OBGYN Flashcards

1
Q

when would you NOT treat fibroma w uterine artery embolization

A

pt wanting to get pregnant in future

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

key difference between uterine fibroid vs endometrial polyp

A

fibroid= MC in AA, “lumpy”/irregular/enlarged uterus on palpation
endometrial polyp= not palpable

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

postmenopausal uterine bleeding

A

endometrial cancer until proven otherwise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

post-coital bleeding

A

MC presentation of cervical cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

management of post-op fever

A

expectant - cytokine-mediated, 48 hours post-op

*after 48 hours: CBC, inspection of wound, full rectovaginal exam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

first step in management of suspected domestic abuse

A

ask open-ended and nonjudgmental questions

once abuse is confirmed, then you can provide them with resources for victims

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

primary ovarian insufficiency
dx/tx

A

dx:
menopause (1 year w/o menses) in < 40yo + postmenopause range FSH (>40)

tx:
HRT (estrogen)

*risk of osteopenia/porosis without HRT*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

increased risk of (three) with E/P combined hormone therapy

A

breast cancer
ischemic stroke
myocardial infarction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

MCC pituitary adenoma

A

lactotroph adenoma - hyperprolactinemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

absolute contraindication to vaginal delivery with complete breech

A

absence of easily accessible OR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

permanent treatment for severe uterine prolapse

A

colpocleisis – vaginal walls sewn together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

treatment for cystocele vs rectocele

A

ant vag wall defect - anterior colporrhaphy
post vag wall defect - posterior colporrhaphy

reinforce/strengthen wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

uterine blood supply

A

aorta -> ovarian a (w/in suspensory ligament of ovary)

internal iliac a -> uterine a + vaginal a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

screening indicated for BRCA-1/-2 positive

A

@ 25yo
1-2 clinical breast exams q1 year
1 mammogram q1 year

@ 30yo
1 MRI q1 year
2 CA-125 q1 year

**everyone should do self breast exam @ 18yo+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

safe anti-HTN in pregnancy (4)

A

methyldopa
CCB- nifedipine
hydralazine
labetalol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what happens to kidneys during preg

A

inc GFR (renal protection)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

when is ASA indicated in preg

A

when pt has inc risk of preeclampsia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

4 steps of puberty in females in order

A

thelarche
pubarche
growth spurt
menarche

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

McCune-albright triad

A

precocious puberty (before 8yo)
fibrous bone dysplasia
cafe-au-lait spots

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

acceleration definition

A

< 32 WGA: 10x10

> 32 WGA: 15x15

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what to do next when no accelerations?

A

fetal scalp stimulation
if acceleration occurs, fetal hypoxia/acidosis are ruled out

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

first step in managing postmenopausal bleeding ALWAYS

A

endometrial bx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

combination vs estrogen-only hormone replacement

A
combination= women w/ uterus 
estro-only= women w/o uterus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

scarred skin
chorioretinitis
limb hypoplasia

A

congenital varicella
< 20 WGA

Horner’s syndrome
cataracts
low birth weight
cortical atrophy
microcephaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

when is Tdap given

A

27-36 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

pre-term

A

< 37 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

post-term

A

> 42 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

early-term

A

37.0 - 38.6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

full-term

A

39.0 - 40.6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

late-term

A

41.0 - 41.6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

low birth weight
ventriculomegaly
hearing impairment
periventricular calcification

A

CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

PDA
hearing impairment
purpuric/petechial rash

A

rubella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

intracranial calcifications
disseminated purpuric rash
seizure

A

toxo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

anemia
high output heart failure
cardiomyopathy

A

parvo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

inc nuchal translucency

A

inc NT = inc risk aneuploidy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

diagnostic test for chromosomal defect

A

chorionic villous sampling @ 10-14 weeks
or
amniocentesis @ 15 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

painless bleeding in 2nd/3rd trimester

A

placentra previa
transabdominal U/S, then transvaginal U/S

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

when is color doppler U/S indicated

A

placenta accreta (placental villi attached to myometrium instead of decidua)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

continuous external fetal cardiotocography indications (3)

