OCD Flashcards

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1
Q

Define OCD

A
  • OCD: recurrent obsessional thoughts or compulsive acts, or commonly both
  • Obsessions: Unwanted intrusive thoughts, images or urges that repeatedly enter the individuals mind. Distressing for the individual who attempts to resist them + recognises them as absurd + product of own mind
  • Compulsions: repetitive, stereotyped behaviours or mental acts that a person feels driven into performing. They are overt (observable by others) or covert (mental acts that are not observable)
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2
Q

RFs OCD

A
  • Developmental factors → neglect, bullying, abuse, social isolation
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3
Q

Biological pathophysiology of OCD

A

• Neurochemical: ↓ serotonin
• Abnormalities in frontal cortex + basal ganglia
o Childhood infection w/ group A beta haemolytic streptococci → autoimmune reaction → damage to basal ganglia
• Genetic contribution

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4
Q

Behavioural/ psychological causes of OCD

A
  • Compulsive behaviour is learned + maintained by operant conditioning → the anxiety created by the obsession is reduced by performing the compulsion (therefore the need to perform the compulsion is ^)
  • Obsessions are conditioned stimuli (stimulated by an anxiety provoking event)
  • Compulsions = learned + reinforced (anxiety-reducing avoidance)
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5
Q

CFs and most common compulsion and obsession

A
  • SYMPTOMS OF ANXIETY
  • Most common compulsion: checking > washing/cleaning
  • Most common obsession: being contaminated

OCD cycle: 1: Obsessions create 2: ANXIETY → builds up until 3: compulsion carried out → 4: RELIEF

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6
Q

DDx OCD

A
  1. Obsessions + compulsions: Eating disorders, anankastic personality disorder, body dysmorphic disorder
  2. Primarily obsessions: anxiety disorders (phobic…), depressive disorder, Hypochondriacal disorder, schizophrenia
  3. Primarily compulsions: tourette’s, kleptomania
  4. Organic: dementia, epilepsy, head injury
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7
Q

Rx OCD

A
  1. Psychological
    a. CBT (including ERP: exposure and response prevention)
    b. Behavioural therapy

c. Psychotherapy
2. Pharmacological
a. 1st line: SSRIs (sertraline, citalopram, fluoxetine)
b. 2nd line: Clomipramine (combined w/ citalopram in more severe cases
c. Adjuncts: anti-psychotic (haloperidol)

Also:
• Physical: ECT (if suicidal)
• Identity suicide risk
• Rx co-morbid depression

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8
Q

Define somatoform disorder

A
  • Group of disorders whose Sx’s suggest or take the form of a physical disorder but in the absence of a physiological illness, leading to the presumption they are caused by psychological factors
  • Sufferers repeatedly seek medical attention
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9
Q

RFs somatoform disorder

A

Risk factors CRAMPS

  • Childhood abuse
  • Reinforcement of illness behaviours
  • Anxiety disorders
  • Mood disorders
  • Personality disorders
  • Social stressors
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10
Q

Pathophysiology and aetiology somatoform disorder

A

Biological
• Neuroendocrine genes (genetics)

Psychological
• A high proportion of those w/ PTSD have somatoform disorder
• Association between somatization + physical or sexual abuse

Social
• Adopting of ‘sick role’ to gain relief from stress
o Pt’s adopt a sick role which provides relief from stressful or unachievable interpersonal expectations (primary gain). This offers attention, care from others and, in some societies, financial gain (secondary gain)

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11
Q

CFs somatoform disorder

A

ICD-10 Classifications:

PUSHy SOMATOFORM (pt’s push for Ix’s to be performed)

  1. Persistent somatoform pain disorder**
  2. Undifferentiated somatoform disorder
  3. Somatization disorder**
  4. Hypochondriacal disorder (including body dysmorphic disorder)**
  5. SOMATOFORM autonomic dysfunction
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12
Q

What is somatization disorder

A
  • Briquet’s syndrome
  • Multiple, recurrent and frequently changing physical Sx’s not explained by a physical illness
  • W>M (10:1)
  • Long Hx of contact w/ medical services
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13
Q

Common symptoms somatization disorder

A

o GI → Abdo pain, N+V, bloating, regurgitation, loose bowel motions, swallowing difficulty
o CV → Chest pain, SOB at rest, palpitations
o CU → Dysuria, frequency, incontinence, vaginal discharge, menstrual problems
o Others → discoloration or itching of skin, arthralgia, paraesthesia in limbs, headaches, visual disturbance

