OB MTB Flashcards
embryo is considered fetus at how many weeks gestation?
how long infant for?
8 weeks
infant for 1 year after birthNagele rule
Nagele rule
EDD : LMP - 3 months + 7 days
gestational age?
trimester breakdown
number of days since LMP
1st: 0-12 weeks (14 gestational age)
2nd: 12-24 weeks
3rd: 24-delivery
screening based on trimesters
1st: FHTs with Doppler
2nd: triple/quad screen, movement at 16-20 wks, u/s at 18-20 wks GA
3rd: frequent visits, monitor labs
Gs and Ps of female who presents with her 6th pregnancy, has had 2 abortions, 2 children born at term, and set of twins born preterm
G6P2124
G TPAL
(twins born preterm count as 1 pregnancy)
one of first signs of pregnancy on PE
Goodell sign: softening of cervix, may be felt at 4 weeks
in contrast, quickening is first time mother feels fetal movement
other signs of pregnancy
Ladin:
Chadwick:
chloasma:
Ladin: softening of midline uterus (6 wks)
Chadwick: blue discoloration of vagin and cervix (6-8 wks)
chloasma: “mask of pregnancy” (16 wks)
how rapidly is B-hCG produced in 1st trimester?
when does it peak?
doubles every 48 hrs in 1st 4 wks
peaks at 10 wks
drop in 2nd trimester, and rise slowly again in 3rd trimester to levels of 20-30,000 IU/mL
when/what B-hCG level should a gestational sac be seen on ultrasound?
at 5 wks or B-hCG of 1000-1500 IU/mL
changes in CO, HR, BP
^CO, ^HR, decreased BP (lowest 24-28 wks)
changes in coagulation
hypercoagulable, ^fibrinogen
but no increase in PT, PTT, INR
1st trimester tests
see every 4-6 wks
11-14 wks: u/s for GA and nuchal translucency
blood tests, pap smear, Gc/Clamydia
1st trimester screening for chrom. abn.
most accurate test to establish gestational age in 1st trimester
U/S, esp. 11-14 wks
2nd trimester screening
triple/quad screen 15-20 wks
ultrasound 18-20 wks for fetal malformations
3rd trimester visits
q2-3 wks until wk 36 then qwk
27: CBC (iron if hgb less than 11)
24-28: glucose load (140+ 3 hr gtt)
36: cerv. cx for Gc/Chl, recvag cx for GBS
when to get CVS
amniocentesis
CVS: 10-13 wks in AMA or known genetic disease
amniocentesis: 11-14 wks
most common site of ectopic
risk factors?
ampulla of fallopian tube
PID, IUD, previous ectopic
ectopic pregnancy:
presentation and tests
u/l low abdominal or pelvic pain, vaginal bleeding, hypotensive with peritoneal signs if ruptured
tests: B-hCG, U/S, laparoscopy (tx)
unstable ruptured ectopic pts
need IV fluids, +/- blood products, +/- dopamine to stabilize BEFORE surgery
stable ruptured can go straight to sx
medical tx of non-ruptured ectopic
MTX labs: B-hCG, CBC, t/s, LFTs look for 15% drop in hCG in 4-7 days if not, 2nd dose MTX if still not decreasing, resort to surgery
exclusion criteria for MTX
immunodeficiency, noncompliant, hepatotoxicity, 3.5cm+, FH beat auscultated (^risk failure)
ectopic surgical tx
salpingostomy (cutting hole in tube, preserves)
salpingectomy (remove whole tube)
give RhoGAM if Rh negative
etiologies of abortion
*chromosomal abnormalities
anatomic abnormalities, infection (STDs), immune (aPL syndrome), endocrine (HTN, DM), malnutrition, trauma, Rh isoimmunization
tests to do in abortion
CBC, type/screen, U/S