Obstetrics Flashcards
Semen in miscarriages
Not analyses
Diagnosis of pregnancy
Pregnancy test urine dip
Entropy on caused by
Pregnancy
Pill
Puberty
Fixed, retro verged uterus and tender
Endometriosis
Pcos hormones
Lh:fsh of 3
How many cross units for pph?
6 units of blood
Zoladex
Goserelin
Lhrh agonist
Endometriosis
Non sexually active teen
Mefanamic acid
NSAID
Post menopausal bleeding
Cervical cancer
Endometrial cancer
Endometrial polyp
Strophic vaginitis
Dysmenoorhoe
Endometriosis IUCd Pid Pcos Ovarian cancer Sexual abuse
Deep dyspareunia
Pid
Endometriosis
Ectopic
Ovarian cancer
Post coital bleeding
Polyp Ectoprocta Cervical cancer Infection Torch
Ovarian cancer marker
Ca125
High hCG
Choriocarcinoma
Hyperemesis
Hydatidiform
Give anti d at:
28 and 34 weeks
Indications for anti d
Spontaneous miscarriage after 12 weeks
Bloods raised in pregnancy
Alk phos Fibrinogen Factors 7, 8, 10 Red cell mass D dimer Urea White cell
Syntometrin
Helps uterus contract
Nomal blood pressure
Syntocynin
Helps uterus contract
High blood pressure
Misoprostol
Helps efface the cervix
Used to induce labour or for abortion
(Oxytocin doesn’t help with cervix
Prostaglandin e analogue
Mifepristal
Anti progesterone and anti glucocorticoid
Abortion agent
Helps with labour
Hemabate
Prostaglandin
Used b
In atonic pph
Tibalone
Endometriosis
Hrt
Oestrogen
Danazol
Low oestrogen
High androgen
Endometriosis
Clomiphine
Used in amenorrhea
Stimulates ovulation
Surfactant develops
34/35 weeks
Perinatal mortality
Pregnancy and a week
Neonatal mortality
Day 1-28
Neonatal jaundice
First 24 h
hCG doubles every:
24 hours
Should see a fetal pole with hCG IS
1500
Most effective contraceptive?
Implanon
Fluid restrict in pet
Less than 85ml per hour
Hyperemesis most in
First 12 weeks
Decapaptyl
Gnrh agonist
Ovulation when oestrogen reaches
800-1200 mmol
Ovulation when follicles size
18-25mm
How many days before next period does ovulation happen?
14 days
Follicular phase
9 to 21 days
Contraception for breast feeding
Pop
Contraception for breast cancer
Copper coil
Larc definition
Less than monthly
Parity includes
Any still births after 24 weeks
Primary ammenorhoe age
Over 16
Threshold for pregnancy test
25 or 50 mlU
Booking appointment at
8-12 weeks
Appointments during pregnancy
Booking 10 20 25 28 31 34 36 38 40 41
Cleft on anomaly scan
Can see cleft lip
Cleft palat more difficult
Congenital rubella
eye problems, such as cataracts (cloudy patches on the lens of the eye) deafness heart abnormalities brain damage First 20 weeks
Gestational diabetes
After 20 weeks
Blood test at 28 weeks
Gestational diabetes before
Get ogtt done earlier at 18 weeks
Then again at 28
Pregnancy induced hypertension starts
After 32 weeks
How many women get hypertension in pregnancy?
10%
How many get pet in pregnancy
2-5%
How many get eclampsia?
1%
Control of glucose most important in the first
8-10 weeks
Vitamin a
Potent teratogen
Folic acid
All women should take at least 400 micrograms/day whilst trying to become pregnant and for at least the first three months of pregnancy to reduce the risk of neural tube defects (NTDs).
Avoid sauna
Fetal hyperthermia
Opiate addiction in pregnancy
intrauterine growth restriction and preterm delivery. This contributes to an increased rate of low birth weight and perinatal mortality.
Varicella in pregnancy
In the first 20 weeks of pregnancy, varicella in the mother may cause congenital fetal varicella syndrome. This may cause limb hypoplasia, microcephaly, cataracts, growth restriction and skin scarring.
Increased maternal age
Downs. miscarriage, twins, fibroids, hypertension, gestational diabetes, labour problems perinatal mortality with increasing maternal age.
Hypertension in pregnancy
May be related to increased aldosterone
Hormones in pregnancy
Prolactin levels increase due to maternal pituitary gland enlargement by 50%. This mediates a change in the structure of the mammary gland from ductal to lobular-alveolar.
Parathyroid hormone is increased which leads to increases of calcium uptake in the gut and reabsorption by the kidney. Adrenal hormones such as cortisol and aldosterone also increase.
Hematology pregnancy
During pregnancy the plasma volume increases by 50% and the red blood cell volume increases only by 20-30%.[13] Consequently, the hematocrit decreases on lab value; this is not a true decrease in hematocrit, however, but rather due to the dilution. The white blood cell count increases and may peak at over 20 mg/mL in stressful conditions. Conversely, there is a decrease in platelet concentration to a minimal normal values of 100-150 mil/mL.
