OB Test 2: Infection, Contraception & Infertility Flashcards

0
Q

What are toxoplasmosis, where can you get it and what does it cause?

A

Protazoa, not an STI but can cross the placenta
Found in cat feces and raw meat
Cn cause fetal damage, heart defects, stillborns and abortions

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1
Q

What are TORCH infections?

A
Toxoplasmosis
Other (hepititis) 
Rubella
Cytomegalovirus 
Herpes
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2
Q

What can rubella cause and why don’t we give it to post partum mothers

A

Still born, heart ducts, congenital cataracts

It is a viral vaccine so it can cross the placenta so teach mothers to not get pregnant within 6 months of the vaccine

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3
Q

What does cytomegalovirus cause and how can you prevent it?

A

CMV crosses the placenta and causes disability, hearing loss, hepatosplendmegaly, jaundice

Prevention through really good hand washing

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4
Q

How is herpes spread, what does it mean for birth and how can a newborn get it?

A

Virus from active lesions
Must have a C section
Can get it from amniotic fluid or vaginal birth

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5
Q

What is the transmission of HIV/AIDS?

A

Across the placenta, breastmilk and during labor or birth.

Avoid vaginal births, scalp electrodes and forceps

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6
Q

What are the transmission rates of HIV/AIDS.

A

20% of infants with c-section

1-2% with meds

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7
Q

HIV/AIDS maternal antibodies?

A

Antiviral drugs during pregnancy, don’t breastfeed

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8
Q

What is contraception? What is the difference between birth control and family planning?

A

The intentional prevention of pregnancy during sexual intercourse
Birth control are methods and devices that prevent conception
Family planning is deciding when to conceive

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9
Q

Why are pharmacological contraception methods?

A

Hope

Coitus interruptus: abstinence only good if practiced

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10
Q

Wha are the types of fertility awareness?

A

Rhythm method: relying on avoiding intercourse during fertility cycle. Not too reliable

Symptoms-based methods

  • basal body temperature: ovation temperature
  • cervical mucous: changes at ovulation to thin slippery and clear
  • sympto-thermal: combining signs of temp and mucous
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11
Q

What are barriers to conception?

A

Spermicide

  • foams, cream, film
  • nonoxynol-9 interefere with sperm movement
  • increased HIV transmission
  • timing: important, has to be placed up by cervix before sex
  • failure rate: 29%

Condoms

  • failure rate: 5%
  • barrier against STI

Diaphragm

  • barrier of rubber, cap filled with spermicide anchored by cervix, fitted by physican
  • failure rate 16%
  • kept in 6 hours after

Cervical caps

  • sized and filled with spermicide
  • left in 6 hours after.
  • failure rate 32%
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12
Q

What is the correct condom use?

A
  • pinch top to get air out so semen won’t break condom

- petrollium jelly breaks down the latex

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13
Q

What is toxic shock syndrome?

A

Comes when keep barriers in
Dont use during me station
Only keep things in for 6 hours

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14
Q

What is the action of combined estrogen-progestin contraceptives?

A

GNRH not released so interrupts menstration cycle and interferes with endometrium development

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15
Q

What are the side effects of combined estrogen-progestin contraceptives?

A

Thromboembolism, heart attack, hypertension, if smoker less then 35, stroke

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16
Q

What are the products and failure rates of combined estrogen-progestin contraceptives and what does it interfere with

A

Oral
Transdermal: every day for 3 weeks then out for 1 week
Vagina, ring: removed on fourth week

Failure rate of 8%

Interferes with lactation

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17
Q

What is the action of progesterone only contraception?

A

Inhibits ovulation and thickens cervical mucous

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18
Q

Why is the side effect of progestin-only contraception?

A
Irregular vaginal bleeding 
No menses
Weight gain
Decreased libido
Headaches
Decreased bone density
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19
Q

What are the products and failure rate of progstin-only contraception? Does it interfere with lactation?

A

Oral mini pill: 10% fail rate
Injectable Devo-Provera: one every 3 months, failure rate 3%
Implantable-implanon: thin rod under skin and releases every 3 years

Don’t interfere with lactation

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20
Q

What is emergency contraception action and products?

A

Used within 120 hours of unprotected sex
Action: alters sperm motility and endometrium. Inhibits egg release if prior to ovulation
Products:
-“plan B” is high dose progestin only
- high doses of combined oral contraceptives

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21
Q

Intrauterine device products, years of protection. And insertion?

