Obstetrics Flashcards
dx: appendicitis in preggers
graded compression u/s
if U/S not diagnostic you can MRI
tx: DVT in preggers
LWMH
when can you get sheehan syndrome
right after childbirth or even months/years later
tx for acute sheenhan syndrome
IV dexamethasone
then MRI the head to r/o other crap
tx: hyperthyroid for preggers
propylthiouracil 1st trimester
methimazole 2nd, 3rd
tx: lyme in preggers
amoxicillin
why do preggers get GDM?
human placental lactogen (aka chorionic somatomammotropin) increases insulin resistance
how much folic acid for preggers
normal: 0.4 mg
high risk: 4 mg
cord compression tx
corticosteroids
quad screen
triple screen + inhibin A
hCG, unconjugated estriol, AFP, inhibin A
quad screen results: + for Downs
decreased AFP
decreased estriol
increased inhibin
increased hCG
management: screening for downs
low risk can get triple screen
high risk (>35, late prenatal) get quad
if + –> genetic counseling
then offer amniocentesis
pregger: fever, abd pain and sausage shaped mass near umbilicus
septic pelvic pain thrombophlebitis
pregger/laboring: fever, tachy, tender uterus, foul smelling amniotic fluid
chorioamnionitis
post partum pelvic pain, foul smelling lochia
endometritis
vag bleeding 20+ weeks: painless vs painful
painless = placenta previa or vasa previa painful = placental abruption
possible problems with babies from DM moms
resp distress syndrome hypertrophic CM (elevated insulin) hypoglycemia (elevated insulin) hypocalcemia (low PTH) polycythemia (hi EPO) hypomagnesemia (Mg excreted by mom kidneys) hyperbilirubinemia (increased hemolysis)
normal fetal HR
110 - 160
tx for GDM
- lifestyle
2. + insulin or glyburide
most effective dating method first TM
transvaginal sonogram: crown-rump length
diff btwn incomplete and inevitable abortion
inevitable is before passage of tissue , incomplete has some or all tissue passed (both have open os)
management: placenta previa
< 36 wks: conservative, repeat U/S before delivery
> 36 wks: U/S, most –> C-section, ant-marginal –> can try vaginal
diff btwn gestational HTN and preeclampsia
preeclampsia has proteinuria or signs of end organ damage
MC breech
frank (butt presents, hips flexed, knees extended)
tx: low breast milk production
- increase feedings
- metoclopramide (D2 antag)
also make sure shes not on combined OCPs
latent phase of labor
effacement and dilation up to 4 cm
prolonged latent phase
null: > 20
multi: > 14
active phase of labor
eff/dil from 4 - 10 cm
prolonged active phase
null: < 1.2 cm/hr
multi: < 1.5 cm/hr
arrested active phase
no dilation in 2 hrs in active phase
second phase of labor
from 10 cm to delivery
prolonged second phase
null: 2 hrs
multi: 1 hr
third stage of labor
baby out to placenta out
prolonged third stage
> 30 min
shiny, peeling areola (breastfeeding)
candidiasis of nipple
tx: nipple candadiasis
-azole cream on nipple
oral azole for baby (thrush)
MCC mastitis
staph aureus
when can you see a gestational sac (BhCG)
transvag: > 1,500
abdominal: > 6,500
BhCG growth: normal vs ectopic
normal: double/48 - 72 hrs
ectopic: lower
dx: ectopic pregnancy
transvag U/S and serial BhCGs
mgmt: ectopic pregnancy
methotrexate
unstable: surgery
mgmt: preterm labor by dates
34 - 36.6: +/- corticosteroids (betamethasone), PCN if GBS(+)/unknown
32 - 33.6: add tocolytics (indomethacin, nifedipine)
< 32: add magnesium sulfate
why do you give mg sulfate for preterm labor
fetal neuroprotection (eg cerebral palsy)
when to cervical cerclage
cervix < 2.5 cm
mgmt: uterine inversion
immediate manual replacement if can't replace, try uterotonics uterotonics once it's replaced (remove placenta after it's replaced if still attached) if nothing works -- laparotomy
baby complications of DM mom (1st TM)
congenital heart dz
NTD
small L colon
spontaneous abortion
baby complications of DM mom (2/3 TM)
hyperinsulinemia polycythemia (up met demand --> hypoxia) organomegaly hypoglycemia brachial plexopathy, clavicle frx, perinatal asphyxia (macrosomia, shoulder dystocia)
preeclampsia: baby risks
chronic uteroplacental insuff –> growth restriction/LBW
not hypoxia, which is due to acute UPI
preeclampsia: mom risks
placental abruption
DIC
eclampsia
fetal non-stress test: what is a reactive result?