A

suspected growth restriction
maternal T1 DM
preeclampsia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

normal fetal heart rate range

A

110-160 bpm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

decelerations

A

> 15 bpm decrease for > 15 seconds

indicates fetal compromise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

early vs late decelerations

A
early= begin when contraction begins, ends when contraction ends 
late= begin when contraction peaks, ends after contraction ends
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

when is MTX indicated for management of ectopic pregnancy

A

hemodynamically stable
b-HCG < 5,000
no fetal heart tones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

when to give second dose of MTX in management of ectopic pregnancy

A

if beta-HCG difference between day 4 and day 7 is < 15%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

> 20 weeks gestation w sudden-onset:
vaginal bleeding
abd pain
back pain
uterine contractions

A

placental abruption (incomplete or complete separation from decidua)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

placenta previa vs. abruption:
diagnostic method
delivery options
digital cervical exam

A

diagnosis
previa= U/S
abruption= clinical diagnosis, (but would still do U/S during initial workup of > 20 WGA bleeding to rule out PP)

delivery
previa= requires C/S
abruption= does not require C/S

digital exam
previa= abs contraindi
abruption= not contraindi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

< 20 WGA
vaginal bleeding
U/S shows viable fetus

A

threatened miscarriage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

< 20 WGA
vaginal bleeding
no abd pain
U/S shows hypo-/an-echoic crescent-shaped area behind fetal membranes

A

subchorionic hematoma

inc risk of:
abruption,
preterm labor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

top three breast masses in women < 30 yo

A

fibroadenoma= MCC= glandular + fibrous tissue (smooth, rubbery, mobile, solid)
breast cyst
fibrocystic change= luteal phase, caffeine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

initial workup for breast mass in
< 30 yo
> 30 yo

A

< 30= U/S
> 30= U/S + mammo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

when is IV iron supplement indicated (3) during preg

A

2nd or 3rd tri
oral not effective or not tolerated
severe anemia (hgb @ 8-10)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

asymptomatic thrombocytopenia in preg

A
immune thrombocytopenia (ITP)= plt \< 100,000 
tx= steroids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

initial serum test for PCOS

A

androgens/testosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

false vs latent labor

A

false (braxton hicks)= contractions diminish, < q8 minutes, no cervical change

latent (first stage of active labor)= contractions intensify, > q5 minutes, cervical change

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

von willebrand dz
prothrombin deficiency

A

bleeding tendency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

factor V leiden mutation
antithrombin III deficiency

A

clotting tendency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

triple test of breast mass

A

clinical exam
imaging
biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

biopsy of choice for breast mass

A

if solid -> core needle biopsy
if bloody on FNA -> excisional bx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

first trimester weeks

A

weeks 1-13

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

second trimester weeks

A

weeks 14-26

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

third trimester weeks

A

weeks 27-40

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q
AFP= dec 
estriol= dec 
hCG= dec 
inhibin-a= same
A

trisomy 18

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q
AFP= dec 
estriol= dec 
hCG= inc 
inhibin-a= inc
A

trisomy 21

“HI”= high hCG & inhibin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q
AFP= inc 
estriol= same 
hCG= same 
inhibin-a= same
A

open neural tube

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

thyroid in first trimester

A

estrogen -> inc TBG
hCG mimics TSH -> dec TSH + inc T3/T4

total thyroid hormone= inc
free/active thyroid hormone= unchanged

*similar process w sex hormone binding globulin and androgens/testosterone during preg*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

female @ puberty
no ovaries, blind vaginal pouch
normal breasts, no pubic/axillary hair
high serum testosterone

A

androgen insensitivity syndrome
genotypic male

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

female
no uterus, shallow vaginal pouch
normal breasts, pubic hair
normal ovaries
normal serum testosterone

A
mullerian agenesis (mayer-rokitansky-kuster-hauser) 
geno-/pheno-typic female
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

anosmia

A
kallman 
zero GnRH (zero LH, FSH, testo/estro) 
XX= primary amenorrhea, no breasts, no pubic hair, normal mullerian structures (vagina, cervix, uterus)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

PAP/HPV screening frequency

A

21-30yo: PAP+HPV q3 years
30-65yo: PAP q3 years, or PAP+HPV q5 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

cold knife colonization of cervix indications (2)

