Obstetrics Flashcards
Number of times a woman has been pregnant?
Gravidity
Number times a woman has given birth?
Parity
When should preconception care begin?
3 months prior to conception
Folic acid recommendation is
400 mcg
What trimester does the blood pressure decrease
1st and 2 nd trimester
What trimester does the blood pressure return to baseline
3rd trimester
Chronic HTN increases the risk for what complications during pregnancy?
- Pre-eclampsia
- Preterm labor
- Placental abruption
Complications of diabetes during pregnancy?
- Congenital malformations
- Pregnancy loss
- Fetal macrosomia/growth restriction
- DKA
- Maternal and perinatal mortality
What percentage of women with asthma during pregnancy will.
- Get worse
- No change
- Improve
1/3
Why are ace inhibitors not given during pregnancy?
- They can cause renal agenesis
If a woman stops smoking prior to 24 weeks in pregnancy what is the outcome?
- The same as someone who has never smoked
complications from smoking during pregnancy include?
- Placental abruption
- Preterm labor
- Premature rupture of membranes
- fetal growth restriction
- SIDS
During pregnancy systemic vascular resistance is increased or decreased?
Decreased
What happens to mean arterial pressure during pregnancy?
decreases
Does the heart rate increase or decrease during pregnancy?
increases
Is cardiac output increased or decreased during pregnancy
increased
During pregnancy blood volume increases to
40-45% above the non pregnant state
What makes pregnant women at increased risk for blood clots during pregnancy
Their blood is hyper-coagulable
Is pregnancy an immunodeficient state
yes
During pregnancy how many centimeters does the diaphragm rise?
4 cm
During pregnancy does residual lung volume increase or decrease?
Decrease
Does tidal volume increase or decrease in the pregnant female
Increases
does functional residual capacity decrease or increase during pregnancy
decrease
Cardiac output increases during pregnancy does the heart rate increase as well?
the heart rate increases during pregnancy
During pregnancy where is the woman’s heart located?
The heart is displaced leftward and upward
What is the reason for acid reflux for women in the first and third trimester
Decreased tone of the lower esophageal sphincter
What happens to the size of the kidney’s during pregnancy?
The are slightly larger due to increased blood volume.
When is hydro-nephrosis more common during pregnancy and which ureter is most often times affected?
Common after 2nd trimester and the right is more often affected than the left
During pregnancy:
- Serum creatinine is?
- Creatinine clearance is
- GFR is?
- Serum Cr-decreased
- Cr Clearance-increased
- GFR-increased
What is the likely cause of glucose in the pregnant woman’s urine besides GD
- Glucose because of the increased GFR
basal metabolic rate in pregnancy increases by
10-20%
In pregnancy water retention is increased by 6.5 l due to what?
Decrease plasma osmolality
During pregnancy does progesterone and estrogen increase or decrease?
Increase
During pregnancy does aldosterone and renin increase or decrease?
Increase
During pregnancy does relaxin increase or decrease
increase
The uterus increased to how many grams by the time the fetus is term?
5 liters
Linea nigra is a result of what during pregnancy
Increase in melanocytes
What is Naegele’s rule?
LMP subtract 3 months and add 7 days.
Beta HCG is at least what number should something be seen in the uterus on vaginal u/x
2000
If the beta hcg is at least (1) clinicians should be able to see something in the uterus using an abdominal u/s
6000
Serum pregnancy test is
quantitative
Gestational age on ultrasound in the 1 st trimester should be how many weeks from the LMP
1 week
Which trimester u/s is most accurate for establishing gestational age?
2nd trimester
Initial prenatal visit routine screening?
- Blood type RH factor
- CBC
- Infections: Rubella, HIV, RPR/VDRL, Hep B
- Pap smear and culture gonorrhea and chlamydia
- Hemoglobinopathies and inherited disease
When is the fetal anatomy u/s conducted?
Between 18-22 weeks gestation
If a patient has a random 140 result is that a positive screen for GD?
yes
When is the pertussis vaccine given?
3rd trimester
GBS screening is done during what weeks of pregnancy?
35-37 weeks
How is hyperemesis gravidarum treated?
