OBGYN Flashcards
when would you NOT treat fibroma w uterine artery embolization
pt wanting to get pregnant in future
key difference between uterine fibroid vs endometrial polyp
fibroid= MC in AA, “lumpy”/irregular/enlarged uterus on palpation
endometrial polyp= not palpable
postmenopausal uterine bleeding
endometrial cancer until proven otherwise
post-coital bleeding
MC presentation of cervical cancer
management of post-op fever
expectant - cytokine-mediated, 48 hours post-op
*after 48 hours: CBC, inspection of wound, full rectovaginal exam
first step in management of suspected domestic abuse
ask open-ended and nonjudgmental questions
once abuse is confirmed, then you can provide them with resources for victims
primary ovarian insufficiency
dx/tx
dx:
menopause (1 year w/o menses) in < 40yo + postmenopause range FSH (>40)
tx:
HRT (estrogen)
*risk of osteopenia/porosis without HRT*
increased risk of (three) with E/P combined hormone therapy
breast cancer
ischemic stroke
myocardial infarction
MCC pituitary adenoma
lactotroph adenoma - hyperprolactinemia
absolute contraindication to vaginal delivery with complete breech
absence of easily accessible OR
permanent treatment for severe uterine prolapse
colpocleisis – vaginal walls sewn together
treatment for cystocele vs rectocele
ant vag wall defect - anterior colporrhaphy
post vag wall defect - posterior colporrhaphy
reinforce/strengthen wall
uterine blood supply
aorta -> ovarian a (w/in suspensory ligament of ovary)
internal iliac a -> uterine a + vaginal a
screening indicated for BRCA-1/-2 positive
@ 25yo
1-2 clinical breast exams q1 year
1 mammogram q1 year
@ 30yo
1 MRI q1 year
2 CA-125 q1 year
**everyone should do self breast exam @ 18yo+
safe anti-HTN in pregnancy (4)
methyldopa
CCB- nifedipine
hydralazine
labetalol
what happens to kidneys during preg
inc GFR (renal protection)
when is ASA indicated in preg
when pt has inc risk of preeclampsia
4 steps of puberty in females in order
thelarche
pubarche
growth spurt
menarche
McCune-albright triad
precocious puberty (before 8yo)
fibrous bone dysplasia
cafe-au-lait spots
acceleration definition
< 32 WGA: 10x10
> 32 WGA: 15x15
what to do next when no accelerations?
fetal scalp stimulation
if acceleration occurs, fetal hypoxia/acidosis are ruled out
first step in managing postmenopausal bleeding ALWAYS
endometrial bx
combination vs estrogen-only hormone replacement
combination= women w/ uterus estro-only= women w/o uterus
scarred skin
chorioretinitis
limb hypoplasia
congenital varicella
< 20 WGA
Horner’s syndrome
cataracts
low birth weight
cortical atrophy
microcephaly
when is Tdap given
27-36 weeks
pre-term
< 37 weeks
post-term
> 42 weeks
early-term
37.0 - 38.6
full-term
39.0 - 40.6
late-term
41.0 - 41.6
low birth weight
ventriculomegaly
hearing impairment
periventricular calcification
CMV
PDA
hearing impairment
purpuric/petechial rash
rubella
intracranial calcifications
disseminated purpuric rash
seizure
toxo
anemia
high output heart failure
cardiomyopathy
parvo
inc nuchal translucency
inc NT = inc risk aneuploidy
diagnostic test for chromosomal defect
chorionic villous sampling @ 10-14 weeks
or
amniocentesis @ 15 weeks
painless bleeding in 2nd/3rd trimester
placentra previa
transabdominal U/S, then transvaginal U/S
when is color doppler U/S indicated
placenta accreta (placental villi attached to myometrium instead of decidua)
continuous external fetal cardiotocography indications (3)
suspected growth restriction
maternal T1 DM
preeclampsia
normal fetal heart rate range
110-160 bpm
decelerations
> 15 bpm decrease for > 15 seconds
indicates fetal compromise
early vs late decelerations
early= begin when contraction begins, ends when contraction ends late= begin when contraction peaks, ends after contraction ends
when is MTX indicated for management of ectopic pregnancy
hemodynamically stable
b-HCG < 5,000
no fetal heart tones
when to give second dose of MTX in management of ectopic pregnancy
if beta-HCG difference between day 4 and day 7 is < 15%
> 20 weeks gestation w sudden-onset:
vaginal bleeding
abd pain
back pain
uterine contractions
placental abruption (incomplete or complete separation from decidua)
placenta previa vs. abruption:
diagnostic method
delivery options
digital cervical exam
diagnosis
previa= U/S
abruption= clinical diagnosis, (but would still do U/S during initial workup of > 20 WGA bleeding to rule out PP)
delivery
previa= requires C/S
abruption= does not require C/S
digital exam
previa= abs contraindi
abruption= not contraindi
< 20 WGA
vaginal bleeding
U/S shows viable fetus
threatened miscarriage
< 20 WGA
vaginal bleeding
no abd pain
U/S shows hypo-/an-echoic crescent-shaped area behind fetal membranes
