OcPhysioT2_corn_aqueous Flashcards
How is the angle determined under the Maurice Lattice Theory?
Ratio of the spacing of the scattering elements to the wavelength of the light.
What is needed for a zero order to occur?
The spacing is less than 1/2 the wavelength
Does an exact measurement of spacing is required for transparency?
Nope.
Where is the majority of keratocytes located?
In the anterior part of the cornea.
What are the functions of keratocytes?
IIMRW Intracorneal comm Interlamellar tethering Matrix turnover Reservoir for glycogen Wound healing by new matrix
What are the functions of proteoglycans?
Provide tissue volume
Maintain spatial order of collagen fibrils
Resist compressive forces
Give viscoelstic properties to the tissue
Regulating collagen fibril assembly.
Core proteins of proteoglycan attach to….
GAGs extend into….
Collagen fibrils
Interfibrillar space
Are GAGs positively or negatively charged?
Negatively
What kind of structure does GAGs form with each other?
Dumbbell-like structure.
Is there more dermatan in the front or back part of stroma?
Front
Does dermatan like oxygen rich or oxygen poor environments?
Oxy rich
Explain to me Dermatan’s take on water?
MOre efficient at holding water.
Absorbs less water than Keratin.
Does scattering occur a whole lot in the cornea?
No,
Because cornea is thin.
What happens if scattering is increased in the cornea?
Loss of transparency
How does light scatter mas in the cornea?
Imbalance b/w fibrils, keratocytes, or extrafibrillar matrix
Does the Limbal blood vessels supply the cornea with a lot of oxygen?
Nope.
Very minimal.
Who supplies the endothelium with oxygen?
The aqueous.
WHere does the stroma receive its supply of oxygen?
From the aqueous and tears.
Why is oxygen able to diffuse towards the cornea from the aqueous and the tear layer?
Because oxygen tension in the cornea is lower than both tears and aqueous.
Why can’t the epithelium receive oxygen from the aqueous?
There are hoggers out there.
The endothelium and keratocytes of the stroma consume the oxygen first.
How does the endothelium maintain corneal thickness?
By pumping bicarbonate into the anterior chamber.