OB Notes (Jay) Flashcards
What is the classic triad in assessing amniotic fluid embolism?
- Acute hypoxemia
- Severe hypotension
- Coagulopathy
Other symptoms:
- Pulmonary edema
- Cyanosis
- CV arrest
- DIC
- Fetal distress
- Seizures
What does amniotic fluid contain? (3)
- Prostaglandins
- Leukotrienes
- Fetal debris
What is the treatment for parturient suffering amniotic fluid embolism? (3)
- Supportive with aggressive cardiopulmonary resuscitation
- CPR (not effective before delivery of fetus)
- Immediate cesarean
What is the critical period of organogenesis?
2-8 weeks
When should elective surgeries be deferred until?
Should be deferred until after delivery
If surgery is necessary wait until 2nd or 3rd trimester.
What drugs are OK during the first trimester? (3)
- Tylenol
- Benadryl
- Phenergan
What is cerclage?
It is the reinforcement of the cervix to prevent premature cervical dilation in a patient with an incompetent cervix.
Painless dilation of the cervix occurs in the midtrimester of preggnancy. The membranes bulge through the cervix and rupture, followed by delivery of severely premature infant.
What is the spinal level blockade goal in a regional block in a cerclage?
T8–belly button
When may an LMA be safely used for a cerclage?
<15-18 weeks
Greater than 18 weeks, an ETT with RSI must be used.
What is a category A drug defined as?
Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters.)
What is a category B drug defined as?
Animal reproduction studies have failed to demonstrate risk to the fetus and there are no adequate and well-controlled human studies in pregnant women
What is a category C drug defined as?
Animal reproduction studies HAVE sown an adverse effect on the fetus and there are no adequate studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
What is a category D drug defined as?
**There is positive evidence of human fetal risk. **
Potential benefits may warrant use of the drug in pregnant women despite potential risks.
What is a category X drug defined as?
Studies in humans or animals HAVE demonstrated fetal abnormailities and there is positive evidence of human fetal risk based on adverse reaction data.
Risks involved in use of the drug in pregnant women CLEARLY outweigh potential benefits.
What drugs start with an “A” and should be avoided during the first trimester of pregnancy? (5)
ACE inhibitors
Alcohol
Androgens
Anti-thyroid drugs
Aspirin