Obs Emergencies Flashcards

1
Q

What are some obstetric emergencies?

A

Emergencies:

  • Shoulder dystocia
  • Cord prolapse
  • PPH
  • Amniotic fluid embolism
  • Placental abruption/APH
  • Eclampsia
  • Placenta praevia/vasa praevia
  • Uterine rupture, uterine inversion
  • Puerperal pyrexia, sepsis
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2
Q

What are 3 major causes of cardiac arrest in pregnancy?

How would you manage a pregnant lady in cardiac arrest?

A
  • Obstetric haemorrhage
  • Pulmonary embolism
  • Sepsis –> metabolic acidosis + shock

A to E approach

  • > Oxygen, intubate
  • > Aggressive fluid resus
  • > Start CPR, but elevate by 15 degrees to the left side to relieve aortocaval compression
  • > Delivery of baby within 4 minutes, and within 5 mins of CPR at site of arrest –> improves maternal survival and improves return to heart + CO, as well as baby survival but this is secondary to mother
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3
Q

What are the 4Ts and 4Hs for reversible causes of cardiac arrest in adults? What does RCOG add to the list for pregnant women?

A
4 Ts
= Thrombosis (PE/MI)
= Tension pneumothorax
= Toxins
= Tamponade (cardiac)
4 Hs
= Hypoxia
= Hypovolaemia
= Hypothermia
= Hyperkalaemia, hypoglycaemia + other metabolic disturbances

RCOG adds:

  • > Eclampsia
  • > Intracranial haemorrhage
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4
Q

What is uterine inversion? How may these women present and how are they managed?

A

Inversion of the uterus where the funds comes down through the cervix and vagina (incomplete) or until the vaginal introitus (complete)

Presents typically with a large PPH +/- maternal shock and collapse

  • > Johnson’s manouvere - manually place fundus back
  • > Hydrostatic methods i.e. filling the vagina with fluid to inflate the uterus back to its original position
  • > Surgery (laparotomy)
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5
Q

What might suggest uterine rupture in a patient, and when may it occur? What are some other RFs?

A

Obstetric emergency!

Presents with

  • Acutely unwell mother (shock, pain, bleeding)
  • Abnormal CTG
  • Ceasing of uterine contractions in labour –> rupture of myometrium +/- uterine serosa –> significant bleeding and morbidity/mortality

Main RF = previous CS (e.g. VBAC: uterus may get even weaker with excessive pressure such as oxytocin)
Other RFs: uterine surgery, increased BMI, use of oxytocin to stimulate contractions and IOL, high parity

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6
Q

What is an amniotic fluid embolism and how does it occur? What are some RFs for it?

A

Obstetric emergency where amniotic fluid and foetal cells enter the maternal circulation causing cardiorespiratory collapse

  • Rare (2/100,000 births)
  • 5th leading cause of maternal death; PE is leading cause)
  • Cause is unclear but embolism provokes an anaphylactic reaction or complement cascade -> pulmonary artery spasm -> inc PA pressure and RVP -> hypoxic heart damage and death

RFs (although often occurs without these)

  • Increasing maternal age
  • Placenta praaevia/abruption
  • IOL - use of uterotonics
  • CS
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7
Q

How may women present with an amniotic fluid embolism ?

A

Sx:

  • Sudden onset SOB +/- cyanosis
  • Bleeding/DIC
  • Seizures
  • O/E - high RR, high HR, hypotension, pulmonary oedema, uterine atony
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8
Q

How would you Ix a woman with a suspected amniotic fluid embolism?

A

Ix:

  • A to E approach
  • Bloods - FBC, clotting (low plt, high PT/APTT, U&Es, X-match
  • ABG
  • CXR - cardiomegaly, pulmonary oedema
  • ECG - right heart strain, rhythm abnormalities
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9
Q

How would you manage an amniotic fluid embolism? What are the complications + prognosis?

A

Mx:

  • A to E approach (ABC) + refer to ITU
  • Maintain patent airway and high flow O2 (+/- intubate)
  • 2 large bore cannulas and fluid resus
  • Inotropes
  • Correct coagulopathy (FFP, cryoprecipitate, plts, transfuse if needed)
  • Consider delivery +/- hysterectomy

Complications:

  • Death, cardiac arrest, DIC, haemorrhage, ARDS, renal failure
  • Poor prognosis - 25% die within 12h, 75% survive but many mothers and children have sequelae
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10
Q

What is the management of a cord prolapse? What are some RFs?

