Ocular Lubricants Flashcards

1
Q

82% of dry eye pts wished there was

A

There was something more than ATs to treat their dry eyes

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2
Q

Common visual complaints in dry eye

A

Fluctuating vision w blinking
Glare
Blurred vision
Eye fatigue

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3
Q

Dry eye, caused by unstable tear film can result in

A

Reduced vision, inflammation and discomfort

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4
Q

Factors that can disrupt homeostatic control and destabilize the tear film

A

Rosacea
MGD
Accurate (can kill MG)
CLs

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5
Q

Certain conditions can cause an inflammation driven dry eye

A

Sjorgrens
RA, Lupus
Fibromyalgia

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6
Q

Inflammation effect on MG

A

In the resolution phase, fibroblasts come in and re- keratinize the glands stopping the oil from coming out

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7
Q

Conj and cornea wont be as healthy in dry eye because

A

Inflammation causes apoptosis

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8
Q

CL intolerance is a big clue for

A

Dry eye

Can be resolved by using peroxide based systems to get rid of build up

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9
Q

It’s common for dry eye pt’s to also complain of

A

Dry skin

Paying attention might be essential for the early detection and relief of ocular or skin dryness

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10
Q

Brimonidine

A

Used as a cream to help rosacea

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11
Q

Although dry eye is a heterogenous disorder of the ocular surface, the common denominator is

A

Inflammation

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12
Q

Difference between time when pt with irritated eye symptoms are worse

A

End of the day - dry eye

Morning- bleph

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13
Q

Almost exclusive for bleph, free fatty acids and soaps released after bacterial lipases break down the MG secretions

A

Burning eyes

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14
Q

What kind of pain seen in dry eye

A

Neuropathic pain, dry eye is constantly irritating the tear film and cornea causing damaged nerves

Dry eye symptomsare due to over reacting nerves

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15
Q

Dry eye questionnaires are helpful because

A

They can document improvement that they usually don’t notice

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16
Q

First line of defense of the tear film

A

Lipid layer

Protects the tear film, against desiccation and protects corneal noniceptors

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17
Q

Why is blinking important?

A

It’s how the glans releases it’s oil

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18
Q

A function of a healthy tear film is a tropic environment

A

Growth factors for corneal epithelium

19
Q

Tears when you have a dry eye change by

A

Increase in osmolarity which is what causes the irritation

20
Q

Age related dry eye

A

The most common form

21
Q

Immunologic change in dry eye

A

Once T cells are activated, inflammatory cytokines are released causing more inflammation

22
Q

Testosterone treatment for dry eye can

A

Bind to corticosteroid and can have some anti inflammatory effect

23
Q

What happens if you dont treat MGD

A

Lipid changes
Eyelid inflammation
Bacterial overpopulation
Lipase release toxins

24
Q

All dry eye has increased

A

Osmolarity and inflammation

25
Q

MGD pathophysiology

A

Increased evaporation

Increased osmolarity

26
Q

Visual issues in dry eyes are caused by

A

Tear film instability - glare

Corneal SPK - blurred vision

27
Q

ATs lack

A

Complex mixture of growth factors

28
Q

Dry eye pts blink

A

More bc there no stable tear film

29
Q

Gels are better because of

A

Increased viscosity increases retention time

30
Q

Natural lubricant

A

HA is added to ATs

31
Q

Try to avoid a certain persevative in ATs

A

BAK, it builds up

32
Q

Cell changes in dry eye

A

Junction between cells start to break down, increase in corneal turnover

33
Q

Theratears and saline help with dry eye because

A

Used to rinse eye, and helps with inflammation because cytokines are being diluted

34
Q

ATS dont contain specific anti inflammaoptry, lysozyme, lactoferrin, immunoglobulin a, lipid binding proteins and growth factors.
MGP pts should use

A

Lipid supplemented tears

35
Q

Blink has

A

HA

36
Q

Rash is a sign of

A

Inflammation

37
Q

Discontinuing steroids will cause

A

Inflammation to come back

38
Q

Filamentary keratitis

A

Is caused when you have you dont have enough tears to dissolve mucous

39
Q

Filamentary keratitis is a condition with

A

strands composed of degenerated epithelial cells and mucus develop on and adhere to the corneal surface causing pain and FBS

40
Q

Vigamox is a

A

Non preserve topical antibiotic

41
Q

Démodé treatement

A

Only tea treat oils can kill it

It’s messy, smelly and it stings

42
Q

MGD obstruction

A

Cant fix itself

43
Q

Glands become more

A

Asymmetric when they start to get plugged