Kidney and pregnancy
increase in kidney and ureter size. (GFR) commonly increases by 50%, returning to normal 20 weeks post
Plasma sodium does not change because this is offset by the increase in GFR.
decreased blood urea nitrogen (BUN) and creatinine and glucosuria (due to saturated tubular reabsorption) may be seen.
The renin-angiotensin system is upregulated, causing increased aldosterone levels.
Peurperium
The cardiovascular system reverts to normal during the first 2 weeks. The extra load on the heart from extra volume of blood disappears by the second week.
The vaginal wall is initially swollen, bluish and pouting but rapidly regains its tone, although remaining fragile for 1-2 weeks. Perineal oedema may persist for some days.
After delivery of the placenta, the uterus is at the size of 20-week pregnancy, but reduces in size on abdominal examination by 1 finger-breadth each day, such that on the 12th day it cannot be palpated. By end of puerperium it is only slightly larger than pre-pregnancy.
PPH definition
first 24 hours is primary
minor 500-1l
major is more than a litre
secondary PPH
Bleeding 24 hours-12 weeks. postnatal
4Ts of pph
Atony
Trauma
Tissue
Thrombin
To stimulate uterine contraction we can:
Uterine massage Bimanual compression Syntometrin Oxytocin Misoprosol
Misoprostol type of prostaglandin
PGE1
Hemabate type of prostaglandin
PGE2alpha
What type of suture for uterine compression?
B-Lynch
Other treatments for uterine compression
Rusch balloon
Bakn balloon
Internal iliac ligation
Artery embolization
How long do we let first baby push and what rate should they dilate?
Dilate at .5cm an hour
Push for 2 hours
How long do we let them push if they’ve had a kid and rate of progression?
1cm an hour please
push for 1 hour
Latent phase
3-4cm
Active phase
4cm-8cm
Transition phase
8cm-10cm
Second stage of labour
10cm to delivery to delivery of fetus
third stage of labour
delivery of fetus to delivery of placenta.
We want baby to come out
occiput anterior
brow presentation
possible
face presentation
impossible
Ventouse cups
Silastic
Metal
Omnicup
Where do we put ventouse?
1cm before lambda
Tachycardic fetus
baseline above 160
cocaine patients
induced by medication
infection
Early decels
good
mimic contractions
late decels
BAD not in sync with contraction placenta praevia insufficient praevia decreased uterine blood flow OXYGENATE MUM!
Turn to left to:
reduce pressure on heart and vena caves
also keep bed low
Suction ventouse
omnicup
ventouse
pump to 0.7bar
Use metal ventouse when:
baby is higher up in birth canal
more difficult
baby’s head is deflexed
Wrigleys
WLO
lift out
Neville Barnes
mid/low cavity
Kielland
kelly is spinning
baby is in posterior position
rotation
Pudendal nerve block
Pudendal nerve runs parellel to ischial spines
Degrees of tears
- skin
- muscle
- anal spincter
- Rectum
Pregnancy induced hypertension
after 20 weeks.
Mild, moderate, severe hypertension
140-149/90-99
150-159/100-109
160+/110+
aspirin 75mg for
those at high risk of PET
Previous history/Diabetes/over 40/ CKD/multiple pregnancy
FROM 12 weeks
Chronic hypertension in pregnancy
NO ACE aloud.
advice to stop 2 weeks before pregnancy too
chronic hypertension after pregnancy
daily for the first 2 days after birth
at least once between day 3 and day 5 after birth
as clinically indicated if antihypertensive treatment is changed after birth.
treat gestational hypertension with:
labetolol oral to get under 150/100 from moderate to severe
(no treatment for mild.
Mild hypertension
don’t really do anything different.
Women at high risk of pet
check their amniotic fluid and growth scan again at 28-30 weeks.
Magnesium sulphate
loading dose of 4 g should be given intravenously over 5 minutes, followed by an infusion of 1 g/hour maintained for 24 hours
recurrent seizures should be treated with a further dose of 2–4 g given over 5 minutes.
