Obs Flashcards
How to assess GESTATIONAL AGE via US?
1st trimester—-> Gestational sac diameter
1st and 2nd—-> Crown rump length
2nd and 3rd—-> Biparietal diameter / head circumference/ femur length
Important point of gestational age assessment
If USG during 2nd and 3rd trimester shows discrepancy between EGA (calculated from 1st trimester crown rump length) and fetal measurements, growth problems should be considered (e.g. fetal macrosomia, fetal growth restriction)
Define Anemia in pregnancy
Anemia in pregnancy defined as: Hb <11 g/dl in 1st and 3rd trimester and <10.5 g/dl in 2nd trimester
What are the risk factors for HYPEREMESIS GRAVIDARUM?
Past hx of HYPEREMESIS GRAVIDARUM
Multiple gestation
Gestational trophoblastic disease
How to manage GESTATIONAL TROPHOBLASTIC DISEASE (GTD)?
D and C
F/u with Contraception and regular monitoring of B-HCG
Name the vaccine given in WOMEN OF CHILDBEARING POTENTIAL
Tdap
Inactivated influenza vaccine
Name the vaccine contraindicated during pregnancy
HPV
MMR
Varicella
Small pox
Intra nasal influenza vaccine
Name the general test done in first prenatal visit
Cervical cytology
Rh type and antibody screen
Cbc
Genetic testing for down syndrome and Cystic fibrosis
Name the the general infectious test done in first prenatal visit
Rubella and Varicella
Urine culture
Syphilis testing and HBV antigen
Chlamydia and HIV testing
Influenza
Consequences of syphilis in pregnancy
Pregnancy effects—–>preterm labor / Intrauterine fetal demise
Fetal effects—->Hepatomegaly and jaundice
H.anemia with low.PLTs
Long bones abnormalities
when to sample and how to t/m Group B.Strep?
Rectovaginal culture at 35-37 weeks gestation
Give Pencillin as a t/m
What are the indications of GBS treatment?
GBS bacteriauria OR UTI during pregnancy
GBS positive within 5 weeks of labor
Prior birth to an infant affected with early onset GBS disease
What are the indications of GBS treatment?part 2
Unknown GBS status status with;;
- less than 37 wk of gestation
- Intra partum fever
- Rupture of aminotic membrane for more than 24 hours
How to manage unvaccinated pregnant women with confirmed rubella exposure?
termination of pregnancy—->if pt do not wish termination—–> treat with IV immuno globulin—benefits unknown
Name the non invasive PRENATAL TESTING FOR FETAL ANEUPLOIDY?
First and 2nd trimester markers(9-13)///(15-20) both are non invasive and non dx
2nd trimester US and Cell free fetal DNA (18-20)///(>10wks)
Name the invasive test PRENATAL TESTING FOR FETAL ANEUPLOIDY
CVS and aminocentesis (10-30)(15-20wks)
Both test dx karo typic abnormalities
What are the indications for cell free fetal DNA testing?
Maternal age more than 35
Abnormal maternal serum screening test
Fetal ANEUPLOIDY on US and past hx
Parental based robertsonian translocation
What are the uses of Cell free fetal DNA TESTING?
Detection of ANEUPLOIDY
Fetal sex determination
Important point of Cell free Fetal DNA testing
Abnormal test: confirmed by chorionic villus sampling in 1st trimester and amniocentesis in 2nd trimester
Pts who do not meet high-risk criteria for cffDNA: can undergo 1st trimester combined test or 2nd trimester quadruple screen
When to Do OGTT test in pregnancy?
All pregnant women should have OGTT at 24-28 wks—high risk pts (e.g. marked obesity, FH od DM) may receive earlier
Risk Factors of CHORIOAMNIONITIS/INTRAAMNIOTIC INFECTION
Prolong labor
Prolong rupture of membrane
Presence of Genital tract pathogen
Internal fetal Or uterine monitoring devices
Triad of CHORIOAMNIONITIS/INTRAAMNIOTIC INFECTION
High grade maternal fever with maternal tachycardia
Malodorous / Purulent AMNIOTIC fluid Or vaginal discharge
Fetal tachycardia with increased WBC count
Maternal::
Uterine atony
Endometritis
PPH
-Neonate
Premature birth
Cerebral palsy
Infection encephalopathy
Name the tests for ANTEPARTUM FETAL SURVEILLANCE
Non stress test
BPP
Contractions stress test
Doppler US of the umbilical artery
When to call Non stress test “REACTIVE”?
HR 110-160 with moderate variability
More than 2 acceleration
When to call Non stress.test “Non Reactive “?