110 - 160 bpm mod variability (6 - 25/min) 2+ accelerations in 20 min (each 15+ high and 15+ s long)
causes of non-reactive non-stress test
fetal sleep (MC)
fetal hypoxia (from UPI)
fetal cardiac abnormalities
fetal neuro abnormalities
mgmt: nonstress test
reactive? great, 20 min is good
nonreactive? extend to 40 - 120 min (feti only sleep 40 min at a time)
all nonreactive need follow up biophysical profile or contraction stress test
causes of fetal tachycardia
maternal fever
maternal hyperTh
meds (terbutaline)
placental abruption
definition of fetal growth restriction
U/S estimated weight < 10th percentile for gestational age
symmetric vs asymmetric fetal growth restriction
symmetric: see it 1st TM; global growth lag
asymmetric: see in 2nd/3rd; head-sparing growth lag
causes of fetal growth restriction
symmetric: chromosome abnorm, congenital infection
asymmetric: UPI, maternal malnutrition
normal preg physio: kidneys
up renal blood flow, GFR, BM permeability –>
down serum BUN, Cr
up renal protein excretion
normal preg physio: heart
fill
normal preg physio: lungs
fill
normal preg physio: blood
fill
normal preg physio: endo
fill
recommended preggo vaccines
Tdap
inactivated flu
Rho(D)
preggo vaccines (for high risk pts)
Hep A/B pneumococcus H flu Meningococcal Varicella-zoster Ig
RFs for uterine atony
prolonged labor
induction of labor
operative delivery
fetal weight > 4000 g
spontaneous abortions with closed os
missed
threatened
complete
empty sac = which spontaneous abortion
missed
Tx: asx bacteriuria in pregnancy
cephalexin
amox-clav
nitrofurantoin
NO cipro/TMP-SMX
when can you quad screen
15 - 22 wks
what preg screening can you do @ 10 wks
cell-free fetal DNA
CVS
PaPP, beta HCG, nuchal translucency
when do you give rhogam
28 - 32 wks < 72 hrs after delivery < 72 hrs after abortion 2nd/3rd TM bleeding CVS/amnio
biggest RF for preterm birth
previous preterm birth
cervix things that increase risk of preterm birth
short cervix
cold knife conization
LEEP (maybe)
laser ablation DOES NOT
mgmt: short cervix (with no previous preterm)
vaginal progesterone
mgmt: short cervix (with previous preterm)
IM progesterone @ 2nd TM
serial TVUS to check for short
short –> cerclage
whats on the biophysical profile (+norm)
continuous observation for 30 min non stress test (reactive) amniotic fluid vol (> 2 x 1 cm) fetal mvmts (> 3) fetal tone (> 1 flex/ext) fetal breathing mvmts (> 1 for > 30 s)
when do you deliver based on biophysical profile
4 or less
fetal demise with limb fractures, hypoplastic thoracic cavity
osteogenesis imperfecta (II)
when can you turn a breech baby
37 weeks to onset of labor
who can’t breastfeed
active TB HIV HSV breast lesions varicella meds/chemo/drugs
preterm labor definition
contractions (making cervical change!) before 37 wks
chorioamnionitis aka
intraamniotic infection
criteria for chorioamnionitis
maternal fever plus 1:
- uterine tenderness
- maternal or fetal tachycardia
- malodorous amniotic fluid
- purulent vaginal discharge
tx: chorioamnionitis
broad spectrum Abx
deliver (accelerate w/ oxytocin)
antipyretics
lactation suppression
avoid nipple stimulation
ice packs
NSAIDs
no binding (mastitis) no bromocriptine
prenatal care: when do you type and screen
initial visit
prenatal care: when do you do the 1 hr GTTT
24 - 28 wks
prenatal care: when do you do HIV/HBsAg/RPR/Chlamydia
initial visit
prenatal care: when do you get the GBS culture
35 - 37 wks
prenatal care: when do you get the Ab screen if shes Rh negative
24 - 29 wks
prenatal care: when do you check her rubella/varicella immunity
initial visit
prenatal care: when do you do a UA
initial visit
pregnancy liver d/os
intrahepatic cholestasis of pregnancy
HELLP
acute fatty liver of pregnancy
3rd TM: itchy papular rash around umbilicus
pruritic urticarial papules and plaques of pregnancy
pregnancy: general pruritus, worse at night, worse on palms/soles
intrahepatic cholestasis of pregnancy
definition of preeclampsia
new onset HTN (>140/+/- >90) @ > 20wks +/-
proteinuria (> 0.3 g in 24 hr or protein/Cr ratio >0.3 or dipstick >/= 1+)
plt < 100,000
Cr > 1.1 or doubling Cr
LFT 2x ULN
Pulm edema
Cerebral/visual sx
McRoberts maneuver complication
mom femoral nerve damage
where is 0 station
midway btwn ischial spines
quick loss of fetal station
think uterine rupture
painless vaginal bleeding upon rupture of membranes
think vasa previa
contraindications for exercise in preg
amniotic fluid leak cervical incompetence multis placenta abruption/previa preeclampsia/gest HTN severe heart/lung dz also no hot yoga
