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YEAR 4 O+G > Obstetrics > Flashcards

Obstetrics Flashcards

1
Q

blood tests in ?suspected cholestasis

A

conjugated bilirubin
AST
ALT
ALP
GGT

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2
Q

signs: meconium aspiration

A
  • meconium stained liquor
  • green staining of infant
  • foetal respiratory distress
  • low APGAR score
  • limp infant
  • crackles on auscultation of foetal lungs
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3
Q

tx: meconium aspiration

A
  • suctioning of mouth and nose
  • prophylactic abx
  • O2 administration
  • monitor
  • ventilate in severe cases
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4
Q

antenatal appt schedule: obs

A

10-12 weeks booking clinic - screen for RFs, dating scan and T21
20 weeks - anomaly scan
28,34 and 36 weeks - midwife appts, monitor foetal growth (SFH) and heart
40 weeks - offered stretch and sweep
41+ - offered IoL

24-28 weeks - screen for GDM
28 and 34 weeks - anti-D

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5
Q

obs taken: antenatal appointments

A
  • BP
  • urinalysis
  • SFH
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6
Q

dating pregnancy: antenatal scan

A

<14/40 - CRL (crown rump length) and BPD (biparietal diameter)
>14/40 - head circumference (BPD), abdominal circumference and femur length

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7
Q

standard dose: folic acid

A

400 micrograms

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8
Q

RFs: higher dose folic acid

A

5mg
* previous baby affected by neural tube defect
* either parent with NTD
* stong fhx NTD
* BMI >30
* diabetes
* coeliac
* thalassaemia
* multiple pregnancy
* drugs - antiepileptics

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9
Q

screening: booking scan

A
  • HIV
  • Hep B
  • syphilis
  • blood group
  • Rh status
  • rubella immunity
  • anaema
  • urinalysis for symptomatic bacteriuria
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10
Q

genetic screening: combined test

A

COMBINED TEST - first line and most accurate
USS (nuchal translucency) and bloods (BhCG and PAPP-A)
* 11-14/40

abnormal result (increased risk)
* USS >6mm nuchal translucency
* increased BhCG
* low PAPP-A (pregnancy-associated plasma protein-A)

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11
Q

genetic screening: triple test

A

between 14-20 weeks

ONLY MATERNAL BLOODS
higher risk:
* BhCG high
* AFP loow
* serum oestriol low

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12
Q

genetic screening: quadruple test

A

14-20 weeks

identical to triple test +inhibin-A
higher risk:
* BhCG high
* AFP low
* oestriol low
* inhibin-A high

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13
Q

genetic screening: antenatal diagnostic testing

A

if risk score >1/150 - woman offered testing for karytyping foetal cells

<15/40 chorionic viillus sampling (CVS) - USS biopsy placental tissue
>15/40 amniocentesis - USS aspiration of amniotic fluid (later in pregnancy when safe to take amniotic fluid)

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14
Q

genetic screening: NIPT

A

non-invasive prenatal testing (Harmony testing) - currently private
from >10/40

  • blood test from mother containing foetal DNA from placental tissue
  • not definitive test but gives indication if foetus is affected
  • gradually rolled out as alternative to invasive tesing
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15
Q

growth chart: antenatal care

A
  • personalised on mothers demographics
  • x= fundal height
  • o = estimated weights to scan
  • centile lines show overall trend
  • falling across centile or <2nd centile = USS repeat in 2 weeks
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16
Q

trimesters: anternatal care

A

0-12 weeks first trimester
13-26 weeks second trimester
27 weeks - birth third trimester