Less than 2 acceleration
Recurrent variable Or late deaccleration
What are the causes of Non Reactive stress test?
Fetal sleep cycle
Fetal hypoxia due to placental insufficiency fetal cardiac or neurologic abnormalities
Important point
FHR accelerations are the product of the fetal sympathetic nervous system, which matures at 26-28 weeks—extremely premature don’t demonstrate accelerations
Name the causes of Antepartum bleeding
Normal labour
Placental abruption / Previa / vasa
Uterine rupture
How to approach antepartum bleeding?
Start with speculum examination followed by TV.US
Triad of Normal labour
Intermittent pain
Contractions
Small amount of bloody tinged mucus (“bloody show”)
What are the risk factors of placental abruption?
Past hx
maternal HTN or Pre eclampsia / eclampsia
Abdominal trauma
Cocaine and tobacco use
How to dx placental abruption?
Clinically
Or
US to rule out P.Previa; would show retroplacental hematoma
What are the risk factors for Placental Previa?
Past hx
Past hx of C-sec Or any uterine surgery
Advance maternal age with multiparity
Smoking
How to manage Placental Previa?
TA.US followed by TV US
Plus
NO intercourse OR Digital vaginal Ex
Require C-Sec as a t/m
Important point
Fetal heart tracing usually unaffected as bleeding is maternal in origin
What are the risk factors of uterine rupture?
Past hx of Uterine surgery
Protracted Or Induced labour
Congenital uterine anomalies
Fetal macrosomia
Triad of Uterine rupture
Per vaginal bleeding with painful abdominal contraction
Loss of fetal station with palpation of fetal parts on abdominal Examination
Cessation of uterine contraction
Important point of Uterine rupture and P.abruption
No uterine contraction in U.RUPTURE
Tachysystole in placental abruption
How to prevent fetal and maternal exsanguination due to U.Rupture?
Prevention of fetal and maternal exsanguination: emergency laparotomy to confirm diagnosis and expedite delivery
Name type of UTERINE surgery in which trial of labour (vaginal delivery) is not contraindicate
Low transverse (Horizontal) C-section
Name type of UTERINE surgery in which trial of labour (vaginal delivery) is contraindicate
Classical C sec(vertical)
Abdominal myomectomy with uterine Cavity entry
Abdominal myomectomy without uterine Cavity entry
How to manage patient with hx of classical cesarean delivery or extensive myomectomy or myomectomy with uterine cavity entry?
Elective C section
If present in labor—>perform urgent laparotomy followed by hysterotomy (for fetus delivery if unruptured) or uterine repair (if rupture occurred)
Triad of Vasa Previa
Painless per vaginal bleeding with rupture of membrane
FHR shows bradycardia Or sinusoidal tracing
Bleeding causing fetal distress
How to dx and manage Vasa Previa?
Gold standard test is antenatal abdominal and transvaginal Doppler USG
Management is C section
What are the risk factors of PLACENTA ACCRETA?
Hx of C-Sec
Myomectomy
h/o dilatation and curettage, maternal age >35
US findings of Placental accreta
Antenatal ultrasound: an irregular or absent myometrial-placental interface and intraplacental villous lakes—typically diagnosed antenatally
Define Stage 1 ARRESTED of labor?
when dilation is >/=6 cm with ruptured membranes and 1 of the following
-No cervical change for >/=4 hours despite adequate contractions
OR
-No cervical change for >/= 6 hours with inadequate contractions
Define ADEQUATE CONTRACTIONS
Contractions summing to >/=200 Montevideo units for >/=2 hours
Define Latent Labor
Painful contractions causing cervical size change
Regular and Increase intensity/ frequency of contractions
Define false labor
No Or mild painful contractions without causing cervical size change
Irregular and weak intensity of contractions
How to manage false labor?
reassure and discharge with routine prenatal care
Define Precipitous labor
fetal delivery that occurs within 3 hours of the initiation of the contractions.
What causing Precipitous labor
risk factor for precipitous labor is multiparity.
It is spontaneous and not caused by oxytoci infusion
What are the S.E of oxytocin?
Low sodium
Low BP
Excessive Uterine contractions (tachysystole)
What are the S.E of EPIDRUAL ANESTHESIA?
Low BP
Depression of cervical spinal cord and brainstem activity
CSF leakage
Triad of CSF leakage due to Epidural ANESTHESIA
Due to dura is inadvertently punctured during epidural
postural headaches that are worse with sitting up
improved with lying down after delivery
Define Preterm labor
regular contractions at <37 wks of gestation that cause cervical dilatation and/or effacement
What are the risk factor of Preterm labor?
Past Hx
Multiple gestation
Short cervical length
Surgery of cervical
Cigarette use
How to Prevent Preterm labor with negative past Hx?