A

Mx:

  1. Summon senior help and consider CTG monitoring of baby
  2. Prevent further cord compression and perform a digital vaginal exam
    - Elevate presenting part or fill the bladder to reduce pressure on the prolapsed cord
    - Tocolytics (nifedipine, atosiban, terbutaline)
    - Avoid handling the cord as causes cord spasm; if the cord passes the introitus, do NOT push back in but keep warm/moist
  3. Place mother in either ALL FOURS or left lateral position or knee-to-chest (baby will fall back into the uterus)
  4. Delivery ASAP by emergency CS or expedited vaginal delivery (whichever is quicker)

RFs:

  • ARM is a big RF!!
  • Malpresentation
  • Multiple pregnancy
  • Polyhydramnios
  • Macrosomina
  • Placenta praevia
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11
Q

What is placental abruption (APH)? What are some RFs for it? How is an APH defined?

A

Separation of the placenta from the uterine wall before delivery (AFTER 24w)

  • > Bleeding before 24w = miscarriage
  • > 1-2% pregnancies

May be idiopathic or occur secondary to raised pressure on maternal side/mechanical factors –> RFs:

  • > HTN !!
  • > Polyhydramnios
  • > Abdominal trauma
  • > Previous APH
  • > Smoking, cocaine
  • > PPROM

Classifications:
Minor haemorrhage – blood loss less than 50 ml that has settled
Major haemorrhage – blood loss of 50–1000 ml, with no signs of clinical shock
Massive haemorrhage – blood loss greater than 1000 ml and/or signs of clinical shock.

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12
Q

How may women present with placental abruption?

A

Sx:

  • Constant abdominal pain +/- PV bleeding*
  • SUSTAINED contractions
  • Woman may be in shock
  • Abdomen will be hypertonic, ‘woody’ and tender uterus
  • Vaginal exam will show cervical dilation (do NOT do in praevia)
  • Speculum to assess bleeding

*If revealed haemorrhage (80%) however 20% are concealed

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13
Q

What Ix would you consider in suspected placental abruption?

A

Ix:

  • Abdominal exam
  • Vaginal and speculum examination (not bimanual if PP)
  • Bloods - FBC, clotting studies, U&Es, crossmatch, G&S, Kleihauer
  • USS
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14
Q

How would you manage placental abruption (mild vs severe)? What are some complications and prognosis of placental abruption?

A

Mx:
General A-E approach, 2x IV access - bloods, blood products/antifibrinolytics, anti-D

Mild

  • > If preterm and stable, then consider conservative management with close monitoring, steroids and IOL at term
  • > Admit for at least 48h or until bleeding stops - if stable and no foetal distress, consider discharge and f/u for serial growth scans weekly until term
  • > Give Anti-D Ig followed by Kleihauer test (how much foetal Hb is in the mothers blood)

Severe/Unstable:
-> Expedite delivery

Complications:

  • > Maternal = haemorrhage (APH, PPH), DIC, renal failure, “couvelaire uterus”
  • > Foetal = birth asphyxia, death
  • > Mortality in severe abruption = 0.5% maternal and 3.3% foetal
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15
Q

What is the definition of a postpartum haemorrhage (PPH)? Categorisation?

A

Blood loss >500ml in SVD or >1000ml at CS

  • Primary PPH is within 24 of birth
  • Secondary PPH is from 24h to 12w post-birth
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16
Q

What are the causes of PPH? RFs associated with these causes?

A

4 Ts:

  • Tone (70%) = uterine atony is the most common cause; avoid it by giving oxytocin for delivery of placenta. Occurs in 1st 24h due to:
  • -> Overdistended uterus - polyhydramnios, multiple pregnancy, macrosomia
  • -> Uterine muscle exhaustion - prolonged or rapid labour, grand multiparty, oxytocin use, GA
  • -> Uterine anatomy is abnormal - fibroids, placenta praevia, placental abruption
  • -> Intra-amniotic infection - fever, prolonged ROM
  • Trauma (20%) = laceration to vagina, cervix, uterus e.g. episiotomy, haematomas, uterine rupture or inversion
  • Tissue (10%) = retained placental products e.g. blood clots in atonic uterus, GTD, abnormal placentation such as placenta accreta/increta/percreta
  • Thrombin (1%) = existing or acquired coagulopathies e.g. haemophilia, DIC, aspirin use, vWD (commonest)

Secondary PPH causes include endometritis, retained productions, trophoblastic disease and abnormal involution of placental site

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17
Q

How may women present with PPH and what Ix would you do?