A
  1. CIN III
  2. cervical lesion extending into endocervical canal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
71
Q

pre-eclampsia definition

A

proteinuria > 0.3g/day
HTN > 140/90
WGA > 20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
72
Q

rib notching on CXR +
BP in UE >>> BP in LE

A

coarctation of aorta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
73
Q

colposcopy indications (3)

A

HSIL
LSIL
ASCUS w/ HPV++++

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
74
Q

adnexal mass
abnormal uterine bleeding
uterine hyperplasia

A
granulosa cell tumor 
produces estrogen (-\> uterine hyperplasia -\> inc risk of endometrioid cancer type I)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
75
Q

cells w scant cytoplasm
coffee bean nuclei
arranged in rosettes w central clearing

A

call-exner bodies
granulosa cell tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
76
Q

clear cell carcinoma of ovary most characteristic risk factor

A

endometriosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
77
Q

mittelschmerz

A

sudden-onset
mid-cycle pain
U/L to ovarian follicle that has ruptured during ovulation
no other acute abd findings (dx of exclusion)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
78
Q

postpartum hemorrhage definition + management

A

> 500mL blood post-vaginal delivery
> 1,000mL blood post-C/S

MCC= uterine atony (soft/boggy uterus) 
management= bimanual uterine massage; if unsuccessful, admin oxytocin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
79
Q

PGE1 analog

A

misoprostol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
80
Q

goserelin, leuprolide MOA

A

GnRH agonist
indicated for central precocious puberty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
81
Q

umbilical cord prolapse management

A

immediate C/S
while awaiting delivery, elevate fetal presenting part to reduce pressure in prolapsed cord

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
82
Q

MC sign of umbilical cord prolapse

A

bradycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
83
Q

diagnosis of inflammatory breast cancer

A

diagnostic mammogram and/or U/S
previously normal mammos (develops in 6 months)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
84
Q

large, obstructing genital warts inc risk of

A

dystocia (large enough to obstruct birth canal)
indication for C/S

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
85
Q

parchment-like labia tx

A

clobetasol
lichen sclerosus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
86
Q

baby with maculopapular rash
“snuffles”
LAD
HSM
hemolysis

A

treponema pallidum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
87
Q

indication for D&C in pt with prolonged heavy menstrual bleeding

A

hemodynamic instability (hypotension, hgb < 7) + IV estrogen

in stable pt: combined OCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
88
Q

MCC irregular bleeding < 21yo

A

anovulatory cycle= physiologic in adolescents!

(failure to produce corpus luteum, which makes progesterone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
89
Q

clomiphene citrate

A

indicated for infertility secondary to PCOS
SERM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
90
Q

endodermal sinus tumors secrete

A

AFP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
91
Q

dysgerminomas secrete

A

LDH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
92
Q

choriocarcinomas secrete

A

hCG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
93
Q

Mullerian malignancies of ovaries secrete

A

CA-125

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
94
Q

histo: glomeruloid structures with nuclei palisading around capillaries

A

shiller-duval bodies
endodermal sinus tumor aka yolk sac tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
95
Q

histo: syncytiotrophoblasts and cytotrophoblasts

A

choriocarcinoma
ass. w molar preg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
96
Q

