Obstetrics Flashcards
What is meant by gravidity?
No. of pregnancies a woman has had
What is meant by parity?
No. of pregnancies that went beyond 28 weeks’ gestation that resulted in delivery
What is meant by “para 2+1”?
Woman has had 2 pregnancies beyond 28 weeks and 1 pregnancy terminated/miscarried before 28 weeks
How do you calculate an estimated date of delivery (EDD) of a baby?
1 year + 7 days after LMP, minus 3 months
What happens to red cell volume during pregnancy and what is the consequence of this?
Red cell volume increases, causing dilution of Hb and a physiological anaemia
Treat with iron supplements
What happens to blood pressure during pregnancy?
High in 1st trimester
Falls in 2nd trimester until about 22 weeks
Steady rise to normal by end of term
High blood pressure should normalise within 6 weeks post-partum
When is a pregnancy test +ve?
9 days post-conception until 20 weeks gestation
Can be positive up to 5 days after miscarriage
When is the booking antenatal visit?
8-12 weeks
When is the dating USS done?
Around 10 weeks
When is the Down’s syndrome nuchal thickness test done?
Can be done with dating scan around 10-11 weeks
When is the anomaly scan done?
18 weeks
When is the first routine check-up antenatal visit?
25 weeks
When may a woman receive anti-D prophylaxis?
28 and 34 weeks’ gestation
When is the triple assessment for Down’s syndrome carried out and what does it measure?
11-13 weeks
Nuchal thickness, bHCG and PAPPA levels
Tricyclics are usually OK to prescribe in pregnancy. True/False?
True
but may have withdrawal effects in the foetus
Which SSRI has the lowest risk for use in pregnancy?
Fluoxetine
Avoid paroxetine
Breastfeeding is contraindicated in those taking psychiatric drugs. True/False?
Generally true, especially citalopram and fluoxetine
Consult psychiatrist for specialist advice
When is lithium most teratogenic in pregnancy?
First trimester
BZD use is contraindicated in pregnancy. True/False?
True
How much folic acid is recommended during pregnancy?
0.4mg until 12th week at least
5mg if increased risk of NTD’s (diabetes, epilepsy, obese)
Radioiodine and carbamazepine are safe in pregnancy. True/False?
False
Contraindicated - use propylthiouracil instead
When should trimethoprim and nitrofurantoin be avoided in pregnancy?
Avoid trimethoprim in the first trimester
Avoid nitrofurantoin in the third trimester
In which trimester is there an increased risk of seizures?
First trimester
Which anti-epileptic drug has the lowest risk in pregnancy?
Lamotrigine
Breastfeeding is safe in those taking anti-epileptics. True/False?
True
Except barbiturates
When should methotrexate be stopped with regards to pregnancy?
3 months before trying to conceive
Why should NSAID’s be avoided in the 3rd trimester?
Can cause premature closure of the ductus arteriosus
Which rheumatological antibodies can cross the placenta and cause congenital heart block?
Anti Ro
Anti La
What should patients with antiphospholipid syndrome take in pregnancy?
Aspirin and enoxaparin from 6-34 weeks’ gestation
When can the uterus typically be first felt in pregnancy?
Around 12 weeks
How is gestation estimated according to symphiseal-fundal height?
Gestation = SFH +/- 2cm
Describe foetal movements during labour
Increased flexion and descent as head enters pelvic cavity
Internal rotation at ischial spines, increased head flexion
Head extension to reach out of vulva
Restitution: shoulders rotate and head externally rotates the opposite way
Lateral flexion to deliver shoulders
Deliver buttocks and legs
Describe the basics of a normal CTG trace
Heart rate 110-160 beats/min
Variability greater than 5 beats/min
2 or more accelerations
What might cause reduced variability on a CTG?
Preterm
Sleeping foetus
Drug effects (BZD, opioids)
Hypoxia
What might cause tachycardia on a CTG?
Maternal fever B-agonists Chorioamnionitis Hypoxia Arrhythmia
What might cause bradycardia on a CTG?
Increased vagal tone of foetus
Heart block
Cord compression
What are late decelerations on a CTG a sign of?
Foetal hypoxia
What does DR C BRAVaDO stand for with regards to a CTG?
Determine Risk Contractions Baseline Rate Accelerations Variability Decelerations Overall impression
Blood pressure should normalise within 6 weeks postpartum. True/False?
True
If not, may indicate chronic hypertension
What is pre-eclampsia?