subchorionic hematoma
inc risk of:
abruption,
preterm labor
top three breast masses in women < 30 yo
fibroadenoma= MCC= glandular + fibrous tissue (smooth, rubbery, mobile, solid)
breast cyst
fibrocystic change= luteal phase, caffeine
initial workup for breast mass in
< 30 yo
> 30 yo
< 30= U/S
> 30= U/S + mammo
when is IV iron supplement indicated (3) during preg
2nd or 3rd tri
oral not effective or not tolerated
severe anemia (hgb @ 8-10)
asymptomatic thrombocytopenia in preg
immune thrombocytopenia (ITP)= plt \< 100,000 tx= steroids
initial serum test for PCOS
androgens/testosterone
false vs latent labor
false (braxton hicks)= contractions diminish, < q8 minutes, no cervical change
latent (first stage of active labor)= contractions intensify, > q5 minutes, cervical change
von willebrand dz
prothrombin deficiency
bleeding tendency
factor V leiden mutation
antithrombin III deficiency
clotting tendency
triple test of breast mass
clinical exam
imaging
biopsy
biopsy of choice for breast mass
if solid -> core needle biopsy
if bloody on FNA -> excisional bx
first trimester weeks
weeks 1-13
second trimester weeks
weeks 14-26
third trimester weeks
weeks 27-40
AFP= dec estriol= dec hCG= dec inhibin-a= same
trisomy 18
AFP= dec estriol= dec hCG= inc inhibin-a= inc
trisomy 21
“HI”= high hCG & inhibin
AFP= inc estriol= same hCG= same inhibin-a= same
open neural tube
thyroid in first trimester
estrogen -> inc TBG
hCG mimics TSH -> dec TSH + inc T3/T4
total thyroid hormone= inc
free/active thyroid hormone= unchanged
*similar process w sex hormone binding globulin and androgens/testosterone during preg*
female @ puberty
no ovaries, blind vaginal pouch
normal breasts, no pubic/axillary hair
high serum testosterone
androgen insensitivity syndrome
genotypic male
female
no uterus, shallow vaginal pouch
normal breasts, pubic hair
normal ovaries
normal serum testosterone
mullerian agenesis (mayer-rokitansky-kuster-hauser) geno-/pheno-typic female
anosmia
kallman zero GnRH (zero LH, FSH, testo/estro) XX= primary amenorrhea, no breasts, no pubic hair, normal mullerian structures (vagina, cervix, uterus)
PAP/HPV screening frequency
21-30yo: PAP+HPV q3 years
30-65yo: PAP q3 years, or PAP+HPV q5 years
cold knife colonization of cervix indications (2)
- CIN III
- cervical lesion extending into endocervical canal
pre-eclampsia definition
proteinuria > 0.3g/day
HTN > 140/90
WGA > 20
rib notching on CXR +
BP in UE >>> BP in LE
coarctation of aorta
colposcopy indications (3)
HSIL
LSIL
ASCUS w/ HPV++++
adnexal mass
abnormal uterine bleeding
uterine hyperplasia
granulosa cell tumor produces estrogen (-\> uterine hyperplasia -\> inc risk of endometrioid cancer type I)
cells w scant cytoplasm
coffee bean nuclei
arranged in rosettes w central clearing
call-exner bodies
granulosa cell tumor
clear cell carcinoma of ovary most characteristic risk factor
endometriosis
mittelschmerz
sudden-onset
mid-cycle pain
U/L to ovarian follicle that has ruptured during ovulation
no other acute abd findings (dx of exclusion)
postpartum hemorrhage definition + management
> 500mL blood post-vaginal delivery
> 1,000mL blood post-C/S
MCC= uterine atony (soft/boggy uterus) management= bimanual uterine massage; if unsuccessful, admin oxytocin
PGE1 analog
misoprostol
goserelin, leuprolide MOA
GnRH agonist
indicated for central precocious puberty
umbilical cord prolapse management
immediate C/S
while awaiting delivery, elevate fetal presenting part to reduce pressure in prolapsed cord
MC sign of umbilical cord prolapse
bradycardia
diagnosis of inflammatory breast cancer
diagnostic mammogram and/or U/S
previously normal mammos (develops in 6 months)
large, obstructing genital warts inc risk of
dystocia (large enough to obstruct birth canal)
indication for C/S
parchment-like labia tx
clobetasol
lichen sclerosus
baby with maculopapular rash
“snuffles”
LAD
HSM
hemolysis
treponema pallidum
indication for D&C in pt with prolonged heavy menstrual bleeding
hemodynamic instability (hypotension, hgb < 7) + IV estrogen
in stable pt: combined OCP
MCC irregular bleeding < 21yo
anovulatory cycle= physiologic in adolescents!
(failure to produce corpus luteum, which makes progesterone)
clomiphene citrate
indicated for infertility secondary to PCOS
SERM
endodermal sinus tumors secrete
AFP
dysgerminomas secrete
LDH
choriocarcinomas secrete
hCG
Mullerian malignancies of ovaries secrete
CA-125
histo: glomeruloid structures with nuclei palisading around capillaries
shiller-duval bodies
endodermal sinus tumor aka yolk sac tumor
histo: syncytiotrophoblasts and cytotrophoblasts
choriocarcinoma
ass. w molar preg
histo: central nucleus with cytoplasm around it, “fried egg” like
dysgerminoma in F
seminoma in M