A

Flare rate <1%
Products:
-paragard: copper T acts as spermicide for 10 year protection
-mirena: progestin, 5 year protection

22
Q

What are the types of sterilization?

A

Tubal ligation
Vasectomy
Reversal: reanastomosis

23
Q

What is tubal ligation?

A

Clamp, cotorize, cut out a piece or apply bands
Goal is to occlude tubes, done easily in c-section or laporodomy
Fill abdomen with gas and after may have shoulder pain so give analgesic

24
What is a vasectomy?
Out patient procedure with local anesthetic Have to do sperm count twice Sperm absorbed in the body Failure rate is 0.15%
25
How do you reverse sterilization?
Stitch tubes back together | Increase risk of ectopic pregnancy
26
What is infertility? Primary and secondary?
The inability to conceive after 1 year of unprotected sexual intercourse Primary: never been pregnant Secondary: pregnant once and not again, can't carry fetus to term
27
What are the psychosocial effects of infertility?
Major life stressor Attitude of health care provider Religious considerations Cultural considerations
28
What are requirements for pregnancy?
``` Ovulation Sexual intercourse Sperm placed near cervix Viable oocyte and sperm Prepared endometrium ``` Average sex from 2-3 times a week
29
What are associated factors to pregnancy?
Abnormal reproductive system development Abnormal hormonal control Blockage: scarring
30
How do you assess ovulation and a hormone analysis?
Assessment of ovulation: basal body temperature, cervical mucous change Hormone analysis: endometrial biopsy
31
How do you do tubal patency assessment?
Hysterosalpingograohy | Laparoscopy
32
What is hysterosalpingography?
Inject opaque dye to see if tubes are open Is there a problem with sperm getting to the egg May cause referred shoulder pain
33
What is laparoscopy?
Abdomen inflated with CO2 Post-procedural pain Can see endometriosis
34
What are female factors to fertility?
Congenital abnormalities - DES exposure - bicornuate uterus Ovarian - hormonal balance: amennorreic, dysmenorrhea indicated ovulation
35
Medication for infertility?
Ovulation stimulants - Clomid: increase FSH and LH - repronex: pro lactation secretion - parlodel: interferes with prolactin. Hormone replacement therapy - GnRH and Progrsterone Antibiotics
36
What are tubal factors?
Inflammation and infection: biggest cause blockage in Fallopian tubes Endometriosis Treatment: Prevention, electrocotory Prevention
37
What are uterine factors?
``` Congenital defects Adhesions and scarring Tumors, fibrosis, polyps Assessment Treatment ``` Scar prevents implantation
38
Vaginal & cervical factors?
Ph < 4 in vagina Ph > 7 at cervix Cervical competence fall open Isoimmunization: immunized to self Trichinosis increases acidity Stress, antibiotics and diabete changes bodies pH
39
What is treatment?
Prevention Good hygiene: maintain vaginal and cervical pH Treat chronic cervicitis: freeze abnormal tissue, burn it away Artificial insemination Desensitization
40
What is male infertility?
Sperm must be normal, motile, adequate in number and placed near cervix
41
What is male infertility congenital defects?
Hypospadius: surgical correction
42
What is male infertility and substance use?
Alter morphology and amount of sperm
43
What is male infertility related to blockage?
Infections
44
What are male infertility hormones?
Hypothalamus Pituitary Testicular Adrenal
45
With male infertility how do you do semun analysis?
2-3 times | 2-5 mL of ejaculate, 50% active
46
Wha is the post coital test
After intercourse women vaginal contents are examined to see if tbe are penetrated
47
What is the treatment of male infertility?
Prevvention and treatment of STI | surgical repair and lifestyle changes
48
What are the reproductive alternatives?
``` IVF GIFT Micro manipulation Therapeutic insemination Surrogates Adoption ```
49
What is IVF?
In vitriol fertilization - ovulation is stimulated - graafian follicle are aspirated and placed in tissue culture and mised with sperm - progesterone injections to prepare endometrium - blastocyst transferred to uterus to implant
50
What is GIFT?
Gamete intrafallopian tube transfer Ovum and sperm placed in Fallopian tube to combine. Not outside body
51
What is micromanipulation?
Intra cytoplasmic soerm injection | ICSI
52
What is therapeutic insemination?
Husband or donor inseminated woman