Triad of pregnancy-induced hypertension, proteinuria and oedema
Occurs after 20 weeks gestation, typically resolves within 10 days postpartum
Describe the pathophysiology of pre-eclampsia
Failure of trophoblastic invasion causes failure of normal vascular remodelling: spiral arteries remain high-resistance low-capacitance vessels, causing endothelial damage and dysfunction
List aetiology/risk factors for pre-eclampsia
Maternal/family history Primiparity Twin/multiple pregnancy IVF, ICSI Short stature Obesity Migraine history Hypertension, renal disease Hydatidiform mole
List clinical features of pre-eclampsia
Headaches Visual disturbance Epigastric/RUQ pain Nausea, vomiting Sudden oedema and weight gain Generalised seizure (eclampsia) HELLP syndrome
What investigations would you do for pre-eclampsia?
Bloods: FBC, U+E, LFT's, urate, coag screen Foetal CTG USS, uterine artery Doppler Urinalysis Regular BP checks
Outline management of pre-eclampsia
Admit if BP rises 30/20 from booking BP, or if 140/90 + proteinuria
Treat if systolic over 160: labetolol, methyldopa, nifedipine, hydralazine
Steroids to promote foetal lung development
MgSO4 if eclampsia (prophylactically can half the risk of eclampsia)
Definitive management: delivery the baby!
If a woman is at increased risk of pre-eclampsia, what can she take during pregnancy?
Aspirin from 12 weeks until birth
List aetiology/risk factors for foetal distress
Prolonged pregnancy or labour
Small foetus
Antepartum haemorrhage
Hypertension, pre-eclampsia
List clinical features of foetal distress
Meconium passage in labour
Foetal tachycardia persistently above 160bpm
Loss of variability, late decelerations on CTG
Outline management of foetal distress
Change maternal position IV fluids Stop syntocinon/tocolytics Foetal blood sample Deliver promptly!
Antepartum haemorrhage is defined as bleeding that occurs when?
After 24 weeks’ gestation
What is placental abruption?
Separation of a normally implanted placenta from the uterus
List aetiology/risk factors for placental abruption
Subsequent pregnancies Pre-eclampsia Smokers Previous C-sections Thrombophilia Cocaine use Trauma Polyhydramnios
List clinical features of placental abruption
Bloody cervix
Painful, tender uterus
Backache
Placental insufficiency leads to foetal anoxia/death
How would you diagnose placental abruption?
Clinical diagnosis
Can do transvaginal USS
Outline management of placental abruption
Deliver - C-section if unstable, NVD if stable
What is placenta praevia?
Implantation of placenta in the lower uterine segment, over or near to the cervical os
Describe minor and major placenta praevia
Minor: not covering os but near it
Major: partially or completely covering os
List aetiology/risk factors for placenta praevia
Multiple pregnancy Prior C-sections Uterine abnormalities (fibroids) Smoking Older mum Twin pregnancy IVF
List clinical features of placenta praevia
Painless bleeding
Non-tender uterus
High presenting part
Outline management of placenta praevia
If less than 2cm from os, do C-section
If more than 2cm from os, consider NVD
Do not examine vagina!
What is placenta accreta?
Placenta invades and adheres to myometrium
Associated with previous C-sections
List clinical features of placenta accreta
Massive bleeding
Pain
Outline management of placenta accreta
C-section delivery
May need to do hysterectomy
What is vasa praevia?
Foetal blood vessels overlie internal cervical os, causing increased risk of tearing of vessels and foetal hypoxia
How would you diagnose vasa praevia?
Colour Doppler USS
What is the most common liver disease of pregnancy?
Obstetric cholestasis
List clinical features of obstetric cholestasis
Pruritis in 2nd half of pregnancy
Usually affecting palms and soles
No rash
Outline management of obstetric cholestasis
Vitamin K to mother and baby
Orsodeoxycholic acid
Induce labour at 37 weeks
What is HELLP syndrome?
Haemolysis, Elevated Liver enzymes, Low Platelets
Complication of pregnancy
List clinical features of HELLP syndrome
Upper abdo pain Jaundice Malaise Vomiting Headache
Describe stage 1 of labour
Period from the onset of regular contractions to full dilation of the cervix
Latent phase: 0-3cm dilation, takes ~6h
Active phase: 3-10cm dilation, takes ~1cm/h
3-4 contractions every 10 mins
Describe stage 2 of labour
Period from complete cervical dilation to delivery of baby
Generally lasts 45m-2h in primip, 15-45m in multip
Mother has urge to push, uses abdo muscles, Valsalva maneuvre
Why is cord clamping delayed after delivery?
Delayed for 60s to increase perfusion and O2 to baby