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17
Q

foetal movements: anternatal care

A

from 20 weeks until birth

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18
Q

vaccines: antenatal care

A

whooping cough )pertusis) from 16 weeks
influenza in autumn/winter

live vaccines avoided in pregnancy

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19
Q

pregnancy lifestyle advice: antenatal care

A
  • take folic acid from before 12 weeks
  • take vitamin D supplement (10mcg or 400IU daily)
  • avoid vitamin A (liver or pate - teratogenic in high doses)
  • avoid alcohol (foetal alcohol ssyndrome)
  • avoid smoking
  • avoid unpasteurised dairy (listeriosis)
  • avoid undercooked or raw poultry (risk of salmonella)
  • continue moderate excercise but avoid contact sports
  • sex is safe
  • flying increases VTE risk
  • place seatbelt above or below bump (not acorss it)
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20
Q

foetal alcohol syndrome: antenatal care

A

effects greatest in first 3 months - miscarriage, small for dates, preterm delivery and foetal alcohol syndrome)

FAS:
* microcephaly
* thin upper lip
* smooth flat philtrum
* short palpebral siddures (short distance from one side of eye to other)
* learning disability
* behavioural difficulties
* hearing and vision problems
* cerebral palsy

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21
Q

smoking in pregnancy: antenatal care

A
  • foetal growth restriction
  • miscarriage
  • stillbirth
  • preterm labour and delivery
  • placental abruption
  • pre-eclampsia
  • cleft lip/palate
  • sudden infant death syndrome (SIDS)
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22
Q

flying in pregnancy: antenatal care

A

37 weeks single pregnancy
32 weeks in twin

after 28 weeks airlines often require letter from healthcare stating pregnancy going well and no additional risks

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23
Q

LGA: antenatal care

A
  • growth >95th centile

causes:
* constitutional
* obesity
* diabetes

risks:
* birth injury
* hypoglycaemia

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24
Q

def: SGA

A

growth <10th centile
no underlying pathology

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25
Q

causes: SGA

A
  • maternal height/weight
  • ethnicity
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26
Q

rx: SGA

A
  • growth and umbilical artery doppler 2-3 weekly
  • if abnormal - do CTG
  • if CTG ok - continue monitoring
  • if CTG abnormal - deliver
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27
Q

causes: IUGR

A
  • diagnoses: PET, DM, CKD
  • lifestyle: alcohol, smoking, malnutrition
  • infections: CMV, rubella
  • congenital: trisomies, turners, IEM (inborn errors of metabolism)
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28
Q

signs: IUGR

A
  • decreased foetal movements
  • decreased amniotic fluid
  • abnormal umbilical artery doppler - absent or reversed end diastolic flow)
  • abnormal CTG
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29
Q

management: IUGR

A
  • 2 weekly growth scans, doppler and fluid measurement
  • <32/40 and abnormal doppler = daily CTG
  • if CTG abnormal = deliver
  • > 34/40 and abnormal doppler = deliber
  • if delivering preterm - consider corticosteroidss and MgSO4
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30
Q

rx: delivery preterm

A

corticosteroids lungs
MgSO4 neuroprotective

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31
Q

def: hyperemesis gravidarum

A

prolonger vomiting causing dehydration or >5% weight loss
caused by high B-hCG levels

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32
Q

ix: hyperemesis gravidarum (5)

A
  • U+E (K)
  • urinalysis (ketones)
  • FBC
  • bone profile
  • USS
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33
Q

rx: hyperemesis gravidarum (5)

A
  • antiemetics (cyclizine, promethazine, prochlorperazine)
  • fluid replacement
  • pabrinex (wernicke’s)
  • LMWH and TEDS
  • corticosteroids
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34
Q

def: hypertension in pregnancy

A

BP >140/90
* <20/40 - essential HTN
* >20/40 - NO PROTEINURIA gestational HTN
* >20/40 - PROTEINURIA pre-eclampsia

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35
Q

rx: hypertension in pregnancy

A

1st line = labetalol (NOT ASTHMA)
2nd line = nifedepine (asthma)