histo: central nucleus with cytoplasm around it, “fried egg” like

A

dysgerminoma in F
seminoma in M

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
97
Q

histo: eosinophilic/red intracytoplasmic inclusion

A

“reinke crystals”
leydig or sertoli-leydig tumor
secrete testosterone

98
Q

velvety red vulvar lesion w white plaques

A

paget’s dz of bartholin glands

99
Q

DES exposure causes which 3 cancers

A

vaginal adenocarcinoma
embryonal rhabdomyosarcoma
clear cell carcinoma

100
Q

cysts seen in molar pregnancy

A

theca lutein

101
Q

MCC elevated AFP

A

error in gestational age

102
Q

levonorgestrel

A

plan B

103
Q

AE: oral bisphosphonates

A

esophageal burning

104
Q

AE: IV bisphosphonates and denosumab

A

osteonecrosis of jaw

105
Q

vaccines for preg and HIV+

A

Tdap
inactivated influenza
Hep A
Hep B

106
Q

weight gain based on pre-conception BMI

SINGLETON- underweight, normal, overweight, obese

TWINS- normal

A

SINGLETON

UNDERWEIGHT= 28-40lbs

NORMAL= 25-35 lbs

OVERWEIGHT= 15-25lbs

OBESE= 11-20 lbs

TWINS

NORMAL= 37-54 lbs

107
Q

trichloroacetic acid

A

initial tx for condyloma acuminata in preg woman

108
Q

@ 15 WGA, fetal growth: ___ grams/day

@ 20 WGA, fetal growth: ___ grams/day

@ 32-34 WGA, fetal growth: ___ grams/day

A

15 WGA= 5 grams/day

20 WGA= 10 grams/day

32-34 WGA= 15 grams/day (???? unsure)

109
Q

therapeutic abortion < 10 WGA

A

mifepristone + misoprostol

110
Q

therapeutic abortion @ 10-14 WGA

A

D&C

111
Q

therapeutic abortion > 14 WGA

A

D&E

112
Q

bx for solid vs cystic breast mass

A
solid= core needle bx 
cystic= FNA
113
Q

common complication of hysterectomy

A

urinary incontinence

114
Q

mechanism underlying symptoms of menopause

A

hormonal effects of anovulation

115
Q

3 elevated serum markers in acute phase HBV infection

A

HBsAg, HBeAg, anti-HBc IgM

window period= no anti-HBsAg or HBsAg, only anti-HBc

**ON EXAM: cannot have elevated anti-HBsAg and HBsAg at same time

116
Q

conjugated estrogens + progestins

A

turner syndrome

117
Q

leuprolide pre-surgical indication

A

reduce fibroids prior to surgery

118
Q

bromocriptine
cabergolin

A

DA agonists for hyperprolactinemia (d/t microprolactinoma, < 10 mm diameter)

*DA= prolactin-inhibiting factor*

119
Q

when to initiate antiviral therapy in HBV+ mom

A

only when viral load > 1,000 and/or signs of acute liver impairment

telbivudine or tenofovir (tenofovir also tx maternal HIV)

120
Q

most common complication FOR MOM forceps-assisted vaginal delivery

A

perineal laceration

121
Q

holoprosencephaly
single eye (cyclopia) or nose
cystic hyogroma

A

trisomy 13

122
Q

choroid plexus cyst
congenital diaphragmatic hernia
rocker bottom feet
clenched fists
overlapping digits

A

trisomy 18

123
Q

when is gestational DM screened for and why

A

24-28 WGA
placenta produces enough human placental lactogen at this time to cause insulin resistance

124
Q

congenital GnRH deficiency

A

Kallman
amenorrhea + anosmia

125
Q

mullerian agenesis

A

Mayer-Rokitansky-Kuster-Hauser syndrome

126
Q

androgen insensitivity

A

46, XY
x-linked recessive
female external genitalia
no axillary or pubic hair

127
Q

MCC hypergonadotropic hypogonadism

A

turner

128
Q

hypothalamic hypopituitarism

A

female athlete triad

129
Q

pathogenesis of preeclampsia

A

cytotrophoblast cells fail to migrate to spiral arteries -> insufficient spiral artery transformation/expansion @ 18-20 WGA -> PLACENTAL hypoperfusion

130
Q

cervical cytology vs biopsy

A
cytology= pap; ASCUS, LSIL, etc; examines CELLS 
biopsy= CIN I-III, invasive cervical cancer; examines TISSUE
131
Q

initial management of visible lesion on cervix

A

always biopsy (not cytology)

132
Q

tx for syphilis in pregnant pt w PCN allergy

A

PCN desensitization -> IM PCN G
non-preg tx= alt abx (erythromycin, tetracycline)

133
Q

lower pelvic pain + mucopurulent discharge + cervical motion tenderness

A

PID

134
Q

inc estrogen, inc LH, dec FSH

A

PCOS

135
Q

inc LH, inc FSH, dec estrogen

A

turner

136
Q

hyperprolactinoma -> LH, FSH, estro levels?