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14
Q

ICD 10 somatization disorder diagnosis

A

• ICD10 (requires all 4):

  1. 2+ years of physical Sx’s unexplained by detectable physical disorder
  2. preoccupation w/ Sx’s causes physical distress which leads to repeatedly seeking medical consultations + requesting Ix’s
  3. continuous refusal by pt’s to accept reassurance from Dr’s that there is no physical cause to their sx’s
  4. 6+ symptoms
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15
Q

Hypochondriacal disorder

A
  • Pt misinterprets normal bodily sensations, which leads them to the non-delusional preoccupation that they have a serious physical disease
  • Refuse to accept reassurance from Dr’s
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16
Q

Persistent somatoform pain disorder

A
  • Persistent (6+ mths) and severe pain that can’t be explained by a physical disorder
  • Pain occurs usually as result of psychosocial stressor + emotional difficulties
  • Difference w/ somatization disorder → Pain = primary feature (no or small number of other Sx’s)
17
Q

Ix Somatoform disorders

A

• Thorough physical exam
• Blood tests: FBC (anaemia, infection), U+Es (electrolyte disturbance), LFTs (liver or biliary pathology), CRP (infection, inflammation), TFTs (thyroid dysfunction)
• Further Ix’s:
o GI Sx’s: AXR, Stool culture, OGD, colonoscopy, diagnostic laparoscopy
o CV Sx’s: ECG, 24hr tape, ECHO, angiogram
o GU: urine dipstick, MSU, cystoscopy

18
Q

Rx Somatoform disorders

A

Biological

  • Antidepressants (SSRIs) for underlying mood disorder
  • Physical exercise (enhances self-esteem + can esp. help body dysmorphia)

Psychological
- CBT = MAINSTAY

Social

  • Stress relieving activities (meditation + long walks + exercise)
  • Interview/involve family members who serve to reinforce sick role
19
Q

Think somatoform disorder if…

A

Think somatoform disorder if: multiple Sx’s from dif systems, vague Sx’s, chronic course, presence of a mental health disorder, Hx of extensive diagnostic testing, rejection of previous clinicians

20
Q

Dissociative (conversion) disorder define

A
  • Persistent or recurrent episodes of distressing feeling of unreality or detachment
  • Either to outside world (derealisation) or to the person’s own body, thoughts, feelings or behaviour (depersonalisation)
21
Q

Aetiology dissociative (conversion) disorder

A
  1. Dissociation → ‘separating off’ certain memories from normal consciousness (psychological defence mechanism – used to cope w/ emotional conflict that is so distressing for the pt that it is prevented from entering the conscious mind)
  2. Conversion → distressing events are transformed into physical Sx’s (like somatoform disorders can lead to primary/secondary gain)
22
Q

CFs dissociative (conversion) disorder

A
  • Pt may report they are a ‘passive observer’ of what is going on around them or of their own actions
  • Emotional numbness (inability to experience feelings)
  • Dream/trance-like state
  • Alterations in perception
  • Insight preserved (unlike passivity phenomena) – pt recognises the experience as abnormal

IMPORTANT → painful/stressful thoughts are subconsciously converted into more bearable physical Sx’s by the pt

23
Q

Categories of dissociative disorder (ICD-10 Subclassifications)

A
  1. Dissociative amnesia: loss of memory (amnesia) usually centred on traumatic events (+ usually partial and selective)
  2. Dissociative fugue: all features of dissociative amnesia + purposeful travel beyond everyday range (amnesia for this travel)
  3. Dissociative stupor: absence of voluntary movement + normal responsiveness to external stimuli
  4. Trance and possession disorders: temp. loss of the sense of personal identity + full awareness of the surroundings
  5. Dissociative motor disorders: loss of ability to move the whole or a part of a limb(s)
  6. Dissociative convulsions: convulsions (mimic epileptic seizures) → tongue biting, incontinence to urine = rare → consciousness maintained (or replaced by stupor/trance)
  7. Dissociative anaesthesia + sensory loss: numbness, tingling (paraesthesia)
24
Q

Ix dissociative disorder

A

• Use rating scale: CAMBRIDGE DEPERSONALIZATION SCALE
• Exclude organic causes (hyperventilation, hypoglycaemia, migraine, epilepsy…): CT/MRI, EEG…

25
Q

Rx dissociative disorder

A

Poor evidence for successful Rx:
o Psychological → CBT
o Biological → citalopram (if marked anxiety add clonazepam)