Obstetrics Flashcards
Name 6 common nerve and subsequent peripheral palsies from labor and delivery.
1) Femoral: flexion, abduction, external rotation, decreased patellar reflex
2) Lumbrosacral plexus: foot drop, L5 sensory disturbance
3) Sciatica: lateral below knee sensory disturbance.
4) Myalgia paresthetica: lateral femoral cutaneous nerve. Paresthesia of anterolateral thigh.
5) Obturator: hip adduction, internal rotation, upper inner thigh decreased sensation
6) Peroneal: foot drop
What are 6 common risk factors for postpartum neuropathy.
1) Abnormal presentation
2) Persistent posterior occiput
3) Macrosomia
4) Prolonged second stage of labor
5) Difficult Instrumental delivery
6) Prolonged lithotomy position
What are 14 conditions associated with uterine atony?
1) Multiparity
2) previous hx postpartum hemorrhage
3) uterine leiomyomas/ fibroids
4) multiple gestation
5) macrosomia
6) chorioamnionitis
7) polyhydramnios
8) fetal demise
9) amniotic fluid embolism
10) General anesthesia
11) tocolytic use
12) prolonged labor
13) stimulated labor
14) precipitous labor
List 9 risk factors for amniotic fluid embolism.
1) Older age
2) Race
3) Abnormal placentation
4) Placental abruption
5) Eclampsia
6) Multiple gestation
7) Induction of labor
8) Artificial or spontaneous rupture of membranes
9) Operative delivery
What is the risk of placenta accreta in patients with current placenta previa, in relation to the number of prior cesarean sections?
No previous sections have a risk of 3 % accreta. 1 previous section have a risk of 11 %. 2 previous sections have a risk of 40 %. 3 previous sections have a risk of 61 %. 4 previous sections have a risk of 67 %.
Name 4 pharmacological ways to treat uterine atony, along with its dose, contraindications and side effects.
1) Oxytocin. Dose is 20 to 60 units per liter of intravenous infusion. There are no contraindications. Side effects include decreased systemic vascular resistance and free water retention. There is a short duration of effect.
2) Methylergonovine. Dose is 250 micrograms IM. Contraindications include hypertension, pre eclampsia, and coronary artery disease. Side effects include thromboembolic sequelae, severe nausea and vomiting, and arteriolar constriction. There is a long duration of action. Methylergonovine may be repeated once after 1 hour.
3) 15 Methylprostaglandin F 2 alpha AKA heme abait AKA carboprost. Dose is 250 micrograms IM or intrauterine. Contraindications include reactive airway disease, pulmonary hypertension or hypoxemic patients. Side effects include bronchoconstriction, shivering, elevated temperature and diarrhea. Heme abait can be repeated every 15 minutes up to 2 milligrams total.
4) Prostaglandin E 1 AKA Misoprostol. Dose is 800 to 1000 micrograms per rectum. There are no contraindications. Side effects include shivering, temperature elevation, diarrhea, nausea and vomiting, depression of ventilation, bradycardia, flushing.
Name 4 strategies to treat uterine atony and postpartum hemorrhage.
1) Directed therapy of uterine massage and uterotonic drugs.
2) Non surgical uterine compression which includes bimanual uterine compression, external aortic compression, uterine packing and balloon tamponade.
3) Compression sutures including B lynch, and uterine artery embolization.
4) Artery ligation such as uterine or hypogastric artery. Or hysterectomy (subtotal or total).
Question: Name 7 coagulation factors that increase by at least 50% in pregnancy.
1) Factor 7
2) Factor 8
3) Factor 9
4) Factor ten
5) Factor twelve
6) Fibrinogen AKA factor 1
7) plasminogen
Name 8 coagulation factors and parameters that decrease in pregnancy.
1) Factor eleven
2) Factor thirteen
3) Prothrombin time by 20%
4) PTT by 20%
5) Antithrombin three
6) Platelet count
7) Protein S
8) Protein C
Name 5 hematological alterations in pregnancy.
1) Plasma volume increases 40 to 50 percent.
2) Total blood volume increases 25 to 40 percent.
3) Red blood cell volume increases 20 percent.
4) Hematocrit decreases by 35 percent. This relative anemia of preganancy plateaus at 32 to 34 weeks gestation.
5) Serum cholinesterase activity decreases by 25 percent.
Name the 6 cardiovascular changes of pregnancy.
1) Cardiac output increases by 30 to 50 percent.
2) Stroke volume increases by 20 to 50 percent.
3) Systemic vascular resistance decreases by 50 percent.
4) Left axis deviation is seen in EKG due to upward displacement of the heart.
5) Heart rate increases slightly.
6) Systemic blood pressure decreases slightly.