A

Sx:
[Primary]
- Shock - high HR, low BP
- Signs of anaemia - breathlessness, pallor
- Abdomen exam shows atonic uterus (above umbilicus)
- Speculum (to exclude trauma)
- Vaginal exam to evacuate clots from the cervix as this inhibits contraction

[Secondary]

  • Abdo exam - tender uterus
  • Speculum to assess bleeding and if the cervical os is open
  • Vaginal exam - uterine tenderness
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18
Q

What is a minor and major PPH?

A

Minor PPH = 500-1000mL blood loss and no signs of shock

Major PPH = >1000ml blood loss or signs of shock

19
Q

How would you manage minor and major PPH? How would you manage a secondary PPH?

A

Minor:

  • > Ensure ABC is fine
  • > Wide bore cannulas –> G&S, FBC, Coagulation screen
  • > Give warmed crystalloid infusion
  • > Obs every 15 mins

Major:
A to E Emergency approach
-> Major - ring emergency buzzer + call for help (senior midwife/obstetrician, haematologist, anaesthetist)
-> ABC and lay the woman flat
-> IV access - bloods and urgent transfusion of blood asap if needed, or warmed crystalloid until available

“BE there in one SEC’

  • > Assess ABC + lay woman flat
  • > Bimanual compression or ‘rub up a compression’ if in theatre
  • > Step 1: M/IV Syntocinon 10U, but if uterine hyper stimulation then give tocolytics
  • > Step 2: IM Ergometrine/ syntometrine - but NOT in asthmatics or HTN
  • > Step 3: IM Carboprost - but NOT in asthmatics
  • > Step 4 [Surgical]: Balloon tamponade e.g. Bakri balloon
  • > Step 5: B-lynch suture to ligate arteries via IR
  • > Step 6: Hysterectomy

Secondary PPH
“In women presenting with secondary PPH, an assessment of vaginal microbiology should be performed (high vaginal and endocervical swabs) and appropriate use of antimicrobial therapy should be initiated when endometritis is suspected”
- May do USS to exclude retained products
- Surgical removal of RP if neccesary

20
Q

What are complications of PPH?

A

Complications:

  • Death (leading cause of maternal death worldwide, 4th in UK)
  • Hysterectomy
  • VTE
  • Hypopituitarism (Sheehan’s syndrome)
  • DIC
21
Q

What is an emergency that may occur during delivery of the baby? How would it present, RFs and how is it managed? What is are complications of it?

A

Shoulder dystocia - where shoulder is stuck and cannot delivery baby –> foetal hypoxia

RFs = macrosomnia, high maternal BMI, DM and prolonged labour (also IOL)

Sx:

  • Difficult face/chin delivery
  • ‘Turtling’/retracting head
  • Failure of restitution
  • Failure of shoulder descent

Mx = should all be done within 5 minutes
1. Call for senior help and discourage pushing
2. McRobert’s manœuvre - place woman FLAT and raise legs up to abdomen and suprapubic pressure applied (90% success)
3. Evaluate for episiotomy
4. Either (dep. on experience/indication):
–> Rubin’s manœuvre - push anterior shoulder towards baby’s chest, reducing diameter of the girdle
–> Wood’s screw - Rubin’s + push posterior shoulder towards baby’s back –> rotation
–> Deliver posterior arm then rotate 180 and deliver other arm
5. Change position to all fours and repeat the above manouveres
If fails:
6. Only after careful consideration only: symphisiotomy, cleidotomy (break baby’s clavicle) or Zavanelli (head replaced and CS)

Complication of shoulder dystocia = Erb’s palsy (‘waiter’s tip’) due to brachial plexus damage, humeral fractures, perinatal asphyxia

22
Q

What is an ectopic pregnancy and where are they most commonly seen?
What is the cause of it/risk factors?