A

dec LH, dec FSH, dec estrogen

137
Q

dec LH, dec FSH, inc estrogen

A

granulosa-theca tumor, OR
exogenous estrogen

138
Q

when is endometrial bx indicated in pre-menopausal (< 45 yo) - three

A

persistent abnormal uterine bleeding in setting of:

  • obesity or anovulation - unopposed estrogen
  • failure to respond to previous medical tx
  • high risk for endometrial CA
139
Q

three hematologic considerations for heavy menses

A

VWD, plt dysfunction, immune thrombocytopenic purpura

140
Q

next step in managing symptomatic pt with positive 1hr GTT

A

give diagnosis (GDM) + lifestyle modifications

3hr GTT in asymptomatic w pos 1hr GTT

141
Q

first-line med for GDM

A

insulin
second-line is glyburide

142
Q

fasting and 2hr PP glucose cutoff in preg pt

A

normal=
fasting < 95
2hr PP < 120

143
Q

three factors influencing pap testing frequency and/or testing over 65yo

A

hx of HIV/HPV diagnosis
hx of cervical cancer
cervical dysplasia

144
Q

smoking cessation tx

A

buproprion

145
Q

placental abruption w > 50% separation of placenta from uterine wall -> MC complication?

A

DIC

146
Q

MC neonatal complication of vacuum-assisted delivery

A

cephalohematoma -> JAUNDICE

147
Q

medication-induced hirsuitism

A

phenytoin, danazol

148
Q

pregestational (first tri) diabetes causes

A

caudal regression syndrome
endocardial cushion defects and/or VSD

149
Q

gestational (2nd and 3rd tri) diabetes causes

A

diabetic fetopathy (hyperglycemia-induced hyperinsulinemia)

in utero:

  1. macrosomia: insulin acts like growth hormone, using mom’s sugar to build
  2. hypoxia: inc insulin -> inc BMR-> using up all oxygen
  3. polyhydramnios (leading to PPH, cord prolapse, PROM)

neonatally:

  1. hypoglycemia: insulin without mom’s sugars
150
Q

next step in managing PPROM w unknown WGA

A

fetal biometry - estimate WGA in second/third tri
biparietal diameter, femur length, humerus length, abd circumference

151
Q

dating method in first tri

A

CRL

152
Q

HCG produced by ___ cells and peaks at ___

A

trophoblasts; 8-11 WGA

153
Q

four conditions where hx of condition is greatest RF for recurrence

A

ectopic preg
preterm labor
shoulder dystocia
preeclampsia

154
Q

two findings on mammo suspicious for cancer

A
  1. microcalcifications, especially linear (irregular more likely benign)
  2. spiculated, irregular soft tissue mass

A spiculated mass is a centrally dense lesion seen on mammography with sharp lines radiating from its margin.

155
Q

hx suspicious for PID + presenting w mucopurulent discharge and signs of sepsis

A

ruptured tuboovarian (fallopian tube or ovary) abscess - d/t untreated PID - emergent surgery

156
Q

hysterosalpingogram showing uniform uterine filling and symmetric bilateral spillage

A

NORMAL
spillage of dye from fallopian tubes into peritoneum

157
Q

uterine synechiae

A

intrauterine adhesions - when symptomatic= Ashermann syndrome

158
Q

HNPCC (Lynch) inc risk of which cancer

A

endometrioid CA

159
Q

endometriosis inc risk of which cancer

A

ovarian CA

160
Q

bisphosphonate AE

A

esophageal ulcer
esophagitis
osteonecrosis of jaw

161
Q

-dronic acid/-dronate

A

bisphosphonate

162
Q

osteoporosis T-score

A

< -2.5 = osteoporosis

163
Q

prolonged retention of tissue after intrauterine fetal demise ->

A

DIC

164
Q

uterotonics- three

A

misoprostol - PGE1 analog
carbaprost - PGF2-alpha analog - CI in asthma
methylergonovine - ergot alkaloid - CI in HTN

165
Q

lochia

A

superficial endometrial decidua tissue
begins as bloody -> turns pinkish/watery
lasts = 6 weeks PP

166
Q

when can twins undergo trial of vaginal delivery

A

only when DIAMNIOTIC with presenting fetus in VERTEX

167
Q

prevention of transmission to fetus when mom is HBsAg+/IgG anti-HBcAg+ (chronic infection)

A

immediately after birth, baby gets HBV immune globulin & HBV vaccine

168
Q

flunitrazepam
gamma-hydroxybutyrate

A
flunitrazepam= roofie 
gamma-hydroxybutyrate= unspecific date rape drug 

both cause amnesia

169
Q

most important aspect of PE in sexual assault victim

A

photographs!!

