Obesity Flashcards

1
Q

8 peptides that INCREASE appetite

A
neuropeptide Y (NPY)
agouti related peptide (AGRP) --> competes w/ aMSH for MSH-4 receptor in hypothalamus
(melanin concentrating hormone (MCH)
Ghrelin
Endocannabinoids
Orexins
Galanins
Opioids)
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2
Q

12 peptides that DECREASE appetite

A
Leptin
Melanocortin (aMSH) --> competes w/ AGRP for MSH-4 receptor in hypothalamus
CRF
Cocaine-amphetamine regulated transcript (CART)
GLP-1
Neuromedin U
Urocortin
CCK (cholycystekinin)
IL-6
CNTF
Peptide YY
Oxyntomodulin
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3
Q

most common bariatric surgery

A

Roux-en-Y 80% - combo restrictive and malabsorptive

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4
Q

MSH-4 receptor in hypothalamus

A

in hypothalamus, controls appetite

  • AGRP increases appetite
  • melanocortin/aMSH decreases appetite
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