occupational risks (bloodborne pathogens) Flashcards
these organisms such as bacteria, viruses, and even parasites that are carried in blood and cause diseases in people.
pathogenic
examples of primary concerns bloodborne pathogens
HIV, HCV, HBV
it is a dna virus that belongs to the hepadnaviridae family
HBV
what are the modes of transmission for HBV
parenteral, sexual, or perinatal
it is a mode of transmission where HBV is transmitted by intimate contact with HBV contaminated blood or other body fluids such as seminal fluid, vaginal secretions, and saliva
Parenteral
mode of transmission where their is a possibility that this bloodborne pathogen to be passed on or transmitter to the baby from the mother, most likely during delivery.
perinatal
incubation for HBV
45-90 days
HBV has a high chance of progression to
chronic state
chronic development of hepatitis will increase the risk of ___________ and also ________
liver cirrhosis and cancer of the liver or hepatocellular carcinoma
complications of hepatitis b virus, how many percent of cases may develop chronic hepatitis with increased risk of liver cirrhosis and cancer of the liver or hepatocellular carcinoma
10%-90%
HBV can survive at least ____ week in dried blood on environmental surfaces or contaminated needles and instruments
1 week
signs and symptoms of HBV
fever, fatigue, loss of appetite, nausea, dark urine, vomiting, abdominal pains, joint pains, and jaundice
the main risk for health workers being exposed to HBV is being?
being stuck with a HBV contaminated needle or other sharp objects
Measures to prevent HBV infections:
- screening blood donors
- treating plasma-derived products to inactivate HBV
- implementing infection control measures
- immunization of hepatitis b vaccine
examples of implementing infection control measures
no recapping of needles, wearing proper ppe, and prioritizing one’s welfare
an enveloped, single stranded RNA virus belonging to the Flaviviridae family
hepatitis c virus
modes of transmission for HCV
parenteral, sexual, and perinatal
HCV has a high chance of progression to _____
chronic state
HCV patient will really progress to chronic infections because HCV attacks the ____and may lead to inflammation.
HCV attacks the liver
what percent of develop chronic infection with increased risk of liver cirrhosis, hepatocellular carcinoma, and autoimmune manifestations in HCV.
85%
symptoms of HCV include
Jaundice, fatigue, abdominal pain, loss of appetite,, intermittent nausea, dark urine, and joint pains.
some HCV situations don’t show any symptoms at all and don’t know they are infected until decades later when liver damage shows up in ____ tests.
routine tests
the etiologic agent of the acquired immunodeficiency syndrome
human immunodeficiency virus
what are the former names of human immunodeficiency virus the 4 types
HIV 1 (discovered 1983-1984)
Human T-cell lymphotropic virus-type III (HTLV III)
Lymphadenopathy-associated virus (LAV)
AIDS-associated retrovirus (ASR)
HIV that causes AIDS attacks the __________ leaving the body at higher risk of developing more serious conditions.
human immune system cells
Signs and Symptoms of HIV
Flu like symptoms. (Fever, chills, appearance of rash, night sweats, muscle sore, sore throat, fatigue, swollen lymph nodes, or the presence of mouth ulcers.)
the signs and symptoms usually appear _ -_ weeks after infection while other people who are already infected with the virus may not feel sick.
2-4 weeks
HIV does not survive long and cannot reproduce outside a human host; so once transmitted, in order for the virus to replicate inside the body it will use the ____?
immune system
a related but genetically distinct virus from HIV -1 which discovered in 1986
HIV 2
Majority of infection of HIV 1 occurred in
West Africa
how is the transmission of HIV 2?
it has the same transmission process as HIV 1 and may also cause AIDS
what is the difference between HIV 1 and HIV 2?
HIV 2 is less pathogenic and has a lower rate of transmission
What are the 3 major routes of transmission of HIV?
- intimate sexual contact
- contact with blood or any other body fluids (parenteral route)
- Perinatal route (infected mother to infant)
transmission of virus may happen through vaginal or anal intercourse (which the major of the cases of HIV infection.)
intimate sexual contact
most cases worldwide of HIV can attributed to ____ contact
heterosexual contact
in the USA, the largest number of cases has resulted from anal intercourse in _______ males.
homosexual males
in order to prevent the transmission of parenteral route, prevention may include__________ and _________________ for HIV
screening of the blood and organ donors for HIV
what are the body fluids that are not considered to be infectious unless they contain visible blood.
saliva, sputum, nasal secretions, tears, sweat, urine, vomit, and feces.
transmission is through pregnancy, by transfer of blood during delivery or through breast feeding.
perinatal route
steps to reduce transmission of HIV through perinatal:
(HAT)
- HIV screening
- Administration of antiretroviral drug for HIV+ pregnant women
- The use of infant formula by infected mothers
Disease caused by bloodborne pathogens:
- syphilis
- malaria
- zika
- babesiosis
- brucellosis
- Creutzfeldt-Jakob disease
- human t-lymphotropic virus type 1
- ebola virus disease
an infection caused by treponema pallidum (spirochete)
syphilis
mode of transmission for syphilis
sexual contact (primary mode of dissemination) and perinatal route
syphilis sore is usually in what area of the body?
genital area
the causative agent of syphilis characteristic has:
coils and periplasmic flagella
syphilis has how many stages
4 stages
once contact has been made with a susceptible skin site, there will be thickening of ____
endothelial cells
thickening of endothelial cells that usually occurs with
aggregation of lymphocytes, plasma cells, and macrophages
sore appears on the spot where
the bacteria entered the body
chancre or the sore usually develops within ___ days after infection, within 21 days being the averaged
10-90 days
in men, chancre usually occurs
outside the penis
in women chancre usually occurs ___ and may go undetected
in the vagina or on the cervix
the primary stag usually lasts from ____ weeks during in which the lession may heal
1-6 weeks
it is a stage in syphilis infection where systematic dissemination or the spread of organism usually happens
secondary stage
symptoms for secondary stage of syphilis:
generalized lymphadenopathy, malaise fever, pharyngitis, and rashes on skin or mucous membrane
these rashes of syphilis may not be itchy and may also be accompanied by ___
wart-like sores in the mouth and in genital area
in secondary level, patient may exhibit neurological signs such as
visual disturbances, hearing loss, tinnitus, and facial weakness
in secondary level syphilis, lesions persist from a few days to ___ weeks
few days to 8 weeks
spontaneous healing may occur, as the __ stage
primary stage
the third stage of the syphilis infection level is the
latent stage
without treatment, syphilis will ____ in the body even if there are no signs and symptoms
remain in the body
it follows the disappearance of the secondary stage
the latent stage
in this stage of syphilis, it is characterized by a lack of clinical symptoms.
latent stage
the patient of syphilis this time are non-infectious, except for pregnant women
latent stage
what are the 2 types of latent stage syphilis
early latent syphilis
late latent syphilis