170
Q

when to diagnose anemia in preg

A

first/third tri= hgb < 11
second tri= hgb < 10.5

171
Q

RBC & WBC levels in preg

A

RBC increase - MCV increases (young RBCs are largest)
WBC increase - esp neutrophils

172
Q

pregnancy is ___-coagulable state

A

HYPERCOAGULABLE - inc fibrinogen

173
Q

infant with lethargy, temp instability, hypoxia, poor perfusion, hypotension, resp distress

A

neonatal sepsis

174
Q

indications for intrapartum antibiotics in GBS-unknown

A

PROM
prolonged rupture of membranes (>18 hours)
fever

+/- ssx of chorioamnionitis

175
Q

“failure of germ cell meiosis” describes pathogenesis of

A

teratoma

176
Q

risk factor for endometriosis based on the most likely pathogenesis

A

anterograde outflow obstruction= inc risk of developing endometriosis

177
Q

rotterdam criteria for diagnosis of PCOS

A

*requires 2/3*

  1. oligo-/an-ovulation
  2. hyperandrogenism (measure serum testosterone)
  3. polycystic ovaries
178
Q

HPV 6/11 cause

A

benign warts/condyloma accuminata
respiratory papillomatosis

179
Q

APGAR components

A

@ 1 and 5 minutes
appearance, pulse, grimace, activity, respiration

heart rate (\>100, \<100, 0) 
respiratory effort (reg, irreg, none) 
muscle tone (active, moderate, limp) 
reflex irritability (crying, whimpering, silent) 
color (pink, extremities blue, totally blue) 

> 7= normal
< 6= further evaluation

180
Q

twins separating @ 0-72 hours

A

dichorionic/diamniotic

181
Q

twins separating @ 4-8 days

A

monochorionic/diamniotic
MOST COMMON

182
Q

twins separating @ 8-12 days

A

monochorionic/monoamniotic

183
Q

twins separating @ > 13 days

A

conjoined

184
Q

why are NSAIDs CI in preg

A

risk of premature closure of ductus arteriosus in third tri

185
Q

one indication for all three drugs

indomethacin, nifedipine, mag sulfate

A

tocolysis??

186
Q

where is puberty initiated

A

hypothalamus - GnRH

187
Q

first step in managing 38 WGA with clear fluid leaking from vag, without cervical change

A

confirm that the fluid is amniotic fluid!!

188
Q

biophysical profile

A

fetal tone, fetal movement, fetal breathing, amniotic fluid

189
Q

biophysical profile 4/10 at >/= 32 WGA

A

DELIVERY

190
Q

GBS prophylaxis in - three settings

A
  1. preterm w unknown GBS status
  2. previous infant affected by GBS
  3. GBS bacteriuria anytime during pregnancy
191
Q

percentile at which infants are “large for gestational age”

A

>/= 90th percentile

192
Q

absent grasp reflex

normal biceps and radial reflex

A

klumpke palsy/claw hand deformity (C7-T1)

193
Q

erb duchenne palsy

A

C5-C6

194
Q

brachial plexus injury RF - 8

A
  1. multiparity
  2. LGA infants (>/= 90%ile)
  3. maternal DM
  4. breech presentation
  5. previous child w birth-related brachial plexus injuries
  6. shoulder dystocia
  7. prolonged 2nd stage labor (NOT 1st stage)
  8. vacuum or forceps assisted delivery
195
Q

amsel criteria for diagnosing BV

A
  1. positive whiff test (using KOH)
  2. vaginal pH > 4.5 (lactobacilli normally produce lactic acid, creating acidic enviro around pH 3.8-4.2)
  3. clue cells on saline microscopy
  4. thin, homogenous discharge coating vaginal walls
196
Q

according to comquest, when should mammo screening begin

A

age 50, then q2 years

197
Q

four questions to ask for any OB w contractions

A

contractions

vaginal bleeding

vaginal clear fluid

fetal movement

198
Q

first step in managing previously healthy pt w irreg menses and infertility

A

evaluate for ovulation:

cycle day 21 progesterone

FOLLICULAR –> LH surge –> ovulation (day 14) –> LUTEAL –> inc progesterone (day 21) –> inc basal body temp

