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Ocular Biology 2 > Ocular Circulation > Flashcards

Ocular Circulation Flashcards

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1
Q

What’s the principle function of the choroid?

A

To nourish the outer 1/3 of the retina

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2
Q

What are the other functions of the Choroid?

A

Absorb excess light from RPE, contribute to Bruch’s membrane, provide protective canal for vessels and nerves (suprachroidal space), stabilizes ocular temperature

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3
Q

What are the 3 layers of vessels in the choroid?

A

Choriocapillaris (inner), Sattler’s Layer (middle), Haller’s Layer (outer)

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4
Q

What size are the vessels of the choriocapillaris? What type of vessels are they?

A
  • small (40-60microns)

- fenestrated

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5
Q

What size are the vessel of Sattler’s Layer? What type of vessels are they?

A
  • medium vessels

- nonfenestrated Vessels

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6
Q

What size are the vessels of Haller’s layer? Where can we find this layer?

A
  • large vessels

- Part of choroidal stroma

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7
Q

What can we find in Haller’s Layer?

A

The 4 vortex veins

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8
Q

What are the main functions choriocapillaris?

A

Supplies nutrients and blood, removes waste from outer retina and macular region.. has a relationship with RPE and Bruch’s membrane

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9
Q

How many layers are found in the choriocapillaris region?

A

Single layer of broad capillaries

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10
Q

The choriocapillaris is internal to ______ layer and external to _____ _____.

A

Sattler’s Layer, bruch’s membrane

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11
Q

Which layer contains the largest capilalries of the eye and allows passae of multiple RBCs without damage?

A

Choriocapillaris

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12
Q

What are the 3 sources of chroidal blood supply?

A

Short cililary arteries, long ciliary arteries and anterior ciliary arteries

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13
Q

The posterior pole develops the _____

A

ora serrata

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14
Q

What is the gradient of development for the layers of the choroid?

A

Choriocapillaris develops first&raquo_space; Sattlers Layer&raquo_space; Hallers Layer

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15
Q

RPE induces _____ in the choroid.

A

angiogenesis

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16
Q

Development of choroidal vasculature depends on what?

A

The presence of differentiated RPE and production of inductive signals

17
Q

Neural Ectoderm develops into?

A

Basement membrane of RPE which secretes bruch’s membrane

18
Q

Mesodermal Mesenchyme develops what?

A

Endothelium of BV and Blood elements of the choroid

19
Q

Neural Crest develops what?

A

Melanocytes, Fibrocytes and smooth muscle of blood vessles

20
Q

Hard drusen are found what kind of RPE?

A

Thinned but Intact RPE

21
Q

What are the generalizations of Soft Drusen?

A
  • localized RPE detachments
  • More likely to have vision loss
  • High risk for Wet ARMD
22
Q

Angioid Streaks represent breaks where? What are the other generalizations?

A

In bruch’s membrane

There will be radiating lines from optic disc (looks like a cracked sidewalk)

Possible choroidal neovascularization

23
Q

The choroid supplies the _____ of the retina, and the CRA supplies the _____ of the retina

A 
Choroid = outer 1/3
Retina = Inner 2/3
24
Q

The Central Retinal System has and inner capillary plexus that is found in what layer? What is another name for this plexus?

A

Ganglion Cell Layer

Superficial Capillary Plexus

25
Q

The Central Retinal System has and outer capillary plexus that is found in what layer? What is another name for this plexus?

A

Inner Nuclear Layer

Deep Capillary Plexus

26
Q

What is the outer location of the blood retinal barrier?

A

Tight junctions near the apical side of the RPE

“outer” closer to the choroid

27
Q

What is the inner location of the blood retinal barrier?

A

Nonleaky Tight junctions joining endothelial cells of retinal blood vessels

“inner” closer to the vitreous

28
Q

Which ocular tissue has the greatest blood flow (even more than the brain and kidneys)?

A

Choroid

29
Q

True or False: Retina has autoregulation and Choroid does not?

A

True.

The choroid does not have the ability to maintain blood flow with increased ocular pressure or lack of nutrients

30
Q

Intraocular pressue will mostly effect blood flow from which ocular tissue the most?

A

Greatest effect - Choroid

The higher the pressure, moderate increments in pressure reduce blood flow

31
Q

Automatic Innervation is found in which ocular tissues?

A

Choroid, CB and Iris

NOT RETINA

32
Q

Autoregulation is found in which ocular tissues?

A

CB, Iris and Retina

33
Q

What is the rate of flow in the choroid and retina, respectively?

A 
Choroid = 667
Retina = 31

Ocular Biology 2 (5 decks)

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