ODONTOGENIC TUMORS - Epithelial Flashcards
Most common epithelial odontogenic tumor
Most aggressive
Most clinically significant
Ameloblastoma
Clinical features of Ameloblastoma
Unilateral jaw expansion
Mandible (molar-ramus area)
Vital teeth
Biological subtypes of Ameloblastoma (PCSMA)
- Peripheral / extraosseous
- Cystic / Unicystic
- 📌Solid/Multicyctic - most common
- Malignant ameloblastoma
- Ameloblastic carcinoma
Radiographic Appearance Ameloblastoma
- Radiolucent w/ well defined sceloritc border
- Soap bubble / Honeycomb appearance
Microscopic / Histopath
📌Palisading columnar cells (Ameloblasts in enamel organ)
📌 Aspirate= straw colored fluid (cholesterol crystals)
SOAP BUBBLE / HONEYCOMB Appearance CAMA
- Cherubism
- Ameloblastoma
- Myxoma
- Aneurysmal bone cyst
Histologic Patterns: of Ameloblastoma (FPGBDA) 🦠💉
📌Follicular/Simple - most common 📌Plexiform 📌Granular 📌Basaloid / Basal Cell 📌Desmoplastic 📌 Acanthomatous pattern
BE**
📌mimics normal dental follicle
📌islands of cells stellate reticulum like pallisading columnar cells
Follicular/Simple Histologic pattern of Ameloblastoma
interconnecting strands or cords
Plexiform
granular cells
Granular cells
basal cell carcinoma
Basaloid/ Basal Cell
Fibrous tissues thin strands/ scatter stroma
Desmoplastic
islands, squamous metaplasia, keratinization/ keratin pearls
Acanthomatous Pattern
BCC aka
Farmer’s Carcinoma
Clinical features of CEOT / Pindborg Tumor
📌Mandible (molar ramus area)
📌Unilateral jaw expansion
Radiographic Appearance of CEOT / Pindborg Tumor
📌RDL / Lucent opaque
📌Driven snow appearance
☑️ Large polyhedral/polygonal cells
☑️Calcified amyloid substsnce arranged in concentric patterns (‼️LIESEGANG RINGS‼️)
CEOT / Pindborg Tumor
INDICATIONS of BIOPSY‼️
📌Doesn’t heal more than 2 wks
📌Persistent lesion for more than 2 wks unresponsive tx
📌 Persistent hyperkeratotic
📌Lesions- high risk areas: floor of mouth, posterolateral border of the tongue
📌 Suspect malignancy
📌Bony lesions clinically radippographically
<1cm , 2in1 tx, elliptical/ football shaped
📌 2-3mm normal tissue
📌better coaptation
📌deposit 1 cm away
Excisional Biopsy
> 1 cm suspect maligancy
may damage near vital stuctures
periphery border
narrow & deep
Incisional biopsy
Gauge 18 best
Gauge 16
Aspirational Biopsy
Ameloblastic & Cystic lesion
Straw- colored
OKC
creamy colored creamy white cheese like
infected pus
Yellow Green foul odor
Sinus , traumatic bone cyst
Air
BV, Aneurysmal bone cyst
Blood
Storage volume of BIOPSY
10% Buffered Formalin
surface of tongue
Exfoliative Cytology
Clincal Features of Adenomatoid Odontogenic Tumor (Adenoameloblastoma)
📌Maxilla (anterior region)
📌Impacted maxillary Canine
Radiographic Appearance of Adenomatoid Odontogenic Tumor /AdenoAmeloblastoma
RDL/ mixed lucent opaque
Rosettes & ductlike structures
‼️BE‼️
Microscopic/ Histopath of Adenoameloblastoma /
‼️BOARD Q.
Px swelling maxilla upon histopath tumors resemble the gland
Gland like structure histological composed of duct like structures
Adenomatoid Odontogenic tumor (Adenoameloblastoma)