ACE/ARB contra-indicated in pregnancy

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36
Q

def: pre-eclampsia

A

multi-system disorder
hypertension with proteinuria or end-organ dysfunction or placental dysfunction

triad = hypertension, proteinuria and oedema

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37
Q

high risk: pre-eclampsia

A

1+ RF = take aspirin
* essential/chronic HTN
* previous HTN in pregnancy
* diabetes
* CKD
SLE or anti-phospholipid syndrome

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38
Q

moderate risk: pre-eclampsia

A

2+ RF = take aspirin
FAMOUS
first pregnancy
age >40
multiple pregnancy
obese BMI >30
unusual gap between pregnancies
strong fhx of HTN

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39
Q

symptoms: pre-eclampsia

A
  • headache
  • blurred vision/flashes
  • apigastric/RUQ pain
  • oedema in hands and feet
  • N+V
  • brisk reflexes
  • reduced urine output
  • IUGR
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40
Q

rx: PET

A

1st line labetalol
2x weekly USS (foetus, fluid, doppler)
2-3x weekly bloods = FBC, U+E, LFT and clotting
if BP can’t be stabilised or mother v unwell (risk of eclampsia) - give MgSO4 (until 24 hours post birth or seizure) and deliver
risk of pulmonary oedema - fluid balance and restrict

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41
Q

def: eclampsia

A

IV MgSO4 (and emergency delivery)
cure - removal placenta

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42
Q

complications: pre-eclampsia

A
  • eclampsia
  • HELLP syndrome (haemolysis (low Hb, elevated liver enzymes, low platelets)
  • stroke
  • renal or liver failure
  • pulmonary oedema
  • DIC
  • placental abruption
  • stillbirth
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43
Q

def: obstetric cholestasis

A
  • reduced flow of bile acids from liver (intrahepatic cholestasis)
  • usually develops after 28/40
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44
Q

CAUSE: PBSTETRIC CHOLESTASIS

A
  • increased oestrogen and progesterone levels
  • genetic component
  • more common in south asian ethnicity
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45
Q

symptoms: obstetric cholestasis

A

itching (esp palms and soles)

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46
Q

complications: obstetric cholestasis

A

increased risk stillbirth - planned birth 37/40

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47
Q

ix: obstetric cholestasis

A

LFTs - ALT, AST, GGT and raised bile acids

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48
Q

rx: obstetric cholestasis

A
  • ursodeoxycholic acid
  • emollients (calamine lotion)
  • antihistimines (chlorphenamine)
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49
Q

RFs: GDM

A
  • BMI >30
  • previous hx GDM
  • previous baby >4.5kg
  • ethnic origin - south asian, middle eastern or afro-carribean
  • 1st degree relative with DM
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50
Q

ix: GDM

A
  • screening at booking for RFs
  • screening at 24-28 weeks for RFs
  • likely to develop in 2nd trimester
  • OGTT 26 weeks
51
Q

OGGT: GDM

A

fasting glucose 5.6mmol/l
2hr after glucose 7.8mmol/l

52
Q

rd: GDM

A

if fasting <7mmol/
1st line diet and excercise
2nd line metformin
3rd line insluin

if fasting >7mmol/l
insulin

53
Q

complications: GDM

A
  • stillirth
  • macrosomia
  • polyhydramnios
  • shoulder dystocia
  • hypoglycaemia neonatally
54
Q

postnatal check: GDM

A

6week post natal glucose check (high risk of developing T2DM)

55
Q

pre-existing DM: risks and prophylaxis

A
  • PET - aspirin 75mg from12/40
  • malformations - high dose folic acid 5mg
  • worsening retinopathy - screening at 28/40
  • HbA1c- each trimester
  • neonatal risks - foetal growth monitored closely
56
Q

pre-existing DM: neonatal complications

A
  • macrosomia
  • hypoglycaemia
  • LGA/IUGR
  • RDS
57
Q

rx: pre-existing DM

A
  • stop hypoglycaemics
  • continue metformin
  • start insulin
  • aim for bith 37-39/40
  • sliding scale insulin during labour and birth
58
Q