If No Past Hx—>check Cervical length on TVUS—>if normal—>routine pregnancy
If short length—>Vaginal progesterone and Check length till 24 weeks
How to prevent preterm labor with positive past Hx?
Give Progesterone injections and Do check Cervical length on TVUS
If short length—>Cerclage and serial US till 24 weeks
If normal cervix—->check length till 24 weeks
@What are the predictors of Preterm labor?
Short cervix
Positive fetal fibronectin test on 24-33 wk
Important point
Fetal fibronectin (FFN) in vaginal secretions is usually low from 22-33 weeks gestation
an elevated FFN concentration during this period is associated with an increased risk of preterm delivery.
Before and after 22-33 weeks gestation, FFN is normally high and therefore not a useful test
How to manage Preterm labor?
If before 32wk—>steroid / tocolytics
MgSO4 and Abx for GBS
If after 32 but before 33 wk—->same as above except MgSO4
If after 33 wks but before 37 wks—->only ABx for GBS and with OR without steroids
What are the indications of CESAREAN DELIVERY?
Fetal distress indicated by deceleration
Loss of FHR variability (occurs in fetal academia)
Breech presentation
Multiple prior cesarean deliveries
What are the risk factors of Breech presentation?
.
Risk factors:
prematurity
multiparity
multiple gestation
uterine anomalies
fetal anomalies
and abnormal placentation
Important point of ECV
It can be performed between 37 weeks gestation and the onset of labor and has been shown to reduce the rate of cesarean deliveries.
Before doing ECV, make sure no contraindications of VAGINAL delivery
What are the contraindications of ECV?
Indication of C-sec regardless of fetal lie
-placental abnormalities
- Rupture membrane
- Hyperextended neck
- Fetal Or uterine anomaly
- multiple gestation
D/F B/W ECV AND ICV
ECV done in singleton
ICV always in twin baby
How to manage PRETERM BREECH PRESENTATION?
Before 37 but after 34 weeks
Perform C section only.
No use of uterotonic agents
What are the risk factors ofTRANSVERSE LIE
prematurity,
uterine anomalies,
placenta previa
multiple gestations
How to manage TRANSVERSE LIE?
Give Trial of Labor if baby converts into Vertical position
Remain in traverse lie or converts to breech—> ECV (if not CI)—>successful—> trial of labor
unsuccessful ECV or ECV CI—> C.sec
Define SPONTANEOUS ABORTION (SAB)
fetal loss before the 20th week of gestation
How to approach spontaneous abortion?
US of abdomen OR TVUS
Serial B-HCG monitoring
Name the types of miscarriage in which cervix is open
Inevitable
Incomplete
Septic
Name the type of miscarriage in which cervix is closed
Threatened
Complete
Triad of Threatened miscarriage
Per vaginal bleeding with closed cervical Os
No issue in fetal cardiac activity
Expectant management if fetus is alive and repeat US
Triad of missed miscarriage
No vaginal bleeding
closed cervix
No fetal cardiac activity Or Empty sac
Triad of Inevitable miscarriage
Per vaginal bleeding
Open cervix
POC seen or felt at Or above cervical Os
Triad of Incomplete abortion
Vaginal bleeding
Open cervix
POC 50% seen in reproductive tract
Triad of complete abortion
No vaginal bleeding Or very minimal
Closed cervix
No POC left
How to manage Incomplete/ Inevitable and missed miscarriage?
If hemodynamic stable with minimal bleeding—–>Expectant management/ Prostaglandins Or surgical Evacuation
If unstable with heavy bleeding—-> D and C
Important point
Hospitalization and bed rest—not indicated in 1st trimester abortion spontaneous or threatened abortio
Oxytocin infusion—not used in 1st trimester (used in late 2nd or 3rd trimester)
How septic abortion occur?
Retained POC after elective abortion with non sterile technique
Triad of Septic abortion
Prodromal Sxs
Dilated cervix with Purulent Or bloody discharge
Boggy and tender uterus
Pelvic US finding of septic abortion
Retained POC
Increase vascularity
Echogenic material in the cavity
Thick endometrial stripe
How to manage septic abortion?
ABx and IV fluids
Suction curettage
Removal of uterus if no response to ABX OR develop abscess Or signs of clostridial infection
Important point
Misoprostol is a syntheticprostaglandin approved for use with mifepristone to terminate pregnancies of <49 days gestation
Triad of INTRAUTERINE FETAL DEMISE (IUFD)
Death of afetus in utero after 20 wks of gestation
absence of fetal movement and fetal cardiac activity On US
Cause is Unknown in 50% cases