- Slow IV hydration
- Correct electrolyte disturbance
- anti-emetic vitamin b6 and doxylamine
What reverses the side effects of extrapyramidal movements related to Reglan
- Benadryl
Which of the following can be a complication of IV hydration in patients with hyperemesis gravidarum?
Worsening thiamine deficiency
What 3 ways are women screened for down syndrome?
- Free fetal DNA
- Integrated sequential contingency screening 11 weeks to 13 weeks and 6 days. Done as probability
- Quad screen 15 weeks and 22 weeks 6 days gestation
If screening test are abnormal for down syndrome what are the two invasive test that are done?
- Chorionic villi sampling
2. amniocentesis
What is considered reactive on a non stress test of the fetus?
Reactive = two accelerations of greater than 15 bpm lasting at least 15 seconds over a 20 minute time period.
What is included in the biophysical profile
- Fetal movement
- Fetal tone
- Fetal breathing
- Ammonitic fluid
- Non stress test
Biophysical profile can be used as confirmation the fetus is doing well in place of?
- A non reactive stress test
A Biophysical score of >8 means
- Fetus is doing well
A score of 6 is equivocal on a biophysical profile but also means
if the fetus is term delivery is warranted
A score of <4 on a biophysical profile is concerning for what?
asphyxia
A contraction stress test is negative if
Less than 50% of contractions are associated with late decelerations
Umbilical artery doppler is done with
suspicion of fetal growth restriction
Which of the following defines a POSITIVE contraction stress test?
If more than 50% of induced contractions are associated with late decelerations in the fetal heart rate over 10 minutes
What are the 4 types of abortions before 20 weeks gestation?
- Threatened
- Incomplete
- Inevitable
- Missed
How is threatened abortion managed?
- Expectant management
- medical care if vaginal bleeding or pelvic pain
- Rhogham if RH negative
How is incomplete abortion managed?
- stable patient expectant management medically misoprostol or surgically
- Hemodynamic unstable patient: surgical d&C
How is inevitable abortion managed?
Patients can be managed expectantly or medically or surgically if hemodynamically unstable
How is missed abortion managed?
Can be managed medically or surgically
How is spontaneous or complete abortion managed
should be confirmed by ultrasound and serial beta hcg
What are complications of multiple fetus during pregnancy
- preterm labor
- twin-twin transfusion
- fetal growth restriction
- hypertensive disorders
- anemia
- GD
- malpresentation
- post partum hemorrhage
how often should a women pregnant with multiples have an ultra sounds
every 2 weeks
If embryonic division occurs 4-8 days from conception, what kind of twins are most likely to develop?
Monochorionic/ diamniotic twins
If embryonic division occurs 0-4 days after conception, what kind of twins are most likely to develop?
Dichorionic/ diamniotic twins
f embryonic division occurs in an implanted blastocyte 8-14 days after conceptions, what kind of twins are most likely to develop?
Monochorionic/ monoamniotic twins
In a twin-twin transfusion, which of the following is most likely to be seen in the donor twin?
fetal growth restriction
In what type of twin chronicity is the complication of twin-twin transfusion MOST likely to occur?
Monochorionic/ Diamniotic twins
When should high risk women be screened for GD
- First trimester and again at 24-28 weeks
What are high risk factors for screening women for GD twice?
- History of GD
- Obesity
- Advanced maternal age
- African American-Hispanic
- History of infant with macrosomia
How many values need to be abnormal to screen positive for GD?
2 or more values
Women with GD have a what percent risk of developing diabetes?
15-50% lifetime risk
What is preeclampsia
- blood pressure >140/90 but <160/110
- protein/creatinine ratio of >0.3
- 24 hour urine protein >300
- Absence of severe features
What is pre-eclampsia with severe features?
Blood pressure >160/110 New onset cerebral or visual disturbance pulmonary edema HELLP Syndrome Renal insufficiency
What does HELLP syndrome stand for?
- Hemolysis
- Elevated liver enzymes
- Low platelets
What is eclampsia
- HTN
- Proteinuria
- Seizures
When is delivery recommended for gestational HTN
37 weeks
How is pre-eclampsia with severe features managed/
- Magnesium sulfate
- Antihypertensive medications
- delivery if diagnosed after 34 weeks
How is eclampsia treated?
