Obesity Flashcards
Upper portion of stomach is stapled to lower part of intestines, leaving only a small gastric pouch
Roux-en-y gastric bypass
80% of stomach is removed, along with a significant portion of small intestine, which leaves behind a small absorptive area
Jejunoileal bypass or biliopancreatic diversion
How much is obesity over ideal body wt?
> 20%
What are 4 different ways to measure body composition?
- Underwater weighing (hydrodensitometry)
- Skinfold
- Bio electrical impedance analysis (BIS)
- Dual-energy x-ray absorptiometry (DEXA)
What is the most commonly used quantified of obesity?
BMI
BMI 25-29.9
Overweight
BMI 30-34.9
Class 1 (low risk)
BMI 35-39.9
Class 2 (moderate risk)
BMI >40
Class 3 (high risk)
How to calculate LBW?
TBW minus fat weight
Which is better, LBW or IDW?
LBW because obese have 20-40% extra lean mass that is not accounted for in IBW
Transdermal and subcutaneous absorption for obesity
Poor subcutaneous fat circulation = decreased subcutaneous absorption
Can a large subcutaneous fat layer interfere with a good intramuscular injection?
Yes
Which drugs show an increased Vd (distribution) in obesity?
Lipophilic drugs
Which drugs show little change in Vd for obesity pts?
Hydrophilic