OBGYN - General Flashcards
Define early, variable, and late decels, sinusoidal, prolonged decels. Mechanism for each?
Early = head compression.
Variable = less than 30s from onset to nadir. Not correl w contractions. Cord compression
Late = Decel starts at max contraction. Placental insuff. Can be from tacchysystole
Sinusoidal = blood loss/fetal anemia. Hydrops fetalis risk
“VEAL CHOP”
Prolonged - >2min but less than 10min.
Woman vomiting - name, risk for, when?
Hyperemiss gravidarum. >5% weight loss. Hypoglycemia==ketoacidosis detected in urine. HEMOCONCENTRATION, HYPOCHLOREMIC MET ALK (VOMIT) HCL. HypoK via kidney excretion from to balance loss of OH- (Na/K atpase followed by ROMK).
Abnormal Uterine bleeding - definition and ddx
5 days more than 1pad/2hrs.
Fibroids - painful enlarged masses on uterus.
Endometriosis - menorrhagia
Adenomysosis - bulky tender enlarged uterus
Screenings for STIs. Who, when, tx if +? Some sxs?
Sexually active women <=25 or women w risk factors should have annual screening via PCR (NAAT). Chlam - azith. Gonn - cef AND azith (due to increasing resistance). Empiric = both.
Sxs: asymop (most common), cervicitis, urethritis, perihepatitis.
Risks: PID, ectopic, infert
Woman stops labor - name, definition
Active phase arrest - 6-10cm no change in size for 4hrs w 200unit contractions or 6hrs with inadequate contractions
Contraindicated in Breast Cancer?
Hormone replacement therapy. Also reduce ETOH intake to less than 1/day
Fetal heart rate tracing is called and when? Can work up more doing this test? What does it consist of and points?
Nonstress test - Contractions&FetalHR done if less than 10 kicks felt by mom in 2hrs.
Biophysical profile - NST + Amnoitic volume (oligohydromanios<=5=6/10 is normal
Skin conditions? Gyn/Ob
-Physiological leukoria….
-Lichen Planus - all mucous affected. Pruritic, glassy red-purple lesions with overlaying white lines.
-Lichen Sclerosis - no vaginal invovlemnt White labial lesions. Prepub and peri/postmenopausal women. r/o cancer then superpotent corticosteroids
-Candida intertrigo - think beefy red plaques, s/p steroids, tx clotrimazole oitment.
-Acanthosis nigricans vs melasma
-Hiradentisi suppurative - recurrent/chronic follicular inflam of intertriginous regions. Tx Doxy.
-Granuloatus inquinale = STI klebseilla - painless ulcers no lymph
-Cellulitis - bactrim (TMP-SMX
-Lymphogrnaulmoa vernirum = chlam, painful w/ lymph
-Condylomata acuminata (gen warts) - HPV6/11. Pink/skin colored leasions. VERRUCCOUS growths. Smooth to caulifolower-like gorwths. Tx: Resin, trichloroactic acid, Imiquiomd, cryotherapy/lase/excision.
Condylomata lata (2nd syph) - gray-white lesion on mucousal. SMOOTH.
HSV warts - ulcerative blisters/pustules
OCPs - side effects/risks
SERMs - tx, SEs, risks
HTN, Clots, breakthrough bleeding. Amenorrhea, breast tenderness, nausea/bloating.
Liver disorders - hepatic adenoma, chole & INCREASED triglycerides.
DECREASED risk of ovarian/endo.
INCREASED risk for cervical.
Not weight gain.
SERMs - Tamox, raloxifene. Comp inhibitor of estrogen (mixed antag/ag). Prevention of breast cancer.
Raloxifene - postmenopausal osteo.
SEs: Hot flashes, venous thromboembol, endo hyperplasia/cancer (tamox)
Fetal bradycardia and tachycardia - when?
Brady <110 = tachysystole of uterus, hypothermia, beta-blockers, hypothyroid (fetal), heart-block (anti-RO/SSA, LA/SSB)
Tachycarida >160 = chorioamniotisis (think infection), beta-agonists, hypoerthyroid, fetal tachyarrhythmia
Fetal HR Accelerations - cause, definition, nl amount?
Contractions? - nl
Categories during labor?
From fetus moving around.
minimal<6 - moderate <=25 marked
<32wks = 10bpm inc for 10seconds 2 in 20min
>=32wks = 15bpm for 15, 2 in 20min.
Contractions - normal is 5/10mins.
Tachy = >5/10min
Type I: nl rate, moderate variability, with accels. Not late/variable decels. +/- early. Type III: 1) Sinusiodal pattern. 2) Minimal variability with any of -Recurrent late decels -Recurrent variable -Bradycardia Type II: everything else
Def of PPH? Causes? Tx? Vignettes?