199
Q

preg pt w vaginal bleeding + abd/low back pain + firm/tender uterus

DX

RF- 7

COMPLICATIONS- 3

A

placental abruption (separation of placenta from uterus prior to delivery)

RF: abd trauma, cocaine, HTN, polyhydramnios, multiparity, AMA, smoking

inc risk for: maternal hemorrhage, DIC, fetal death

200
Q

placental villi invasion –>

to superficial endometrial decidua basalis

to deeper endometrial decidua basalis

to myometrium

thru uterine serosa +/- bladder

A

NORMAL: to superficial endometrial decidua basalis

PLACENTA ACCRETA: to deeper endometrial decidua basalis

PLACENTA INCRETA: to myometrium

PLACENTA PERCRETA: thru uterine serosa +/- bladder

201
Q

next step in managing a pt measuring at WGA > LMP

and severe N/V

A

TVUS

**b-hCG only to confirm preg**

consider multiple gestation preg!!

202
Q

hCG > 1500 w/out evidence of intrauterine pregnancy

A

ectopic

203
Q

MC delayed complication of D&E

A

delayed= > 72 hours

most common= post-abortal endometritis

*pts given doxycycline before surgery*

204
Q

management of severe preeclampsia

A

immediate induction of labor to reduce risk of maternal death

205
Q

eclampsia inc risk of fetal

A

intrauterine demise – d/t hypoxia

206
Q

important allergies in surgical patients

A

latex (gloves, indwelling catheters)

iodine/betadine (pre-op antimicrobial)

207
Q

STD screening recommendation

A

women < 24 yo who have been sexually active before:

NG/CT and HIV testing annually

208
Q

when should you expect and how should you diagnose Rh alloimmunization in Rh (-) primip with potential Rh (+) baby

6 examples

A

whenever fetal blood may have come into contact with mom’s blood!!

TRAUMA, placenta previa, placental abruption, spontaneous AB, threatened AB, intrauterine procedures

209
Q

non-immune causes of hydrops fetalis - 4

A

lymphatic obstruction

obstructed venous return

hepatocellular dz

fetal infection – parvo B19

210
Q

methods for decreasing vertical HIV transmission

A

C/S when viral load > 1,000

baby: oral zidovudine for 6 weeks (regardless of mom’s viral load)
mom: IV zidovudine (only if vaginal delivery)

211
Q

severe maternal anemia (hbg < 6) is RF for

A

preterm delivery

212
Q

intrauterine adhesions secondary to D&C inc risk of - 3

A

dec flow/amenorrhea

cyclic pelvic pain

infertility (MOST COMMON), recurrent preg loss

213
Q

amenorrhea due to uterine synechiae

A

uterine synechiae= IU adhesions

Asherman’s Syndrome

214
Q

17-hydroxyprogesterone caproate

A

indication: pt w hx of preterm delivery –> reduce risk of preterm delivery in subsequent preg

215
Q

enterocele vs rectocele

A

enterocele= (small bowel) prolapse thru vaginal apex ***common in s/p total hysterectomy

rectocele= prolapse thru posterior vaginal wall

216
Q

darifenacin

tolterodine

oxybutynin

A

anticholinergics, muscarinic antagonists @ bladder

treat urge incontinence

217
Q

CFU when bacteriuria is diagnosed

A

> 100,000

218
Q

why is TMP/SMX contraindicated in preg

A

folic acid antagonist – developmental defects in first tri

219
Q

treatment of choice for fibroids in pt who desires future preg

A

myomectomy

leuprolide may be used to shrink fibroids, but contraindicated in women trying to conceive

continuous GnRH analog –> artificially induced menopause, aka infertility

220
Q

PALM-COEIN for abnormal uterine bleeding

A

polyps

adenomyosis

leiomyoma

malignancy

coagulopathy

ovulatory dysfunction – menarche, perimenopause, endocrinopathies

endometrial

iatrogenic

not yet specified

221
Q

BMI range for:

underweight

normal

overweight

obese

A

BMI

< 18.5 = underweight

18.5-24.9 = normal

25-29.9 = overweight

> 30 = obese

222
Q

pt with ssx mastitis/inflamm cancer

—she is breast feeding

—first step in management??

