OCD Flashcards
What developmental process goes wrong to cause OCD?
endochondral ossification
Why is surgical removal of OCD lesions an important consideration in horses?
It can cause damage to the joint
What is endochondral ossification?
The process in epiphysis where the cartilage template has vascular in-growth leading to bone formation (subchondral bone)
What is the pathophysiology of why endochondral ossification fails in OCD cases?
Failure of vascular invasion leads to failure of ossification
What may exacerbate an osteochondrosis lesion?
Chondrocyte death, damage to extracellular matrix or trauma
Osteochondrosis latens definition
Focal cartilage necrosis which heals and is not clinically relevant
Osteochondrosis manifesta definition
Cartilage does not ossify to bone in a focal area
-aka theres cartilage where bone should be
-results in a weak spot (stress riser) which can result in fracture through the cartilage
If a stress riser results in a fracture through both cartilage and bone, what is this called?
Osteochondral fragment
-usually occurs due to shear forces
Osteochondrosis dissecans definition
Trauma causes shearing off of either cartilage or cartilage and bone
How does a subchondral bone cyst form?
Trauma on a weight bearing surface causes a crack in the cartilage allowing joint synovial fluid to flow in. Increased pressure in the bone then leads to inflammation and bone resorption
-enough trauma in a normal joint without OCD can still result in a cyst
When do you lose hope for an early OCD lesion healing?
Once a foal is over 18 months of age
Which is more difficult to treat- OCD or bone cysts?
Bone cysts - can end up with joint inflammation, arthritis, tears in meniscus, pain in the bone itself
What causes horses to be predisposed to OCD lesions?
High growth rate, high plane of nutrition, heritability, trauma (excess trauma on healthy cartilage, normal trauma on defective cartilage), overexercise
How does cartilage get nutrition?
From the movement of the joint/weight bearing (moves synovial fluid into the cartilage)
What about the diet can predispose to OCD?
Too much phosphorus or excess calcium + energy
Which trochlear ridge is thinner?
Lateral ridge
What are some radiographic signs of OCD lesions
Lucency, sclerosis, fragmentation, soft tissue swelling
What are the hallmark signs of OCD?
Joint effusion, lameness (worsens with flexion due to swelling of joint capsule)
T/F: A foal with a very swollen hock can be diagnosed with X-rays without blocking
True-not true for older horse (always block these)
T/F: Arthritis in joint decreases prognosis in OCD cases
True
How can you figure out if a cartilage flap exists because it cannot be seen on X-ray?
Ultrasonography, contrast radiography, CT, MRI, nuclear scintigraphy, PET scan
T/F- Arthroscopy is a diagnostic technique for OCD
True! Can diagnose and treat all at once
Why are subchondral bone cysts harder to diagnose?
Often wont see effusion unless fetlock is affected (as the bone is affected more than the joint)
-lameness can be delayed until stressed
-may not block or only partially block
-often have arthritis before these are diagnosed
T/F: Lateral femoral condyle has a more round surface
F- medial
What does the treatment and prognosis of OCD depend on?
The joint involved -if more accessible more likelihood of success
-age of horse- if younger much higher likelihood of success
How do you decide whether to bring a horse to surgery for OCD?
severity of signs, occupation of horse, potential for OA, age
Why do you preserve cartilage when possible?
As it increases the likelihood of post-op success due to preservation of hyaline cartilage (vs fibrocartilage)
-debrided ocd beds heal with fibrocartilage which does not have the same mechanical properties as hyaline (not as resilient)
What medical therapy options are available to treat OCD?
-reducing trauma vs exercise restriction, relieve synovitis through adequan, legend, hysvic, or steroids (use caution)
What are the goals of arthroscopy for ocd patients?
-fully explore the joint and assess for damage, joint lavage, remove loose and free osteochondral fragments, debride loose and diseased cartilage, do no harm to normal attached cartilage
What post-op protocol is usually used after arthroscopic surgery?
60 days minimum stall rest with a gradual return to exercise