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odontogenic neoplasms Flashcards

1
Q

Ameloblastoma benign or malignant?

A

benign, but aggressive

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2
Q

Ameloblastoma orgin

A

odontogenic epithelial origin

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3
Q

Ameloblastoma Microscopically, cells resemble

A

the ameloblasts of the enamel organ, but no enamel is produced

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4
Q

whats the most common ondontogenic neoplasm

A

ameloblastoma

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5
Q

Ameloblastoma seen when

A

wide age range 30-70’s

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6
Q

Ameloblastoma makes up ___% of oral pathology biopsy

A

.2%

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7
Q

Ameloblastoma where

A

Most (80-85%) occur in the mandible, usually the molar-ramus region

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8
Q

Ameloblastoma 20% associated with what

A

impacted tooth

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9
Q

Ameloblastoma growth

A

grows slowly, destroying tissue, but usually expanding rather than perforating bone

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10
Q

Ameloblastoma clinical

A

Typically asymptomatic except for swelling

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11
Q

Ameloblastoma radiographic

A

A small lesion usually presents as a unilocular radiolucency with well-defined borders
As the lesion progresses, the classic multilocular expansile radiolucency frequently develops

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12
Q

Ameloblastoma (desmoplastic variant)

A

Distinctive radiologically as well as histologically
Radiographs usually show a poorly demarcated radiolucency with numerous radiopaque flecks
Similar in appearance to benign fibro-osseous lesion

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13
Q

Ameloblastoma patterns

A

follicular and plexiform

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14
Q

Ameloblastoma histo

A

Small tumor islands which show cuboidal or columnar cells at their periphery
The center of the tumor islands is composed of loosely arranged polyhedral epithelial cells that resemble stellate reticulum

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15
Q

Ameloblastoma trt

A

en bloc resection

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16
Q

Ameloblastoma prognosis

A

guarded

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17
Q

Ameloblastoma recurrence rates

A

With simple curettage, recurrence rates reported to be 50-90%
Even with marginal resection, recurrence rates up to 15%

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18
Q

Ameloblastoma, maxilla or mandible require more aggressive trt

A

maxilla

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19
Q

Peripheral Ameloblastoma

A

asymptomatic gingival mass in a middle-aged adult, usually mandible

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20
Q

Peripheral Ameloblastoma size

A

Typically less than 2 cm in diameter

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21
Q

Peripheral Ameloblastoma trt and reoccurrence

A

Important to note that this is an innocuous lesion that can easily be cured by local excision, little tendency to recur