7) LVEDV goes up
8) PCWP no change
9) PVR decreases 30%
Describe cardiac output, with pre preganancy values as baseline, with respect to the following stages of pregnancy:
1) 1st trimester
Answer: Cardiac output begins to increase by 5 weeks’ gestation and is 35% to 40% above baseline by the end of the first trimester.
2) 2nd trimester
Answer: 50% above non pregnant values.
3) Third trimester
Answer: Same as second trimester, 50% above non pregnant values.
4) Labor
Answer: Cardiac output increases progressively with latent, active and 2nd stages, from 70 to 120% above non pregnant values.
When is the highest cardiac output during pregnancy?
Immediately after birth.
When does cardiac output return to pre labor values?
In 24 hours time.
When does cardiac output return to pre pregnancy values?
Between 12 to 24 weeks time. Heart rate, in comparison, reaches pre pregnancy value by 2 weeks post partum.
When do albumin and other protein levels return to pre pregnant levels?
6 weeks post partum.
When do coagulation factors return to pre pregnant levels?
2 weeks post partum
What are the twelve respiratory changes of pregnancy?
1) Functional residual capacity decreases by 20 to 30 percent.
2) Expiratory reserve volume decreases by 15 to 20 percent.
3) Residual volume decreases by 20 to 25 percent.
4) Inspiratory reserve volume is increased.
5) Minute ventilation increases by 50 percent.
6) Alveolar ventilation increases by 70 percent.
7) Tidal volume increases by 30 to 50 percent.
8) Oxygen consumption increases by 20 percent.
9) Carbon dioxide production increases by 35 percent.
10) Respiratory rate is slightly increased.
11) Alveolar dead space increases.
12) Minimum alveolar concentration decreases by 32 to 40 percent.
Describe 2 characteristics of renal plasma flow during phases of pregnancy.
1) During second trimester, renal plasma flow is increased by 80%.
2) Renal plasma flow decreases to 50% above nonpregnant baseline by term.
What happens to creatine and GFR during pregnancy?
GFR increases by 50%, while serum creatinine concentration is decreased.
When is the earliest sign of IVC compression during pregnancy?
13 to 16 weeks.
According to the SOGC 2014 pregnancy induced hypertension guidelines, name three partner related risk factors for pre eclampsia.
1) New partner
2) Previous early miscarriage with same partner
3) Little exposure to paternal sperm (IE reproductive technologies)
Name 7 non partner related risk factors for pre eclampsia.
1) Advanced maternal age (more than 40 years).
2) Family history of preeclampsia.
3) History of preeclampsia in previous pregnancy
4) Multiple gestation.
5) Hydatidiform mole
6) Inter pregnancy interval of more than 10 years
Note: black, hispanic racial background is in Chestnut, as is History of placental abruption, intrauterine growth restriction, or fetal death.
According to the SOGC 2014 pregnancy induced hypertension guidelines, name 5 second or third trimester risk factors for pre eclampsia.
1) Gestational hypertension
2) Abnormal AFP, HCG, uterine artery Dopplers
3) Excessive weight gain in pregnancy
4) Infection during pregnancy
5) Intra uterine growth restriction
Name 7 maternal disease related risk factors for pre eclampsia.
1) Obesity.
2) Chronic hypertension.
3) Diabetes.
4) Renal disease.
5) Antiphospholipid antibody syndrome
6) Systemic lupus erythematosus
7) Cocaine and methamphetamine use
Paradoxically, cigarette smoking during pregnancy has been associated with a decreased risk for pre eclampsia.
Name the 4 hypertensive disorders in pregnancy.
1) Gestational hypertension, which is defined as elevated blood pressure after 20 weeks gestation that resolves by 12 weeks post partum.
2) Pre eclampsia, which is defined as the new onset of hypertension and either proteinuria, adverse or severe complications after 20 weeks gestation.
3) Chronic hypertension, which is defined as pre pregnancy blood pressure levels more than one hundred and forty millimeters mercury systolic, or more than ninety millimeters mercury diastolic that fails to resolve after delivery.
4) Pre existing (chronic) hypertension with superimposed pre eclampsia, which is the new onset of proteinuria or sudden increase in hypertension, or the appearance of other manifestations of severe pre eclampsia.
What are 4 physical symptoms of gestational hypertension?
1) dyspnea
2) right upper quadrant pain
3) cerebral disturbance, such as headache, hyperexcitability, coma
4) visual disturbance, such as blurred vision, scotoma, amaurosis
What are 6 clinical signs of gestational hypertension?
1) Oliguria
2) Proteinuria
3) Papilledema
4) Edematous airway
5) Intrauterine growth restriction
6) Hyper reflexia