Obs and gynae Flashcards
What is the criteria for PCOS?
Must have 2 out of 3 criteria
1) Enlarged polycystic ovaries
2) Menstrual irregularities
3) Hyperandrogenism (androgens increased)
Symptoms for PCOS
Menstrual irregularities - oligomenorrhoea <9 periods/year or amenorrhoea
Hyperandrogenism - hirsutism, acne
Other symptoms - obesity, acanthosis nigricans, alopecia
Investigations for PCOS?
Hormonal blood tests - raised LH and raised LH:FSH ratio
Pelvic USS: 12 or more follicles or increased ovarian volume
Hyperinsulinemia
Mx for PCOS?
Reduce risks - weight loss, statins, stop smoking, healthy diet, exercise, antihypertensive
1st line - Clomiphene induces ovulation
What is an ectopic pregnancy?
Ectopic pregnancy is where fertilised egg implanted outside uterine cavity e.g. fallopian tubes and ovaries
Risk factors for ectopic pregnancy?
Sterilization, smoking, IUD or IUS, maternal age >35
Symptoms associated with ectopic pregnancy?
Missed period, constant lower abdominal pain in RIF/LIF, vaginal bleeding, referred shoulder tip pain
Investigation for ectopic pregnancy?
Transvaginal USS - identifies gestational sac in location
Positive pregnancy test
Serum hCG for confirmation
Mx for ectopic pregnancy?
Unruptured ectopic pregnancy - medical management using methotrexate
Ruptured ectopic pregnancy - laparoscopic salpingectomy to removed affected fallopian tube
What is endometriosis?
Growth of endometrial tissue outside uterus, commonly occurring in ovaries
Symptoms characteristic to endometriosis?
Chronic and cyclical pelvic pain for at least 6 months (associated with menstruation), deep dyspareunia and dysmenorrhoea
Mx for endometriosis?
Manage symptoms e.g. NSAIDs
Hormonal management e.g. GnRH to suppress ovarian function
Surgical management e.g. laparoscopic ablation - destroys endometrial tissue
What is benign ovarian cyst torsion?
Ovarian torsion is a condition where the ovary twists due to an ovarian mass such as a cyst or a tumour. It is more likely to occur with benign tumours.
Presentation for benign ovarian cyst torsion?
Sudden onset severe pelvic pain and palpable mass.
What presentation will show for ovarian cancer?
Abdominal distension and bloating, abdominal pain painless mass.
Investigations for ovarian cancer?
CA-125 tumour marker for ovarian cancer.
If CA-125 raised, do pelvic USS
What contraception reduces risk of ovarian cancer?
COCP reduces risk as fewer ovulations
Where is LH and FSH produced in body and its roles?
FSH stimulated development of follicles.
LH stimulate ovulation
Both are produced in anterior pituitary gland
Where is oestrogen and progesterone produced and its roles?
Oestrogen promotes female characteristics, it is a sex hormone produced by follicles in ovaries and corpus luteun
Progesterone thickens cervical mucus, alters endometrium and produced by corpus luteum.
What is the follicular phase, ovulation day and luteal phase?
Follicular phase day 1-14
Ovulation day 14
Luteal phase day 15-28
Difference between adenomyosis and endometriosis on bimanual examination?
Endometriosis - fixed retroverted uterus, uterosacral ligament nodules
Adenomyosis (endometrial tissue inside uterus) - boggy uterus
Best investigation to diagnose endometriosis?
Laparoscopy