OB MTB Flashcards
embryo is considered fetus at how many weeks gestation?
how long infant for?
8 weeks
infant for 1 year after birthNagele rule
Nagele rule
EDD : LMP - 3 months + 7 days
gestational age?
trimester breakdown
number of days since LMP
1st: 0-12 weeks (14 gestational age)
2nd: 12-24 weeks
3rd: 24-delivery
screening based on trimesters
1st: FHTs with Doppler
2nd: triple/quad screen, movement at 16-20 wks, u/s at 18-20 wks GA
3rd: frequent visits, monitor labs
Gs and Ps of female who presents with her 6th pregnancy, has had 2 abortions, 2 children born at term, and set of twins born preterm
G6P2124
G TPAL
(twins born preterm count as 1 pregnancy)
one of first signs of pregnancy on PE
Goodell sign: softening of cervix, may be felt at 4 weeks
in contrast, quickening is first time mother feels fetal movement
other signs of pregnancy
Ladin:
Chadwick:
chloasma:
Ladin: softening of midline uterus (6 wks)
Chadwick: blue discoloration of vagin and cervix (6-8 wks)
chloasma: “mask of pregnancy” (16 wks)
how rapidly is B-hCG produced in 1st trimester?
when does it peak?
doubles every 48 hrs in 1st 4 wks
peaks at 10 wks
drop in 2nd trimester, and rise slowly again in 3rd trimester to levels of 20-30,000 IU/mL
when/what B-hCG level should a gestational sac be seen on ultrasound?
at 5 wks or B-hCG of 1000-1500 IU/mL
changes in CO, HR, BP
^CO, ^HR, decreased BP (lowest 24-28 wks)
changes in coagulation
hypercoagulable, ^fibrinogen
but no increase in PT, PTT, INR
1st trimester tests
see every 4-6 wks
11-14 wks: u/s for GA and nuchal translucency
blood tests, pap smear, Gc/Clamydia
1st trimester screening for chrom. abn.
most accurate test to establish gestational age in 1st trimester
U/S, esp. 11-14 wks
2nd trimester screening
triple/quad screen 15-20 wks
ultrasound 18-20 wks for fetal malformations
3rd trimester visits
q2-3 wks until wk 36 then qwk
27: CBC (iron if hgb less than 11)
24-28: glucose load (140+ 3 hr gtt)
36: cerv. cx for Gc/Chl, recvag cx for GBS
when to get CVS
amniocentesis
CVS: 10-13 wks in AMA or known genetic disease
amniocentesis: 11-14 wks
most common site of ectopic
risk factors?
ampulla of fallopian tube
PID, IUD, previous ectopic
ectopic pregnancy:
presentation and tests
u/l low abdominal or pelvic pain, vaginal bleeding, hypotensive with peritoneal signs if ruptured
tests: B-hCG, U/S, laparoscopy (tx)
unstable ruptured ectopic pts
need IV fluids, +/- blood products, +/- dopamine to stabilize BEFORE surgery
stable ruptured can go straight to sx
medical tx of non-ruptured ectopic
MTX labs: B-hCG, CBC, t/s, LFTs look for 15% drop in hCG in 4-7 days if not, 2nd dose MTX if still not decreasing, resort to surgery
exclusion criteria for MTX
immunodeficiency, noncompliant, hepatotoxicity, 3.5cm+, FH beat auscultated (^risk failure)
ectopic surgical tx
salpingostomy (cutting hole in tube, preserves)
salpingectomy (remove whole tube)
give RhoGAM if Rh negative
etiologies of abortion
*chromosomal abnormalities
anatomic abnormalities, infection (STDs), immune (aPL syndrome), endocrine (HTN, DM), malnutrition, trauma, Rh isoimmunization
tests to do in abortion
CBC, type/screen, U/S
if no products of conception found on u/s ?
if some POCs found ?
if intact POCs but bleeding and cervix dilated?
if intact POCs, no cervical dilation but bleeding?
if intact POCs but fetal death?
infection of uterus/surrounding areas?
complete abortion (f/u)
some: incomplete (D&C/medical)
bleeding/dilated: inevitable (D&C/medical)
bleeding/no dilation: threatened (bed/pelvic rest)
fetal death: missed (D&C/medical)
infection: septic abortion (D&C and IV abx (levaquin, metronidazole)
medical treatment of abortions (incomplete, inevitable, missed)
misoprostol (PGE1 analog): help open cervix and expulse fetus
if Rh- give RhoGAM
complications of multiple gestations
spontaneous abortion of 1 fetus, premature L+D, placenta previa, anemia
preterm contractions with cervical dilations called ?
preterm labor
if “gush of fluids” consider PROM
if just preterm contractions will not lead to cervical change
risk factors for preterm labor
PROM, multiple gestations, previous hx of preterm labor, placental abruption, maternal factors (anatomy, infection, pre-E, intra-abd. sx)
when NOT to stop preterm labor
pre-E/eclampsia, cardiac disease, cervical dilation of +4cm, maternal hemorrhage (placental abruption, DIC), fetal death, chorioamnionitis, between 34-37 wks, greater than 2500g