Off Spec Flashcards

1
Q

GLUT 1

A

Insulin adds glucose channel proteins to cell membrane of liver cell
Increases permeability
High affinity for glucose
Prevelant in blood brain barrier
To rapidly take up glucose since the brain uses 20%
Used in essential functions like nervous conduction

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2
Q

CRISPR

A

Clustered
Regularly
Interspaced
Short
Palindromic
Repeats
Found in ecoli
Genes coding for cas proteins as part of an immune response against bacteriophage
Crisper cas 9 repair system locates target site on DNA sequence of a cystic fibrosis patient with guide RNA
Cas nucleated can cut the DNA at the faulty site and allow the repair template containing normal DNA sequence to integrate in its place
So fells can then produce the function CFTR protein

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