor - RAPID onset hirsuitism and virilization w/ adenexal mass; inc testosterone

22
Q

Thought Process for Primary Amenorrhea

A
  • Is there breast development?
  • NO
    • Hypergonadotropic Hypogonadism
      • Most common is Turner (45, X); no estrogen because streak ovaries; high FSH
    • Hypogonadotropic Hypogonadism (CNS problem)
      • Causes - stress, exercise, pituitary adenoma, poor nutrition, chronic illness, Cushing, Kallman (lack of GnRH producing cells)
  • YES
    • Mullerian Dysgenesis
      • Still have breast development (estrogen) and pubic/axillary hair development (androgens)
      • 46, XX
      • No uterus or Fallopian tubes, absent or short vagina + 1/3 have renal abnormalities too
    • Androgen Insensitivity
      • 46, XY but feminization; no internal or external male genitalia because not responsive to androgens; no female genitalia either because anti-mullerian in embryogenesis
      • Have breast development because estrogen still present from peripheral conversion; no pubic hair because that requires androgens
    • Phenotypically female
    • Remove gonads after puberty
23
Q

Normal Female Puberty

A
  • Thelarche (avg 10.8) - breast development
  • Adenarche (avg 11) adrenals - axillary and pubic hair
  • Menarche (12.9) - mentstruation
24
Q

Definition of Delayed Puberty

A

No secondary characteristics by age 14

25
Q

Precocious Puberty (definition, causes, tx)

A
  • Breast development b/f 7 (6 in blacks)
  • Central (GnRH pulsation - have FSH and LH)
    • Hydrocephalus, brain tumor, head trauma
  • Peripheral - FSH and LH barely detectable
    • Granulosa cell tumor (juvenile subtype) or adrenal tumor
  • Can also be idiopathic
  • Presenation - inc height earlier than peers but then overall shorter because epiphyseal plates close earlier
  • Tx - GnRH agonist if idiopathic
26
Q

5 Factors of Infertility + How to Eval Ea

A
  • Ovulation
    • Basal body temp recording - measure in bed under tongue each day and look for .5 degree spike
    • Ask about menses regularity
    • Can also do luteal phase biopsy and see secretory endometrium to confirm
    • Tx - clomiphene citrate
  • 2- Uterus - hysterosalpingogram; if not patent then do hysteroscope
  • 3- Tubes - if suspected on hysterosalpingogram then do lap
  • 4- Male Factor - Semen analysis
  • 5- Peritoneal Factor (endometriosis) - do lap
    • Esp if other signs - dysmenorrhea or dyspareunia
27
Q

Semen Analysis

A

Volume (> 2mL), count (>20 million sperm / mL), 50% motile, 30% morphologically normal

Should be abstinent 2-3 days before test

If abnormal result repeat in 2-3 months

28
Q

Lichen Sclerosis

A
  • Peak in pre-pubertal and post-menopausal women
  • Presentation
    • Vulvar itching (worse at night) + constricted introitus which may cause pain w/ sex
    • Figure 8 around vulva and around anus
    • Paper thin skin +/- excoriations
  • Do vulvar biopsy - will show thinned epidermis, hyperkeratosis, elongated rete pegs; will also r/o cancer
    • If cancer - surgical staging, removal + ipsilateral inguinal nodes
  • Diff - includes psoriasis (silver scale) and recurrent vulvar candidiasis (esp if DM)
  • Tx - prevent itching, recommend hygiene, corticosteroid cream (clobetasol)
29
Q

Bartholin Gland Abscess

A
  • At 5 and 7 o clock; become enlarged and painful w/ inflammation
  • Often polymicrobial
  • Tx - Word catheter or marsupilization not just simple incision and drainage otherwise will recur