epilepsy: antenatal

A
  • pre-conception high dose folic acid 5mg
  • lowest dose antiepileptic (stop phenytoin (cleft lip) and sodium valproate (neural tube defects)
  • seizures likely intra-post-partum
59
Q

multiple pregnancy: TTTS

A
  • monochorionic twins
  • placental anastomosis in shared placents
  • donor twin - volume depleated, IUGR, anaemia
  • recipient twin - fluid overload, polycythaaemia, large for dates
60
Q

def: labour abbreviations

A

ROM - rupture of membranes
SROM - spontaneous rupture of membranes
PROM - premature rupture of membranes
PROM - prolonged rupture of membranes (more than 18hrs before delivery)
PPROM - membranes ruputure before onset of labour and before 37 weeks gestation

61
Q

def: prelabour ROM

A

prelabour rupture of membranes >37 weeks

62
Q

rx: PROM

A
  • give women 24 hours to go into labour
  • if labour doesnt start start oxytocinin infusion
63
Q

ix: PROM

A
  • sterile speculum examination
  • 30 mins lying flat - look for pooling in posterior fornix
  • amnisure - assess for presence of amniotic fluid
  • foetal fibronectin - assesses liklihood of going into labour (premature)
  • NEVER DO DIGITAL EXAM
64
Q

rx: PROM

A
  • erythromycin for 10 days or until labour (chorioamnionitis)
  • assess foetus - CTG and USS
  • corticosteroids - 12g betamethasone IM 24 hours apart
  • avoid sex and pools
65
Q

prophylaxis: preterm labour

A
  • vaginal progesterone (cervical length <25mm between 16-24 weeks)
  • cervical cerclage
66
Q

ix: reduced foetal movements

A

foetal movement should be established by 24/40
RFM should always be reported (reduced risk stillbirth)
* doppler assessment of heart beat
* if heartbeat present - CTG monitoring
* if no heartbeat - USS immediately

67
Q

rx: preterm delivery

A

steroids - betamethasone 2x 12mg IM 24 hours apart (matures foetal lungs)
MgSO4 - neuroprotective <12hours before birth
nifepedine - tocolysis can delay delivrey for few hours

68
Q

antepartum haemorrage before 24/40

A

threatened miscarriage

69
Q

antepartum haemorrhage: painless bleeding differentials

A

placenta previa
vasa previa

70
Q

antepartum haemorrhage: painful bleeding differentials

A

placental abruption
uterine rupture

71
Q

def: placenta praevia

A

placenta over internal cervical os

(low-lying when placenta within 20mm of internal cervical os)
diagnosed at 20 weeks at anomaly scan

72
Q

RFs: placenta praevia

A
  • prev C/S
  • prev placenta praevia
  • older maternal age
  • maternal smoking
  • structural uterine abnormalities
  • assisted reproduction IVF
73
Q

rx: placenta praevia

A
  • repeat TVUSS at 32 weeks and 36 weeks if present at 32 weeks
  • corticosteroids given between 34 and 35+6 weeks to mature foetal lungs (preterm risk)
  • planned C/S delivery between 36 and 37 weeks
  • blood transfusions
  • intrauterine balloon tamponade
  • uterine artery occlusion
  • emergency hysterectomy
74
Q

def: vasa previa

A
  • foetal vessels exposed and travel across cervical os
  • bleeding at ROM with foetal distress

type I - foetal vessels exposed as velamentous umbilical cord
type II - accessory placental lobe

