Ocular anatomy Flashcards

1
Q

what is orbit?
what is its roles?

A

bony socket containing the eye

formed from a number of fused bones
serves:
-protect the delicate eye
-provide a mounting point for the six striatal muscles that control the ocular movement.

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2
Q

what are the structures in the internal eye?
their functions?

A

Sclera
Tough, outer protective coat

Lens
transparent biconvex structure, suspended by lens zonules

Cilliary body
provides attachment for lens zonules. Changes the focusing power of the lens

Iris
regulates light entering eye attached by cilliary body

Choroid
maintains the eye’s blood supply

Retina
inner layer containing visual photoreceptors (rods & cones)

Optic nerve
transmits images from photoreceptors to the brain

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3
Q

tear production by lachrymal glands
what are the different types of tears

A

Basic tears (to maintain a tear film on the corneal surface for optical, metabolic and lubricant purposes)

Reflex tears are induced in response to chemical or mechanical irritation, cold, light, etc)

Emotional

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4
Q

lipid layer
what does it consist of
where is it found
what is its role

A

It consists mainly of sterol esters, triacylglycerols and phospholipids, free sterols and free fatty acids

It spreads over the aqueous layer during eye opening

The lipids play an important role in reducing the evaporation rate to maintain the normal tear osmolality

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5
Q

what consists in the aqueous layers in the cornea?

A

Inorganic salts
Glucose
Urea
Retinol
Ascorbic acid
Various proteins
Lipocalins (tear-specific pre-albumins)
Immunoglobulins
Lysozyme
Lactoferrin
Glycoproteins

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6
Q

what is the function of tear films?

A

Prevention of corneal drying
Transport of oxygen and nutrients to the cornea
Maintenance of cornea clean and smooth
Protection against infection

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7
Q

what is the pH of tear films?

A

7.3-7.7
pH lowest on awakening

pH can also vary between 5.2 and 9.3 depending on age and diseases;

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8
Q

why is tears more acidic in contact lens wearer

A

The tears are more acid in contact-lens wearers due to impediment of the efflux of carbon dioxide, and more alkaline in the case of diseases such as dry eye, severe ocular rosacea and lacrimal stenosis.

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9
Q

what is the buffer capacity of tears determined by?

A

Buffer capacity of the tears is determined by bicarbonate ions, proteins and mucins;

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10
Q

what is nasolacrimal drainage?
how does it work?

A

Under normal conditions the human tear volume is about 7-9 L and it is relatively constant

The maximum amount of fluid that can be held in the lower eyelid sack is 25-30 L, but only 3 L of a solution can be incorporated in the precorneal film without causing it to destabilise;

When eye-drops are administered, the tear volume is suddenly increased which can cause rapid reflex blinking

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11
Q

what is blinking and its role?

A

Blinking is an important defence mechanism of the eye. The brisk blinking reflex is usually fast enough to precede high-speed foreign bodies approaching the eye;

Blinking is also essential for the periodic reforming of the tear film;

Blinking also activates a pumping mechanism for the drainage of tears through the lacrimal drainage apparatus;

The blink rate in humans is 15-20 per min (roughly one blink every 5-7 s. In rabbits it is slower than in humans (roughly 5 per min).

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12
Q

epithelium = lipophilic
stroma - hydrophilic

why is it like this?

A

protect eye ball
to temper foreign substances getting in to the eyeball

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13
Q

what is the functions of the cornea?

A

passage of lights

reflection of light

protection

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14
Q

what is aqueous humour
what is it composed of?

A

The aqueous humour is a transparent viscous fluid located in the anterior chamber of the eye

Composition
98% water
amino acids
electrolytes
ascorbic acid
glutathione
immunoglobulins

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15
Q

what is the function of aqueous humour?

A

It maintains the intraocular pressure and inflates the globe of the eye

It provides nutrition for the avascular ocular tissues (posterior cornea, trabecular meshwork, lens, and anterior vitreous);

May serve to transport ascorbate in the anterior segment to act as an antioxidant agent;

Potential immune response to defend against pathogens (immunoglobulins);

Light refraction

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16
Q

what is the lens and its functions?

A

Along with the cornea, it helps to refract light to be focused on the retina;

The lens is elastic and can change shape, getting thicker to focus close objects and thinner for distant objects;
The lens consists of the lens capsule, the lens epithelium, and the lens fibers

17
Q

what is vitreous humour?
what is its function.

A

The vitreous humour is the clear gel that fills the space between the lens and the retina

Functions:
helps to maintain normal anatomic expansion of the globe
impedes the diffusion of substances between the retina and the anterior segment of the eye.
small water-soluble substances in the retina may diffuse into the vitreous across the blood-retina barrier.
acts as a reservoir of substances such as oxygen, glucose and ascorbic acid, which support the metabolism of adjacent structures
acts as a reservoir for metabolic waste products

18
Q

what is the composition of vitreous humour?

A

water (99%);
a network of collagen fibrils;
large molecules of hyaluronic acid;
peripheral cells (hyalocytes);
inorganic salts;
glucose;
ascorbic acid

19
Q

where are photoreceptors located?
when does rods act?
when does cones act?

A

Photoreceptors located on retinal surface

Rods act in low light levels, do not provide colour and have little spatial resolution

Cones operate at higher light levels, perceive colour and allow good spatial resolution

20
Q

what is Precorneal tear film

A

“Three layers theory”:

The precorneal tear film consists of a superficial lipid layer, a central aqueous layer and an inner mucus layer.

21
Q

what is the The optic nerve
where is it located
function

A

Rod/cone (photoreceptors) activation causes action potential generation in the optic nerve.

Optic nerve is a bundle of ~1.25108 nerves

Pass into skull interior via optic canal to meet at optic chiasma.

Nerves project to visual cortex in occipital lobes