Obesity Flashcards
1
Q
8 peptides that INCREASE appetite
A
neuropeptide Y (NPY) agouti related peptide (AGRP) --> competes w/ aMSH for MSH-4 receptor in hypothalamus (melanin concentrating hormone (MCH) Ghrelin Endocannabinoids Orexins Galanins Opioids)
2
Q
12 peptides that DECREASE appetite
A
Leptin Melanocortin (aMSH) --> competes w/ AGRP for MSH-4 receptor in hypothalamus CRF Cocaine-amphetamine regulated transcript (CART) GLP-1 Neuromedin U Urocortin CCK (cholycystekinin) IL-6 CNTF Peptide YY Oxyntomodulin
3
Q
most common bariatric surgery
A
Roux-en-Y 80% - combo restrictive and malabsorptive
4
Q
MSH-4 receptor in hypothalamus
A
in hypothalamus, controls appetite
- AGRP increases appetite
- melanocortin/aMSH decreases appetite