A

ABX

no need to image

223
Q

screening in pt with fhx ovarian CA

—denies fhx breast CA

A

normal screens!!

CA-125 is not used for screening, only response to therapy

224
Q

torches infections

A

TOXO

OTHER

—varicella

—syphyllis

—parvo

—listeria

RUBELLA

CMV

HSV-2

225
Q

postpartum depression meds- whats the diff

amitryptiline

paroxetine

burpoprion

sertraline

A

amitryptiline= TCA, second-line (refractory depression), CI in suicidal thoughts

paroxetine= SSRI, CI in preg (cardiac malformation)

burpoprion= CI in seizure (dec seizure threshold)

sertraline= SSRI, first line PPD

226
Q

post-meno

hx tamoxifen or pelvic irradiation

rapid uterine growth

uterine mass

—dx?

A

uterine sarcoma

requires surgery + post-op path for definitive dx

227
Q

severe pre-eclampsia management

@ 34-40 WGA

@ >40 WGA

A

@ any WGA, signs of end-organ damage -> DELIVER

@ <40 WGA:

—hydralazine, mag sulfate

—no improvement: VD

@ >40 WGA: vaginal delivery

228
Q

two causes of asymmetric IUGR

A

maternal vascular abnormalities - HTN, DM, smoking, illicit drug use

placental abnormalities

usually abd circumference (low) <<<< head circ (normal)

229
Q

caudal regression syndrome is pathognomonic for

A

**maternal PRE-gestational DM only**

poorly controlled glucose in 2nd/3rd tri= only hyperinsulinemia

230
Q

definitive diagnosis of multiple gestation preg in first tri

A

TVUS - multiple fetal poles (only way to diagnose twins or more)

231
Q

MC nerves trapped in LTCS or other gyn surgery

A

ilioinguinal/iliohypogastric @ lateral edge

232
Q

rx for pt with hot flashes and emotional lability (d/t menopause), w hx of VTE

A

paroxetine (SSRI)

second line —- clonidine (alpha 2 agonist); gabapentin; pregabalin —- venlafaxine (SNRI)

233
Q

contraindications to hormone replacement therapy

A

PMHx of breast cancer, CAD, VTE, endometrial cancer, liver dz

234
Q

38 WGA

no cervical change

fluid leaking from vag

unknown GBS

hx of previous preg complicated by GBS

FIRST STEP?

A

amniotic fluid diagnostic test!!!

premature rupture of membranes diagnosis requires

  1. subjective – hx of fluid leakage
  2. objective/PE – fluid from cervical os/pooling in vag canal
  3. confirmed amniotic fluid - pH (alkaline) or microscopy
235
Q

most significant complication of multiple gestation pregnany

A

preterm delivery

236
Q

35 WGA

N/V, fever, anorexia, abd pain (periumbilical –> RUQ)

U/S shows blind-ended tubular structure extending from R bowel that is no compressible

A

APPENDICITIS

237
Q

when is fetal organogenesis complete

A

around 8 WGA

238
Q

pt presentation sus of endometriosis

sus endometrioma in adnexa

NEXT STEP??

A

LAPAROSCOPY W/ BIOPSY - PATH DIAGNOSIS

239
Q

KLEIHAUER BETKE — WHEN? circumstances?

A

after ABD trauma – tests for placental disruption

240
Q

when is DIRECT COOMBS test relevabt

A

testing for autoimmune hemolytic anemia

— etios —

idiopathic

lymphoproliferative do - CLL, NHL

meds - cephalosporins, levodopa, methyldopa, procainamide

infection - mono, mycoplasma pneumo, HIV

241
Q

ABD trauma to preg pt —- next step in managing??

MOM: O neg, previously anti-Rh-D neg

BABY: unknown blood type

A

INDIRECT COOMBS

testing for maternal anti-Rh-D IgG

U/S can be used later to look for hydrops fetalis when Rh alloimmunization is already known to have occured