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22
Q

Calcifying Epithelial Odontogenic Tumor

A

Rare odontogenic epithelial neoplasm initially described by Pindborg in 1956

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23
Q

CEOT (Pindborg Tumor) histo, derived from what

A

stratum intermedium

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24
Q

CEOT (Pindborg Tumor) who and when

A

Mean age at diagnosis - 40 years, with no sex predilection

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25
CEOT (Pindborg Tumor) where
Most arise in the posterior mandible
26
CEOT (Pindborg Tumor) clinically
Asymptomatic; swelling may be noted | 50% associated with an impacted tooth
27
CEOT (Pindborg Tumor) radiographically
Diffuse or well-circumscribed radiolucency unilocular when small With growth, lesion may become multilocular Radiopaque flecks often develop as lesion enlarges
28
CEOT (Pindborg Tumor) histo
Sheets or strands of polyhedral epithelial cells with eosinophilic cytoplasm The nuclei are frequently pleomorphic, but mitoses are rare
29
CEOT (Pindborg Tumor) major histo characteristics
amyloid material that calcifies, forming lamented structures called Liesegang rings
30
CEOT (Pindborg Tumor) trt
Conservative excision with peripheral ostectomy
31
CEOT (Pindborg Tumor) recurrence rate
15% recurrence rate
32
Adenomatoid Odontogenic Tumor who and when
Usually arises in a younger patient, mean age - 18 years, with 75% under 20 years of age females
33
Adenomatoid Odontogenic Tumor where
maxillary more | 75% in anterior
34
Adenomatoid Odontogenic Tumor 75% associated with _____ teeth
impacted
35
Adenomatoid Odontogenic Tumor clinical
asymptomatic | sometimes swelling
36
Adenomatoid Odontogenic Tumor radiographically
Well-circumscribed unilocular radiolucency that may contain radiopaque flecks Separation of roots or displacement of adjacent teeth occurs frequently
37
radiographic features that distinguish Adenomatoid Odontogenic Tumor from dentigerous cyst
When associated with an impacted tooth, the lesion often extends apically beyond the cemento-enamel junction
38
Adenomatoid Odontogenic Tumor histo
Well-encapsulated lesion | The tumor cells form swirling spindle-cell nests with duct-like structures of varying sizes
39
Adenomatoid Odontogenic Tumor histo feature that sometimes need to be seen
Foci of basophilic calcified material may also be seen
40
Adenomatoid Odontogenic Tumor trt
enucleation
41
Adenomatoid Odontogenic Tumor prognosis and recurrence
excellent | rare
42
Ameloblastic Fibroma who and when
younger patients in first two decades of life
43
Ameloblastic Fibroma where
posterior mandible (70 percent)
44
Ameloblastic Fibroma clinically
small lesions are asymptomatic, larger ones produce painless swelling
45
Ameloblastic Fibroma radiographic
smaller lesions are unlocular, bigger lesions can become multilocular with well defined boarders
46
Ameloblastic Fibroma histo
Myxoid connective tissue that resembles dental papilla that contains strands and islands of odontogenic epithelium that resembles dental lamina
47
Ameloblastic Fibroma, CT resembles what
dental papilla
48
Ameloblastic Fibroma epithelial islands can resemble what?
ameloblastoma
49
Ameloblastic Fibroma odontogenic epithelial resembles what
dental lamina
50
Ameloblastic Fibroma trt
aggressive curettage
51
Ameloblastic Fibroma prognosis
good
52
Ameloblastic Fibroma recurrence rate
low
53
Ameloblastic Fibro-Odontoma
Odontogenic tumor with features of ameloblastic fibroma as well as odontoma
54
Ameloblastic Fibro-Odontoma who and when
children, 10 years old average age
55
Ameloblastic Fibro-Odontoma where
Equal frequency in mandible and maxilla
56
Ameloblastic Fibro-Odontoma clinically
Asymptomatic swelling with large lesions Failure of tooth eruption may be noted
57
Ameloblastic Fibro-Odontoma radiographically
Well-circumscribed unilocular, or occasionally multilocular, radiolucency Varying amounts of calcified material having the density of tooth structures
58
Ameloblastic Fibro-Odontoma, often associated with what
impacted tooth
59
Ameloblastic Fibro-Odontoma histo
Odontoma areas (usually complex odontoma) together with areas of ameloblastic fibroma. characteristics of both
60
Ameloblastic Fibro-Odontoma trt
conservative curettage
61
Ameloblastic Fibro-Odontoma prognosis
excellent
62
Odontoma
probably not a true neoplasm but a odontogenic hamartoma.
63
Odontoma, two forms
compound and complex
64
Odontoma when
Most are detected during the first two decades of life, mean age of 14 years
65
Odontoma where
Slightly more frequent in the maxilla compared to the mandible
66
Odontoma associated with what
unerupted tooth
67
compound odontomas seen mainly where
anterior maxilla
68
complex odontomas seen mainly where
posterior portion or maxilla or mandible
69
compound odontoma clinically
as a collection of small malformed teeth surrounded by a narrow radiolucent rim, often overlying an impacted tooth 
70
compound odontoma histopath
shows the formation of multiple small malformed teeth
71
complex odontoma histopath
shows a mixture of dentin, enamel matrix, cementum, odontogenic epithelium and dental papilla
72
odontoma trt and prognosis
enucleation | excellent
73
Odontogenic Myxoma
Benign neoplasm assumed to be of odontogenic origin because the jaw bones are the only skeletal sites affected
74
Odontogenic Myxoma when
Primarily affects young adults, but seen over a wide age range Average is 25-30 years
75
Odontogenic Myxoma where
Mandible affected slightly more than maxilla
76
Odontogenic Myxoma, larger lesion present with what
asymptomatic expansion of bone
77
Odontogenic Myxoma radiographically
Unilocular when small; multilocular when large | May have a "soap-bubble" appearance
78
Odontogenic Myxoma histo
Spindle-shaped or stellate-shaped fibroblastic cells set in a myxoid background The lesional proliferation tends to infiltrate the adjacent bony trabeculae
79
Odontogenic Myxoma trt and prognosis
small lesions- curettage large lesions en bloc segmental resection prognosis- good
80
Odontogenic Myxoma recurrence rates
up to 25%
81
Cementoblastoma when
under 25 years old usually
82
Cementoblastoma where
mandibular molar region
83
Cementoblastoma growth
slow growing, may produce expansion or pain
84
Cementoblastoma radiographically
Well-circumscribed radiopaque mass with a fine radiolucent border Fused to the resorbed root of a tooth, usually a mandibular first molar
85
Cementoblastoma usually fused to what
resorbed root of a tooth
86
cementoblastoma look like if excised
Trabeculae of mineralized material that resembles cementum | The trabeculae are rimmed by plump, angular cells that represent neoplastic cementoblasts
87
Cementoblastoma differential diagnosis
osteoblastoma, osteosarcoma
88
Cementoblastoma trt
Surgical extraction of the involved tooth with enucleation of the lesion Alternatively, the tooth can be endodontically treated followed by root amputation and removal of the lesion with the involved root
89
Cementoblastoma prognosis
excellent

Oral Path 3 (3 decks)

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