A

[Gynae emergency]

Pregnancy outside of the uterus (1.1% of all pregnancies)

98% are in the Fallopian tubes but can occur in ovary, broad ligament, abdomen
Of those in the Fallopian tubes, the most commonly ones are in the ampulla however the isthmus is the site with the highest risk of rupture

Caused by damaged tubes e.g.

  • surgery
  • endometriosis
  • previous ectopic pregnancy (10% recurrence)
  • PID/chronic salpingitis/infections, STIs
  • IUD
  • Smoking
23
Q

How may a woman with an ectopic pregnancy present? What would you see O/E?

A

Sx:

  • Abdominal pain (if ruptured = peritonitis)
  • Amenorrhoea (4-10 weeks) + PV bleeding (scanty, dark red blood)
  • *NOTE: woman may or may not know she’s pregnant**
  • Diarrhoea, shoulder tip pain, back pain - due to blood in recesses irritating surrounding organs (diaphragm)
  • Dizziness/Haemodynamic collapse/shock - if ruptured

O/E:

  • Abdominal - Rebound tenderness and guarding
  • Vaginal - cervical excitation, adnexal tenderness +/- mass (avoid bimanual ins ectopic!)
24
Q

What investigations would you do in a woman with a suspected ectopic pregnancy?

A

Ix:

  • PREGNANCY TEST –> Speculum for Os/masses observation –> TVUSS** (if cannot locate the ectopic on the scan + empty uterus, then it is a PUL and you must do serial b-HCG measurements - will go down
  • Bedside - Obs, Abdominal/Vaginal exam, Speculum exam (NO BIMANUAL as risk of rupture), bloods (FBC, clotting, X-match)

TVUSS**

  • will see empty uterus with adnexal mass, may see foetal heartbeat
  • Tubal = ‘bagel’ sign, ‘blob’ sign
  • Cervical = ‘barrel cervix’, below internal Os, -ve sliding sign
25
Q

How would you manage a patient with an ectopic pregnancy? How would you explain this in PACES?

A

Mx:
- 1st step = call gynaecologist on-call

Expectant –> (stable, unsymptomatic patient with falling levels of b-HCG <1000), Size <30mm

Medical –> 1x IM Methotrexate if stable and asymptomatic, normal LFTs/U+Es, b-HCG<1500, ectopic <35mmm
- Can go home and then come back for f/u [repeat bloods - day 4, 7 and once-weekly till -ve], do not drink alcohol, no conceiving for ~6mo due to teratogenic drug and avoid excessive sun exposure (SE = pain, nausea and diarrhoea for few days)

Surgical –> laparoscopic salpingectomy if significant pain, ectopic with foetal HR, adnexal mass >35mm, bHCG>5000 (salpingostomy can be done if contralateral tube damage or infertility - BUT 1/5 require further Tx later)

  • -> +++ anti-D antibody prophylaxis (250iU) if Rh-
  • -> F/u 3w later with pregnancy test; if had salpingostomy then f/u with b-HCG weekly til negative

PACES:

  • explain that where normally the pregnancy is within the womb this is outside the womb
  • therefore, pregnancy is not viable/not compatible with life and will have to be removed (likely will be someone with a ruptured ectopic so requires surgery)
  • doesn’t reduce chances of getting pregnancy in future
26
Q

What should not be used if one has had a laparoscopic salpingectomy?

A

Copper IUD

27
Q

What are some complications of an ectopic?

A
Rupture
Haemorrhage
Death 5/year
Tubal infertility
Psychological sequelae, recurrent ectopic (15%)
28
Q

What is the differences between placenta accreta, increta and percreta? How would you Ix and Mx these and what are some RFs for them?

A

Placenta accreta = strong attachment of the placenta to the uterus but not into muscle wall

Placenta increta = attachment of placenta into the uterine muscle wall

Placenta percreta = attachment of the placenta through the uterine wall

RFs = PREVIOUS CS/uterine surgery, Hx of accreta, endometrial curettage

Ix:

  • TVUSS
  • MRI to assess depth of invasion

Mx:
- Managed delivery at 35-36+6w +/- caesarean hysterectomy (e.g. for percreta)

29
Q

What is placenta praevia? What are the types?

A

Placenta praevia = placenta lies directly over the internal os, defined after 16w but usually found ~20w scan

Low lying placenta = placental edge is <2cm from internal os (on TVUSS)
-> 0.5% pregnancies

PP Types:

  1. Lateral/low lying
  2. Marginal
  3. Partial (part of the placenta is covering the Os)
  4. Complete (placenta completely covers Os)
30
Q

What are some RFs for placenta praevia? How may women with PP present? What is an APH defined as?

