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Oral Histology Exam 1 > Odontogenesis > Flashcards

Odontogenesis Flashcards

1
Q

what is odontogenesis?

A

formation of tooth tissues from stem cells originating in the ectoderm primary germ layer

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2
Q

when does odontogenesis begin?

A

6th embryonic week

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3
Q

what two basic tissues that arise from the ectoderm primary germ layer are involved in tooth development?

A

epithelium and mesenchyme

they contain stem cells that become the cells that form tooth tissues

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4
Q

what are the epithelial stages?

A

epithelial dental lamina stage
epithelial bud stage
epithelial cap stage
epithelial bell stage (enamel organ)

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5
Q

what is the epithelial stages classified based on?

A

histologic shapes of the epithelial tissue within a mesenchymal tissue environment

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6
Q

what are tooth germ stage based on?

A

odontogenic epithelial and mesenchymal tissue combines/ cells of each tissue induced specifically to become formative cells of dentin, enamel, cementum and pulp tissues

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7
Q

what are the three parts of tooth germ?

A

enemel organ (bell): epithelium
dental papilla: mesenchyme
dental follicle: mesenchyme

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8
Q

primary dental lamina stage

A

two epithelial invaginations appear in lower anterior region of the lower jaw and later in the same week in the upper jaw
invaginations descend into the underlying mesenchymal tissue (ectomesenchyme) and continue posteriorly within the mesenchyme as continuous epithelial bands

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9
Q

what is the facial band called?

A

vestibular lamina

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10
Q

what is the lingual band called?

A

primary dental lamina

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11
Q

fate of vestibular lamina

A

cell death will occur in the center of the vestibular lamina leaving a space known as the “vestibule”

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12
Q

fate of primary dental lamina

A

cells arising from the dental laminae (primary and secondary) become the odontogenic epithelial part of a tooth germ

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13
Q

what is an epithelial bud?

epithelial bud stage

A

cells at the deep end of the dental lamina, where a tooth is destined to form, will develop into epithelial knobs- epithelial bud
surrounded by mesenchymal tissue

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14
Q

timeline of primary buds

A

6 to 8 weeks in utero- upper arch a little behind

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15
Q

timeline of permanent buds

A

4 months in utero to 5 years postnatal

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16
Q

how many epithelial buds arise from the primary dental lamina of each arch?

A

16, 10 primary teeth and 6 permanent molars

each succedaneous tooth has its own secondary dental lamina that arises from lingual side of primary dental lamina

17
Q

cap stage

A

odontogenic epithelial in shape of a cap. site of enamel knot concentration of epithelial cells of cap is a signaling center- determines if tooth will develop to become anterior or posterior tooth

18
Q

epithelial bell stage

A

epithelial cap undergoes growth and develops into a bell shaped epithelial structure called enamel organ.
epithelium arranged into 4 distnct cell layers

19
Q

4 epithelial cell layers of enamel organ

A
  1. inner epithelial layer
  2. stratum intermedium epithelial layer
  3. stellate reticulum epithelial layer
  4. outer epithelial layer
20
Q

secondary dental lamina

A

lingual to primary tooth germ

arises from primary dental lamina not oral epithelium

21
Q

tooth germ

A

combined epithelial enamel organ and closely associated ectomesenchymal tissue that is continuous from around the epitheum to within the epithelium

22
Q

destiny of enamel organ

A

avascular
inner epithelial cells differentiate into ameloblasts- specialized epithelial cells
after formaton of enamel is complete, the ameloblasts and other layers of enamel organ come toether over the surface of the enamel as protecrive structure called reduced enamel epithelium

23
Q

destiny of dental papilla

A

vascular
undifferentiated cells (stem cells) become odontoblast, fibroblast, reserve cells
ultimately become the pulp tissue of tooth

24
Q

destiny of dental follicle

A

vascular
its stem cells become cementoblast, fibroblast, osteoblast and reserve cells
ultimately becomes periodontal ligament of periodontium

25
Q

cervical loop

A

rim of the epithelial bell (enamel organ)

site where inner and outer cell layers merge

26
Q

what forms at the cervical loop?

A

double epithelial layer called hertwig’s epithelial root sheath

27
Q

what are the functions of root sheath?

A

determines root dentin outline

determines number of root canals of tooth

28
Q

when does central incisors primary buds occur

A

6 weeks in utero

29
Q

when does second molars primary buds occur

A

8 weeks in utero

30
Q

when does first molar permanent buds occur

A

4 months in utero

31
Q

when does central incisor permanent buds occur

A

5 months in utero

32
Q

when does second molar permanent buds occur

A

10 months postnatally

33
Q

when does third molar permanent buds occur

A

5 years postnatally

Oral Histology Exam 1 (5 decks)

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