Ocular side effects of systemic medication

Question 1

Name some antidepressants

Answer 1

Citalopram
Fluoxetine
Amitriptyline
Sertraline
Diazepam

Question 2

Ocular side effects of antidepressants?

Answer 2

Dry eye
Intermittent blurring
Photophobia
Blepharospasm

Question 3

Ocular side effects of contraceptive pill?

Answer 3

Dry eye

Decreased tolerance to contact lens wear

Retinal vascular abnormalities (haemorrhage, thrombosis etc)

Question 4

Name some HTN medications

Answer 4

Ramipril
Losartan
Amlodopine
Atenolol

Question 5

Ocular side effects of HTN meds?

Answer 5

Dry eye, miotic pupils

Question 6

Ocular side effects of blood thinner (anit-coagulants-warfarin)?

Answer 6

Subjconjunctival haemorrhage

Retinal haemorrhage

Question 7

Name some statins (antihyperlipidemic for high chol)

Answer 7

Simvastatin

Atorvastatin,

Question 8

Ocular side effects of statins?

Answer 8

Dry eyes

Question 9

Name some medications for cardiac arrhythmia

Answer 9

Amiodarone

Digoxin

Question 10

Ocular side effects of amiodarone?

Answer 10

Vortex keratopathy

Corneal epithelial depos

Optic neuropathy

Question 11

Ocular side effects digoxin?

Answer 11

Photopsia

Red-green colour deficiency

Question 12

Name some anti-malarials and what else are they used for?

Answer 12

Chloroquine
Hydroxychloroquine

Malaria and rheumatoid arthritis

Question 13

Ocular side effects Chloroquine &

Hydroxychloroquine?

Answer 13

Bull’s eye maculopathy

Corneal deposits

Colour vision defects

Question 14

What tests should optometrist carry out to best detect abnormality on patient taking Hydroxychloroquine?

Answer 14

Amsler chart (red)

Central fields
HFA 10-2

Or test with red stimuli

Colour vision testing

Fundus photography

Question 15

Name some corticosteroids used for allergic, rheumatic and inflammatory disease etc

Answer 15

Prednisolone

Dexamethosone

Question 16

Ocular side effects of steroids

Answer 16

Posterior subcapsular cataract

Severe reduction in visual acuity is rare but patients may complain of glare and photophobia

Raised IOP

Potentiation of viral, bacterial and fungal ocular infections (keratitis)

Scleral thinning

Papillodema

Question 17

Name a breast cancer medication

Answer 17

Tamoxifen

Question 18

Ocular side effects of tamoxifen?

Answer 18

Corneal change- whorl keratopathy

Macula oedema, pigmentary change and haemorrhage

If VA becomes reduced- its irreversible

Question 19

Name a medication taken for prostate enlargement

Answer 19

Flomax

Question 20

Ocular side effects of flomax?

Answer 20

floppy iris syndrome

Question 21

Name a medication for under-active or removed thyroid

Answer 21

Levothyroxine

Question 22

Ocular side effects of Levothyroxine?

Answer 22

Diplopia
Ptosis
EOM paralysis
Hyperaemia

Question 23

Name a medication for Tuberculosis

Answer 23

Ethambutol

Question 24

Ocular side effects Ethambutol

Answer 24

Optic neuritis

Question 25

Name a medication for MS and hepatitis

Answer 25

Interferons

Question 26

Ocular side effects of Interferons

Answer 26

Optic neuritis, conjunctivits, cotton wool spots, dry eyes

Question 27

Name some anti allergy medications

Answer 27

antihistamine: cetirizine,
olopatadine

Mast ceel stabilisers: sodium cromoglicate,
lodoxamide

Question 28

Ocular side effects of anti allergy medications?

Answer 28

Dry eye, reduced accomodation/blurring, mydriasis

Question 29

Name an epilepsy medication

Answer 29

Topamax

Question 30

Ocular side effects of topamax?

Answer 30

ACG

Question 31

Name an acne medication

Answer 31

Minocycline

Question 32

Ocular side effects of Minocycline?

Answer 32

Raised ICP and papilloedema