75
Q

rx: vasa praevia

A

corticosteroids given from 32 weeks
elective C/S 34-36 weeks

76
Q

def: placental abruption

A

placenta separates from uterine wall

77
Q

signs: placental abruption

A
  • painful bleeding
  • woody, tender uterus
  • sudden severe onset and continuous
  • maternal shock and foetal distress
78
Q

rx: placental abruption

A
  • emergency C/S
  • call senior obstetrician, medwife and anaesthetist
  • 2x grey cannula
  • bloods - FBC, U+E, LFT and coag
  • crossmatch 4 units blood
  • fluid and blood resus
  • CTG monitoring of foetus
  • close monitoring of mother
  • anti-D prophylaxis
79
Q

test for foetal and meternal blood mixing

A

Kleihauer

80
Q

def: uterine rupture

A
  • usually during labour in 3rd trimester
  • RF: prev C/S and VBAC
  • acutely unwell mother with abd pain
  • decreased uterine contrations
  • foetal distress
  • emergency C/S
81
Q

labour: 1st stage

A

onset of labour (true contractions) effacement and dilation of cervix to 10 cm
latent 0-3cm, 0.5cm/hr - irregular contractions
active 3-7cm, 1cm/hr - regular contractions
transition 7-10cm, 1cm/hr strong and regular contractions

82
Q

failure to progress: 3Ps

A

passage - cephalopelvic disproportion
passenger - foetal malpresentation
power - in-cordinate contractions

83
Q

contractions: aim

A

3-4 in 10 minutes lasting 60 seconds

84
Q

labour: 2nd stage

A

10cm dilatation until delivery of baby
+/- 1 hour passive
delayed pushing <2hours if nulliparous and <1hr if multiparous

85
Q

labour: 3rd stage

A

delivery of placenta
physiological - up to 60 minutes
active - up to 30 minutes (IM oxytocin and controlled cord contraction)

86
Q

contracindiation: ergometrine

A

HTN and heart disease

87
Q

def: Bishop score

A

assess cervix for IoL or during labour
Pregnancy Can Enlarge Dainty Stomachs
Position of cervix
Consistency of cervix
Effacement of cervix
Dilation of cervix
Station of foetal head

score >8 favourable for IoL
score <6 unfavourable and cervical ripening agents considered

88
Q

diagnosis: onset of labour

A
  • show (mucous plug)
  • rupture of membranes
  • regular, painful contractions
  • dilating cervix O/E
89
Q

def: latent first stage

A

painful contractions and change to cervix with effacement up to dilation of 4cm

90
Q

def: established first stage

A

regular, painful contractions and dilation from 4cm onwards

91
Q

induction of labour options

A

vaginal sweep - offered at 40/40
vaginal prostoglandins - pessary over 24 hours, prostogladin gel (aim to break waters)
cooks balloon/foley catheter - mechanical IoL (aim pressure of balloon dilates cervix, ballon falls out and waters break)
amniotomy and oxytocin - artificial ROM followed by infusion within 2 hours

92
Q

complications: IoL

A

uterine hyperstimulation - >5 contractions in 10 mins or lasting >2mins
maternal in left lateral position, stop oxytocinin infusion, tocolytics (terbutaline) consider fluid bolus

93
Q

eg: tocolytic

A

terbutaline

94
Q

def: PPH

A

primary - first 24 hours
secondary - up to 12 weeks postnatal

95
Q

expected blood loss: labour

A

vaginal <500mls
C/S <1000mls

96
Q

casues: PPH

A

4Ts
tone - uterine atony most common
tissue - reatined placenta or membranes
trauma - check perineum and repair
thrombin - clotting disorder in maternal hx (check coag)

97
Q

visual blood loss estimated

A

bed 1000mls
bed anf floor 2000mls
kidney dish 500mls
inco pad 250 mls
sanitary pad 100mls

98
Q

def: major PPH

A

1000-2000mls

99
Q

def: severe PPH

A

> 2000mls

100
Q

management: PPH

A

uterine massage
oxytocinin/syntometrine IM
ergometrine IM
oxytocinin infusion (40 units in 500ml @125ml/hr)
carboprost (prostoglandin)
misoprostal
tranexamic acid 1g slow IV
bimanual compression and go to theatre

101
Q

surgical rx: PPH

A

intrauterine balloon tamponade
bracing B lynch suture
uterine artery embolisation
hysterectomy