A

RFs:

  • Multiple pregnancy
  • Increased maternal age
  • Previous Hx of praevia
  • Previous uterine surgery e.g. CS!
  • IVF has a 6x increased risk
  • Smoking

Sx:

  • > PAINLESS PV BLEEDING in 2nd/3rd trimester
  • > May have signs of shock

APH:
Spotting = Stains, streaking, or spotting of blood
Minor Haemorrhage = Less than 50mL
Major Haemorrhage = 50-1000mL without signs of circulatory shock
Massive Haemorrhage = Greater than 1000mL with or without signs of circulatory shock

31
Q

How would you Ix placenta praevia?

A

Ix:

  • Obs to check if in shock
  • 1st line Dx = TVUSS
  • Bloods - FBC, clotting, G&S, U&Es, LFTs
  • Kleinbauer test if mother is Rh-/Rhesus status (give anti-D)
  • DO NOT do a bimanual
  • CTG to assess for foetal distress
32
Q

How would you manage placenta praevia:
i) seen at 20w scan
ii) PP with bleeding?
What are some complications of PP?

A

Mx:

  • General:
  • -> advise to not have sexual intercourse
  • -> they will have to delivery by CS

Asymptomatic PP/Low lying placenta at 20w scan:

  • Advise to avoid sex
  • Only 10% go on to have low-lying placenta later in pregnancy
  • Rescan at 32w and if still present and grade I/II then rescan at 36w and if still low, recommend CS at 36-37w

PP with bleeding:
- A to E approach with IV access and fluids, continuous CTG monitoring if 27w+
- Admit at least until bleeding has stopped and then 48h after for observation
—> If mother unstable/foetal distress then delivery imminently
–> Mother/baby stable: give steroids and
admit till bleeding stopped, rescan at 36w and consider delivery ~34-36w
- Growth scans and umbilical artery dopplers every 2w

Complications:

  • APH and PPH, hysterectomy, DIC, death is 1/300
  • Foetal IUGR and death
33
Q

What are some PACES counselling points for placenta praevia?

A

PACES:

  • Will require CS
  • Asymptomatic = explain importance of finding (increased risk of bleeding), 90% placentas move from the entrance of the womb and so we will rescan in 32w and see from there. In meantime, avoid sexual intercourse
  • PP and bleeding = admission needed for at least 2 days, if >34w then admission until delivery, explain importance of finding and that foetus must be monitored and prompt delivery will need to be discussed, will require CS and explain risks of delivery (major blood loss so may require a transfusion, may require a hysterectomy)
  • RFs = previous praevia, previous CS, multiple pregnancy, smoking and drug use, advanced maternal age
34
Q

What is vasa praevia and the types?

A

Foetal vessels traverse through the membrane over the internal cervical Os and below foetal presenting part, unprotected by placental tissue or umbilical cord and therefore when baby descends, they can rupture the vessels
Type 1 = velamentous cord insertion in a single or bilobed placenta
Type 2 = foetal vessels running between lobes of placenta with 1/+ accessory lobes

35
Q

What is Benckaiser’s haemorrhage?

A

Haemorrhage of blood when the unprotected vessels are ruptured in vasa praevia

36
Q

How may women with vasa praevia present and what are some RFs for it?

A

Sx:

  • Typical picture = ROM —> Fresh PV bleeding and foetal bradycardia
  • After ROM, the veins alone can’t hold the weight of the baby –> bleeding
  • O/E you can palpate the vessels in the membranes, amnioscope can directly visualise this

RFs:

  • Bilobed placenta or Succenturiate lobes
  • Hx of low-lying placenta in 2nd trimester
  • Multiple pregnancy
  • IVF
37
Q

What Ix and Mx would you do in a woman with vasa praevia? What are some complications + prognosis of vasa praevia?