- Stop seizures and stabilize the patient
2. deliver
Magnesium sulfate is given to pregnant women for women for what reason
- 4 or 6 gram to load 2 g/h
calcium channel blocker
seizure prophylaxis
What is the recommended dose of Alpha methyldopa for treatment of HTN disorders in pregnancy?
250-500 mg management of chronic HTN in pregnancy
What is the recommended dose of Labetalol for management of HTN d/o in pregnancy
100-400 mg beta blocker management of HTN in pregnancy, acute
What is the recommended dose of Nifedipine in pregnant women with HTN?
30-60 mg calcium channel blocker management of HTN in pregnancy, acute
What is the recommended dosage of hydralazine for pregnant women with HTN D/O
5-10 mg acute and chronic management of HTN in pregnancy
smooth muscle relaxer
Maternal side of the placenta is called?
Basal plate
The fetal side of the placenta is called?
Chorionic plate
The anatomy of the placenta is
- Placenta disc
- Membranes
- Three vessel umbilical cord
What are the abnormal placental locations?
- Placenta previa
- placenta accreta
- Placenta increta
- Placenta
Placenta located near or over the cervix?
Placenta previa
Recommended method of delivery if a female has placenta previa
C-section
What is placenta accreta?
Placental trophoblast invade to the myometrium.
absence of nitabuch;s
can be associated with placenta previa
placenta can be difficult to remove at the time of delivery
Placenta increta
Placenta trophoblast invade through the myometrium
How is placenta increta managed?
C section with hysterectomy
Placenta trophoblast are through the serosa
placenta percreta
How is placenta percreta managed
C-section hysterectomy with some placenta left in situ is the usual management
Which of the following placental abnormalities is most associated with antepartum hemorrhage and fetal death
Placental previa
Mentum posterior
chin is facing the ceiling
Can face presentation be delivered vaginally?
no
What is a frank breech
the fetal legs are straight
what are the risk of vaginal delivery with a breech fetus
- Cord prolapse
- fetal head entrapment
- risk of fetal injury and death
What is external cephalic version
done at 37 weeks, clinician turns the fetus manually
Risks associated with external cephalic version
- placental abruption
- rupture of membranes
- cord prolapse
- fetal distress
- fetal hemorrhage
symptoms of placenta previa
- painless vaginal bleeding
- do not perform digital exam
- deliver by c -section
what is placental abruption?
placenta is separated from the uterus
causes of placental abruption
- HTN
- Trauma
- Cocaine or tobacco use
- quick decompression of the uterus
What can cause fetal growth restriction
- pre-pregnancy medical conditions
- substance abuse
- pregnancy related conditions
- multifetal gestation
- infections
How is fetal growth restriction defined?
The estimated fetal weight by ultrasound is less than the 10ᵗʰ percentile for its gestational age
What is the most common infectious cause for fetal growth restriction worldwide?
Malaria
In the case of fetal growth restriction, what other factor must be regularly monitored every three to four weeks in addition to monitoring interval fetal growth?
Amniotic fluid level
What does TORCHES mean
- Toxoplasmosis
- Others-Varicella, Hep B, Hep C, GBS
- Rubella
- CMV
- Herpes, HIV
- Syphillis
Rupture of membranes before 37 weeks of gestation
premature rupture of membranes.
What are the psychiatric disorders associated with pregnancy>
- Post partum blues
- post partum depression
- post partum psychosis
When does post partum usually onset
Birth 2 weeks after delivery
What are risk factors for post partum depression?
- history of depression
- poor social support
- baby has health problems or another child
- Difficulty breast feeding
- Financial difficulties
how many pregnancies does post partum depression occur
15-25%
When is the post partum scale administered?
From 2 weeks after delivery up to a year
What is the treatment for post partum depression
psychotherapy
SSRI’s
Symptoms of post partum depression
visual or auditory hallucinations
What is the treatment for psychosis
treatment under a psychiatrist with antipsychotics
How common is post partum psychosis
less than 1% of pregnancy
When should tocolytics be used?
In the case of preterm premature rupture of membranes prior to 34 weeks gestational for up to 48 hours to allow administration of steroids
Which of the following can be a complication of IV hydration in patients with hyperemesis gravidarum
Worsening thiamine (vitamin B1) deficiency