500ml in NSVD, 1000ml in C-section
1) Uterine Atony - boggy uterus - (most common) - Tx with pitocin. Methylergonivine is contraindicated in hx of ecclamp/HTN.
Carboprost - syn PG uterotonic, bronchoconstric & asthma***
2) If 48-72hrs postpartum think coagulopathy like vW disease (factor 5 is procoag).
3) Genital tract laceration
4) uterine rupture
5) retained placenta
Tx - massage, oxytocin, uterotonics, intrauterine balloon tamponade, uterine artery embolization hysterectomy.
RFs: Prolonged/induced labor, Chorioamn, Multip, polyhydramnios, operative delivery
HTN in pregnancy:
definitions? RFs? Tx? Risk for?
HTN crisis: drugs?
How long after preg can you have PreE?
Chronic HTN.
If AKI signs before 20 weeks it is likely nephropathy
——>20weeks—–
GestHTN = >140/90
PreE >140/90 [x2 4hrs apart] & proteinuria (300mg/ml)
PreE w Severe: >160/110 with
-Cerebral/visual disturbances
-2x nl LFTs
-Thrombocytopenia <100K platelets
-renal insuff: Cr>1.1 (or doubling from nl level)
-Pulm Edema
-*note that proteinuria isn’t needed
RFs: Nulliparity, previous PreE, HTN, DM, Coag, Smoking, CKD, BMI, PCOS, Autoimmune, Sickle cell, African american
Tx: Aspirin for high-risk patients. NSAIDs can INCREASE BP*. Labetolol, Hydralazine, Alpha-methyl-dopa, Nifedipine
HTN crisis: 1st line: IV Hydralazine (vasodil), IV labetalol (not in brady, <60bpm), Nifedipine (oral, not in emesis).
AMdopa - too slow acting. Nitro - last resort, avoid if possible dt cyanide byproduct.
Risk for: Seizure HELLP (epigastric, nasuea, HA) ->DIC risk Abruption Stroke AKI ARDS
6weeks post-partum
Diabetes and Preggers
1hr 50g GLucose test <140
check this
Folate amount?
0.4g/day or if NT defect 4g/day
Poor growth - definition, measured,f/u, risk factors?
Fetal growth restriction <10th percentile (<3==severe).
Crown rump length most reliable.
F/u:
BPP getting amnio fluid volume and umbilical cord doppler. NST.
IUGR dx then twice weekly antenatal testing.
DM2 (not DM1), CVD, HTN, CVA, COPD, BMI. Polyhydramios w reverse doppler flow = deliver now
Normal changes in preg: Blood? CV? Pulm? Renal? Uterus? Progesterone?
Blood: 36% volume (47% plasma, RBCs 17%)
CV: increase in CO (inc HR and SV)
Pulm: Physio dyspnea of preg. 15% insp cap from inc TV and insp reserve. Dec of FRC to 80% of nl
Renal: comp met alk
Uterus and R ovarian vein compress ureter causing hydronep (R more than L). Sigmoid colon protects L.
Progesterone is a smooth muscle relaxant - GERD.
Estrogens/OCPs effects?
Bone protective
Increase in TBG (inc in total T4 but not free).
Risk for blot clots, HTN
Molar pregnancy - presentation? Mets?
Snowstorm appearance on TransVUS.
Lungs are most common site - thus get CXR.
Methods to prolong pregnancy: when to use each? and what each does?
“MTS” - mag, tocolytic, steroids
<32wk - Mag & indometacin & Betamethasone
<34wk - Indomethacin & Betamethasone
<37wk - Betamethasone
Magnesium - develops nervous system, prevents CP.
Indometahcin - tocyltic - allows for you to get steroids on board. Renally excreted.
Steroids = lung maturation
Infertility - defintion? Tx?
1 year of trying.
PCOS - get testosterone levels.
Psych meds - anti-DOPA == inc ProLactin. Fix meds before bromocriptine
Ovarian insufficiency - look for antimullerian hormones
Tx - sex 18 days post-mences.
Prolapse thru vagina or incontince -tx?
Time for postpartum urinary retention?
1) Pelvic floor strengthening then 2) Pessary
Inability to void >=6hrs post NSVD
Endocrine disorders
Phenotympic female at birth, no upper ⅓ of vag or rest of female sex organs. With (androgen insensitivity syndrome->test to est. Androgen receptor cannot inhibit boob formation) vs without breasts (Alpha-5reductase, increase masculine features during puberty, )
“blue tinged vaginal protrusion”
Imperofate hymen