Barker hypothesis
IUGR and diseases later in life.
causes of iugr
Advanced diabetes
High blood pressure or heart disease
Infections such as rubella, cytomegalovirus, toxoplasmosis, and syphilis
Kidney disease or lung disease
Malnutrition or anemia
Sickle cell anemia
Smoking, drinking alcohol, or abusing drugs
consequences of iugr
Low birth weight
Difficulty handling the stresses of vaginal delivery
Decreased oxygen levels
Hypoglycemia (low blood sugar)
Low resistance to infection
Low Apgar scores (a test given immediately after birth to evaluate the newborn’s physical condition and determine need for special medical care)
Meconimum aspiration (inhalation of stools passed while in the uterus), which can lead to breathing problems
Trouble maintaining body temperature
Abnormally high red blood cell count
maternal mortality
1 day gestation to 42 days after
uk mmr
11/ 100,000
rf for mmr
too old >35
too young 3
puerperal sepsis
group a strep pyogenes
Breech position
may try to adjust but may need C-section
abnormal lie
ECV or C-section
Hormones in labour
Cortisol up
oestrogen up
PGL up
oxytocin up
progesterone down
Order to labour positions of baby
Engagement Descent Flexion of head Internal rotation Extension of head RESTITUTION (45o rotation of head and 45o further external rotation) Delivery of shoulders
risk factors for pet
1st baby (6x) Multiple pregnancy (x3) Family history (x3) Previous history (x7) Obesity Age
Renal in PET
Oliguria
ATN
Liver in PET
right upper quadrent pain
vomiting
hepatic rupture
abnormal liver enzymes
Lungs in PET
pulmonary oedema
Blood in PET
low platelets
DIC
Eclamptic fit can happen
post-partum
when one twin dies we deliver the other at
34 weeks
TRAP sequence
direct anastamosis?
pressure- reverse flow etc.
Treatment for TRAP
laser ablation, bipolar cord diathermy
TRAP levels
- bladder visible.
- bladder not visible.
- abnormal dopplers
- hydrops
- dead
MC deliver from
36 weeks
DC deliver from
37 weeks
actim partus
IGF binding protein
endocervical
Afosiban
inhibits oxytocin
delays labour
foetal fibronectin
posterior fornix
quadruple down’s test
AFP Oestroil bhCG inhibin-A Cut off 1/150
triple test
AFP
Oestriol
beta-hCG
types of pain relief in labour
Gas and air
Pethidine/Diamorphine (takes 20 mins- lasts 2-4h)
Epidural
Perinatal mortlaity
sillbirth and first 7 days
neonatal mortality
first 4 weeks
Prems have what type of lungs?
Saccular
SGA definition
<10th centile
PE on ECG
S1Q3T3 inversion
CTPA in pregnancy
increases breast cancer for mum
V/Q in pregnancy
increases childhood cancer risk.
Lactaction
During lactation, prolactin is the main factor maintaining tight junctions of the ductal epithelium and regulating milk production through osmotic balance
late miscarriage
after 12 weeks before 24 weeks
listeriosis
food poisoning
heart burn from
12 weeks
TTTS
in monotwins
hyperthyroidism
preterms
antiepileptics
NTDs
beta blockers
IUGR
Ideal HbA1c pre-conception
under 43mmol
ogtt for mum
> 7 at 0 hours
>7.8 at 2 hours
Fetal scalp blood monitoring
pH and lactacte
Tocolytic S/C
Terbutaline
Syntometrin contraindicated in:
high blood pressure and heart disease
use oxytocin instead
First line treatment for diabetes
Insulin (if a drug is needed)
Test for IUGR
Urterine artery doppler
First fetal movements
1st timer: 18-20 weeks
2nd timer: 16-18 weeks
Engagement usually happens
36-38 weeks.
Chorionic villus sampling
diagnostic
after 10 weeks
Amniocentesis
after 15 weeks
Triploidy
three of everything!
Present with early PET
Frontal bossing
beta thalassaemia
Achondroplasia
Warfarin in different trimesters
1st. bone and cartilage
2nd. fine
3rd. blood
breast feeding- is ok
Hydatidi
XS vomiting and large for dates
Cleft palate caused by drug
phenytoin
phenytoin gives mums gingival hyperplasia
Hyperemesis and your Hb
Will appear as HIGH hb as you are dehydrated
Amniocentesis can pick up
neural tube defects (raised AFP levels in the amniotic fluid)
chromosomal disorders
inborn errors of metabolism
Hyperemesis complications
Hyperemesis and Wernickes encephalopathy! Mallory-Weiss Tear Central Pontine myelinolysis ATN Small baby, preterm
How much does bp go up for hypertension?
an increase above booking readings of > 30 mmHg systolic or > 15 mmHg diastolic
oligohydramnios
<500ml amniotic fluid=oligohydramnios
Week 32-36
Maternal hyPERthyroidism
-propylthiouracil has traditionally been the antithyroid drug of choice.
-maternal free thyroxine levels should be kept in the upper third of the normal reference range to avoid fetal hypothyroidism
thyrotrophin receptor stimulating antibodies should be checked at 30-36 weeks gestation - helps to determine risk of neonatal thyroid problems
Maternal hyPOthyroidism
thyroxine is safe during pregnancy
serum thyroid stimulating hormone measured in each trimester and 6-8 weeks post-partum
some women require an increased dose of thyroxine during pregnancy
breast feeding is safe whilst on thyroxine
Hyperechogenic bowel
cystic fibrosis
Down’s syndrome
cytomegalovirus infection
Polyhydramnios
2-3 litres