Obesity Flashcards
Upper portion of stomach is stapled to lower part of intestines, leaving only a small gastric pouch
Roux-en-y gastric bypass
80% of stomach is removed, along with a significant portion of small intestine, which leaves behind a small absorptive area
Jejunoileal bypass or biliopancreatic diversion
How much is obesity over ideal body wt?
> 20%
What are 4 different ways to measure body composition?
- Underwater weighing (hydrodensitometry)
- Skinfold
- Bio electrical impedance analysis (BIS)
- Dual-energy x-ray absorptiometry (DEXA)
What is the most commonly used quantified of obesity?
BMI
BMI 25-29.9
Overweight
BMI 30-34.9
Class 1 (low risk)
BMI 35-39.9
Class 2 (moderate risk)
BMI >40
Class 3 (high risk)
How to calculate LBW?
TBW minus fat weight
Which is better, LBW or IDW?
LBW because obese have 20-40% extra lean mass that is not accounted for in IBW
Transdermal and subcutaneous absorption for obesity
Poor subcutaneous fat circulation = decreased subcutaneous absorption
Can a large subcutaneous fat layer interfere with a good intramuscular injection?
Yes
Which drugs show an increased Vd (distribution) in obesity?
Lipophilic drugs
Which drugs show little change in Vd for obesity pts?
Hydrophilic
Risk of failed block is about 1.5x higher when BMI is greater than what?
30mg/m^2
Obese pts require how much local anesthetics for spinal/epidural anesthesia?
~20% less
Which volatile agent do you NOT use for obesity?
Isoflurane
Sux dose based on what for obesity?
TBW
Vec, cisatracurium, and atracurium are dosed base on what in obesity?
IBW or LBW
Rocuronium is dosed based on what for obesity?
IBW or LBW
What kind of doses are needed for pancuronium in obesity?
Higher
Obese subjects have a what kind of reversal time?
4 fold increase
Sugammadex is dosed based on what for obese?
TBW or IDW plus 40%
Thiopental induction and maintenance is dosed on what for obsesity?
Induction: LBW
Maintenance: TBW
Dexmedetomidine is dosed based on what for obesity?
LBW or IDW
Propofol induction and maintenance is dosed in what for obese?
Induction: LBW
Maintenance: TBW
Etomidate is based on what for obese?
LBW
Fentanyl is dosed based on what for obese?
LBW
Which opioid has the highest lipophilic for obese?
Sufentanil
Remifentanil is dosed based on what?
IBW or LBW
What postop supplementation is used with obese? (6)
- NSAIDs
- Alpha2 receptor agonists
- Ketamine
- Na channel blockers
- Pregabalin
- Nonopioid analgesics
Obesity is an independent risk factor for what?
VTE
Low VTE risk for obese?
LMWH or IPC
High VTE risk for obese?
LMWH and IPC (dosing LMWH higher than normal)
Extend prophylaxis period for obese to how long?
10-15 days