Ocular Pharmacology Flashcards
1
Q
What alpha-2 agonist drug is used in the treatment of glaucoma and what is its MOA and potential side effects?
A
- Brimonodine and Apraclonidine.
- decreases synthesis of aqueous humor
- Mydiasis (NEVER used in closed angle), blurry vision, allergic reactions, optic pruritis.
2
Q
What beta blocker can be used in the treatment of glaucoma and what is its MOA and potential side effects?
A
- Timolol
- Decreases aqueous humor production.
- No pupillary or vision changes
3
Q
What prostaglandin F receptor agonists can be used in the treatment of glaucoma and what is its MOA and potential side effects?
A
- Lantanoprost, Bimatoprost
- Increase outflow of aqueous humor
- darkens the color of the iris
4
Q
What carbonic anhydrase inhibitor can be used in the treatment of glaucoma?
A
- Acetazolamide, Dorzolamide
5
Q
What cholinomimetics can be used in the treatment of glaucoma and what is the MOA and potential side effects?
A
- Direct-> pilocarpine; increase outflow via contraction of ciliary muscle and opening of trabecular meshwork. Use in emergencies.
- Indirect-> physostigmine; opens trabecular meshwork.
6
Q
What is the receptor present of the radial/dilator muscle of the eye and what drug is used to as an agonist for glaucoma treatment?
A
- Alpha-2.
- Bromonidine and Apraclonidine.