A

Ix:

  • Foetal CTG and amnioscope(?)
  • Kleihauer test
  • Doppler USS

Mx:
- CS

Complications:

  • No major maternal risk but dangerous to foetus
  • Even small blood loss for the foetus is significant and therefore rapid delivery is required and resus
  • 60% foetal mortality if presenting with haemorrhage but 3% if identified antenatally
38
Q

What are the effects of substance disorder in pregnancy?

i) Alcohol
ii) Smoking
iii) Cannabis

A

Polysubstance use is common, so screen for all + as well as socioeconomic factors and support

Alcohol:

  • More cognitive and behavioural abnormalities
  • -> Miscarriage, stillbirth, infant mortality, congenital abnormalities, LBW, preterm delivery, SGA
  • -> FAS associated with later neurodevelopment abnormalities, cognitive/behavioural change

Smoking:

  • > Placental abruption, increased risk of ectopic
  • > Miscarriage, stillbirth, LBW
  • > SIDS, lung problems

Cannabis:

  • > Preterm labour, LBW, SGA, increased NICU admission
  • > Linked to reduced attention, poorer academic function, behavioural problems later in life
39
Q

What are the effects of substance disorder in

i) Cocaine
ii) Opioids (hint: NAS)

A

Cocaine:

  • > Placental abruption
  • > PROM, preterm birth, SGA, LBW
  • > Methemphetamine also linked with these + IU death, PET and developmental defects

Opioids:

  • > PROM, preterm birth, LBW, SGA
  • > Placental abruption
  • > Respiratory problems, microcephaly
  • > Neonatal abstinence syndrome [NAS] = opiate exposure in utero which triggers postnatal withdrawal syndrome, causing significant morbidity (45-94% infants exposed to opioids)
  • —> Presents with irritability, hypertonia, seizures, feeding difficulties, tremors, emesis, respiratory distress, loose stools
40
Q

What is the management of a stillbirth in a pregnant woman? How may it be detected?

A

Detected on USS –> IUFD (note: passive fatal movements are possible after IUFD and a repeat scan is offered to confirm)

Mx:
Either expectant or IOL offered:
-> Expectant will require close monitoring
-> IOL = oral mifepristone followed by oral/vaginal misoprostol
-> With consent, do. testing of the foetus and placenta + post-mortem to find cause
-> Anti-D prophylaxis if Rh-
-> Dopamine agonists may be used e.g. Cabergoline to suppress lactation after childbirth
-> PSYCHOLOGICAL support, offer counselling

41
Q

How would you counsel an unexpected pregnancy - 3 options? When is abortion allowed?

A

Keep the baby
Adoption
Abortion

Abortion act of 1967:

  • -> <24w:
  • > if affects mothers health MH + PH
  • > affects pre-existing children’s health
  • > causes more harm in mother to continue
  • -> 24w+ :
  • can be allowed if baby is at severe handicap risk
  • mothers life at risk
42
Q

How would you manage a termination of pregnancy? Medical vs Surgical?

A

IMPORTANT: Requires 2 doctors to agree to the TOP

Medical
–> Mifepristone (oral) followed 24-48 hours later by misoprostol (vaginal, buccal or sublingual); can get at GP or family planning clinic
–> Suitable at any gestation
–> Onset of contractions to expel foetus can be painful, simple analgesia recommended
If 0-9 weeks:
- Can be administered at home provided the patient is easy to f/u + safety netted to seek medical attention if necessary - heavy bleeding/fever/odd smell
- Bleeding can last 2w
- Do pregnancy test in 2-3w
If 9+ weeks:
- Should be given in a clinical setting as increased bleeding and discomfort
- Repeated doses of misoprostol usually required every 3h (max 5) to aid expulsion

Special Consideration after 21+6 Weeks: feticide (intracardiac KCl injection) should be given
to eliminate the possibility of aborted foetus showing any signs of life

Surgical:

  • -> Vacuum aspiration (<14w)
  • Gently dilates cervix and vacuum suction to evacuate uterus
  • LA or GA given
  • Pre-treated with misoprostol for the cervix
  • Abx can be given to reduce infection risk (Met)
  • -> Dilation and Evacuation (14w/+)
  • Good cervical dilation required - LA/GA
  • Misoprostol given 3h-pre surgery
  • Contents extracted via aspiration and forceps
  • USS required to confirm evacuation

Also:

  • NSAIDs for pain relief
  • Discuss contraception use and long-acting methods
43
Q

What are the risks of surgical management of TOP?

A

Fail to end pregnancy
Haemorrhage
Infection
Perforation

No effect on reproductive potential or ectopics