Ocular Lubricants

Question 1

82% of dry eye pts wished there was

Answer 1

There was something more than ATs to treat their dry eyes

Question 2

Common visual complaints in dry eye

Answer 2

Fluctuating vision w blinking
Glare
Blurred vision
Eye fatigue

Question 3

Dry eye, caused by unstable tear film can result in

Answer 3

Reduced vision, inflammation and discomfort

Question 4

Factors that can disrupt homeostatic control and destabilize the tear film

Answer 4

Rosacea
MGD
Accurate (can kill MG)
CLs

Question 5

Certain conditions can cause an inflammation driven dry eye

Answer 5

Sjorgrens
RA, Lupus
Fibromyalgia

Question 6

Inflammation effect on MG

Answer 6

In the resolution phase, fibroblasts come in and re- keratinize the glands stopping the oil from coming out

Question 7

Conj and cornea wont be as healthy in dry eye because

Answer 7

Inflammation causes apoptosis

Question 8

CL intolerance is a big clue for

Answer 8

Dry eye

Can be resolved by using peroxide based systems to get rid of build up

Question 9

It’s common for dry eye pt’s to also complain of

Answer 9

Dry skin

Paying attention might be essential for the early detection and relief of ocular or skin dryness

Question 10

Brimonidine

Answer 10

Used as a cream to help rosacea

Question 11

Although dry eye is a heterogenous disorder of the ocular surface, the common denominator is

Answer 11

Inflammation

Question 12

Difference between time when pt with irritated eye symptoms are worse

Answer 12

End of the day - dry eye

Morning- bleph

Question 13

Almost exclusive for bleph, free fatty acids and soaps released after bacterial lipases break down the MG secretions

Answer 13

Burning eyes

Question 14

What kind of pain seen in dry eye

Answer 14

Neuropathic pain, dry eye is constantly irritating the tear film and cornea causing damaged nerves

Dry eye symptomsare due to over reacting nerves

Question 15

Dry eye questionnaires are helpful because

Answer 15

They can document improvement that they usually don’t notice

Question 16

First line of defense of the tear film

Answer 16

Lipid layer

Protects the tear film, against desiccation and protects corneal noniceptors

Question 17

Why is blinking important?

Answer 17

It’s how the glans releases it’s oil

Question 18

A function of a healthy tear film is a tropic environment

Answer 18

Growth factors for corneal epithelium

Question 19

Tears when you have a dry eye change by

Answer 19

Increase in osmolarity which is what causes the irritation

Question 20

Age related dry eye

Answer 20

The most common form

Question 21

Immunologic change in dry eye

Answer 21

Once T cells are activated, inflammatory cytokines are released causing more inflammation

Question 22

Testosterone treatment for dry eye can

Answer 22

Bind to corticosteroid and can have some anti inflammatory effect

Question 23

What happens if you dont treat MGD

Answer 23

Lipid changes
Eyelid inflammation
Bacterial overpopulation
Lipase release toxins

Question 24

All dry eye has increased

Answer 24

Osmolarity and inflammation

Question 25

MGD pathophysiology

Answer 25

Increased evaporation | Increased osmolarity

Question 26

Visual issues in dry eyes are caused by

Answer 26

Tear film instability - glare | Corneal SPK - blurred vision

Question 27

ATs lack

Answer 27

Complex mixture of growth factors

Question 28

Dry eye pts blink

Answer 28

More bc there no stable tear film

Question 29

Gels are better because of

Answer 29

Increased viscosity increases retention time

Question 30

Natural lubricant

Answer 30

HA is added to ATs

Question 31

Try to avoid a certain persevative in ATs

Answer 31

BAK, it builds up

Question 32

Cell changes in dry eye

Answer 32

Junction between cells start to break down, increase in corneal turnover

Question 33

Theratears and saline help with dry eye because

Answer 33

Used to rinse eye, and helps with inflammation because cytokines are being diluted

Question 34

ATS dont contain specific anti inflammaoptry, lysozyme, lactoferrin, immunoglobulin a, lipid binding proteins and growth factors. MGP pts should use

Answer 34

Lipid supplemented tears

Question 35

Blink has

Answer 35

HA

Question 36

Rash is a sign of

Answer 36

Inflammation

Question 37

Discontinuing steroids will cause

Answer 37

Inflammation to come back

Question 38

Filamentary keratitis

Answer 38

Is caused when you have you dont have enough tears to dissolve mucous

Question 39

Filamentary keratitis is a condition with

Answer 39

strands composed of degenerated epithelial cells and mucus develop on and adhere to the corneal surface causing pain and FBS

Question 40

Vigamox is a

Answer 40

Non preserve topical antibiotic

Question 41

Démodé treatement

Answer 41

Only tea treat oils can kill it | It’s messy, smelly and it stings

Question 42

MGD obstruction

Answer 42

Cant fix itself

Question 43

Glands become more

Answer 43

Asymmetric when they start to get plugged