102
Q

rx: PPH protocol

A

activate major haemorrhage protocol
senior obstetrician. midwife and anaesthetics
2 grey cannulas
4 units blood crossmatched
fluid and blood resus as required
insert SRCc
CABCDE
increased risk DIC adn need fibrinogen

103
Q

def: shoulder dystocia

A

bony impaction of anterior shoulder on symphysis pubis causing pressure on brachial pressure

104
Q

complications: shoulder dystocia

A

erbs palsy (C5/6)
PPH
4th degree tear
foetal death

105
Q

def: cord prolapse

A

foetal distress on CTG

106
Q

rx: cord prolapse

A
  • do not handle cord
  • mother on all4s
  • emergency C/S
107
Q

RFs: cord prolapse

A

PPROM abnormal lie
post ROM

108
Q

def: amniotic fluid embolism

A
  • liquor enters maternal circulation causing cardipulmonary arrest
  • around time of birth
  • suddden onset SOB, hypoxia, hypotension, seziures, cardiac arrest
109
Q

meconium stained liquor

A

small amount - light green/yellow - continue labour
equal amount liquor and meconium - darkgreen and foetal istress = immediate delivery
meconium dominates labour - black colour = emergency

110
Q

def: placenta accreta

A

placenta implants on surface of myometrium but not beyond

111
Q

def: placenta increta

A

pacenta attaches deep in myometrium

112
Q

def: placenta percreta

A

placenta invades past myometium and perimetrium ?reaching other organs

113
Q

RFs; placenta accreta

A
  • previous placenta accreta
  • prev endometrial curretage
  • previous C/S
  • multigravida
  • increased maternal age
  • low lying placenta/placenta praevia
114
Q

rx: placenta accreta

A
  • planned delivery 35 - 36+6 weeks with C/S
  • additional maagement - ICU, blood transfusions, uterine surgery, NICU
    after delivery
    1. hysterectomy
  • uterus preserving surgery
  • expectant management
115
Q

RFs; VTE pregnancy

A

smoking
aprity >=3
age >35
BMI >30
reduced mobility
multiple pregnancy
pre-eclampsia
varicose veins
family hx
thrimbophilia
IVF pregnancy

116
Q

prophylaxis: VTE in pregnancy

A

first trimester if 3 RFs
28 weeks if 4+ RFs

117
Q

high risk: VTE in pregnancy

A

40mg or 60mg (below or above 90kg) for 6 weeks post natal

118
Q

intermediate risk: VTE in pregnancy

A

10 days postnatal prophylaxis

119
Q

antenatal infection causing: hydrocephalus, chorioretinitis and hearing impairment in baby with flu like symptoms in mum at beginning of pregnancy

A

Toxoplasma gondii

120
Q

perineal tears: degrees

A

1st degree - tear to superficial perineal skin or vaginal mucosa only
2nd degree - perineal muscles and fascia but anal sphincter intact (episiotomy)
3a - less than 50% thickness external anal sphincter torn
3b - more than 50% thickness external sphincter torn but internal anal sphincter intact
3c - external and internal anal sphincters torn but anal mucosa intact
4th - perineal skin, muscle, anal sphincter and. Anal mucosa torn

121
Q

USS: snowstorm appearance

A

molar pregnancy - high levels BhCG

122
Q

rx: perineal tears

A

1st degree - may not require sutures (no muscle involvement and likely to heal quickly)
2nd - suturing by experienced midwife
3rd and 4th - surgical repair in theatre with broad-spectrum and and laxatives post-op

123
Q

unpasteurised cheese: infection

A

listeria monocytogenes

124
Q

def: McRobert’s manoeuvre

A

macroscomic baby who’s shoulders fail to deliver and retracts
mum in McRobert’s position with hyperflexion and abduction of legs tightly to abdomen to relieve impact of shoulder
suprapubic pressure can also be applied

YEAR 4 O+G (6 decks)

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