mgmt: eclampsia
mg sulfate
anti-HTN (hydralazine, labetalol…)
deliver
when do you treat moms for GBS
+ test: during labor
unknown and < 37 wks: during labor
mgmt: inevitable abortion
hemo stable: misoprostol, nothing or D+C
hemo unstable: D+C
why can’t you use oxytocin for 1 TM/2 TM abortions
there aren’t many oxytocin receptors on uterus yet
pregnancy: thyroid changes
TG up
thyroxine up –> total thyroid hormone up
free T4 only up a little or none
TSH down (suppressed by hcg and increased T4)
tx: hypothyroidism in preg
up levo 30% when find out pregnant
adjust q month
path: HELLP syndrome
abnormal placentation –> systemic inflammation –> activate coags and complement –> platelet consumption and microangio hemolytic anemia –> liver problems
tx: HELLP
delivery
magnesium (seizure prophylaxis)
anti-HTN
when do you do amnioinfusion
variable decels from cord compression in labor
things that cause up AFP in maternal serum
NTDs
abdominal wall defects (omphalocele, gastroschisis)
multiple gestations
rare: congenital nephrosis or obstructive uropathy
EMB: complex endometrial hyperplasia
think about unopposed estrogen
best emergency contraceptive
copper IUD
which emergency contraceptives can be given > 72 hrs after
copper IUD
ulipristal - less effective than IUD
both up to 120 hrs after
tx: essential HTN during pregnancy
labetalol or methyldopa (1st line)
nifedipine and hydralazine good alternatives
mgmt: prego pt on lithium
taper lithium
tx: recurrent variable decels
maternal repositioning (L lat) amnioinfusion if doesnt work
infertility by age
< 35 you get a year to try
> 35, 6 months
what does hCG do
preserves corpus luteum so that progesterone stays up
mgmt: PPROM
34 - 37 wks: abx, +/- corticosteroids, delivery
< 34 wks, no fetal compromise: abx, corticosteroids, fetal surveillance
< 34 wks, fetal compromise: abx, corticosteroids, delivery
< 32 wks, fetal compromise: above + Mg
time frame: post partum blues
2 wks
late term vs postterm pregnancies
late term: 41 wks
post term: 42+ wks
fetal risks a/w late/post term pregnancies
oligohydramnios meconium aspiration stillbirth macrosomia convulsions
maternal risks a/w late/post term pregnancies
c-section
infection
postpartum hemorrhage
perineal trauma
what to do when you can’t find fetal HR w/ doppler
need absence of fetal cardiac activity on abdominal U/S to confirm fetal demise
what has to be done after a fetal demise
fetal: autopsy; examine placenta/membranes/cord; karyotype/genetics
maternal: Kleihauer-Betke test for fetomaternal hemorrhage; antiphospholipid abs; coag studies
c-section: how long after can you give anti-coags if need
6 - 12 hrs
arrest of active labor
no cervical change for > 4 hrs w/ adequate contractions
no cervical change for > 6 w/o adequate contractions
tocolytics
< 32 wks: indomethacin
32 - 34 wks: nifedipine
why do women get hTN post epidural (+ppx)
block sympathetic nerves –> vasodilation (give IVF before)
fetal malposition vs malpresentation
malposition: relation of presenting part to pelvis
malpresentation: presenting part
optimal fetal position
occiput anterior
optimal fetal presentation
vertex
MCC of arrested 2nd stage
fetal malposition
possible nerve stuff with preeclampsia with severe features
hyperreflexia
RFs shoulder dystocia
macrosomia
maternal obesity/excess weight gained in pregnancy
GDM
post-term
Hep C preggo
give hep A/B vaccines if hasn’t had them
don’t treat (teratogens)
breastfeeding is fine
c-section won’t help
RFs for vertical hep C transmission
HIV co-infection
high viral load
oxytocin toxicity
similar to ADH –> hNa, hTN, tachysystole
hNa –> HA, n/v, seizures
amphetamines in pregnancy risks
FGR, fetal demise
preterm labor
placental abruption
preeclampsia
GDM sugar goals
fasting < 95
1 hr postprandial < 140
2 hr postprandial < 120
mgmt: shoulder dystocia
BE CALM
- Breathe, don’t push
- Elevate hips against abdomen (McRoberts)
- Call for help
- Apply suprpubic pressure
- enLarge vaginal opening (episiotomy)
- Maneuvers
shoulder dystocia maneuvers
deliver posterior arm
rotate 180 (Wood’s corkscrew)
collapse ant shoulder (Rubin)
replace fetal head for c-section (Zavanelli)
wtf is pseudocyesis
psych pregnancy
pregnancy sx, thinks test is +
usually following loss or infertility
contraindications to amnioinfusion
hx of uterine surgery
birth plan with hx of vertical c section or open myomectomy
planned c section @ 36 - 37 wks
laparotomy + hysterotomy if labor earlier