Ob/Gyn Flashcards
What type of effects does Tobacco and Cocaine have on neonates when taken during pregnancy?
- Tobacco–> low birth wt
- Cocaine –> low birth wt 2/2 vasoconstrictive placental insufficiency
Name Intrauterine Maternal factors that inhibit fetal growth? - 5
Includes Alcohol use
Always consider Gestational Dating may be inaccurate
Name Intrauterine Placental abnormalities that inhibit fetal growth? - 3
Always consider Gestational Dating may be inaccurate
Name Intrauterine Fetal abnormalities that inhibit fetal growth? - 4
Always consider Gestational Dating may be inaccurate
What office tool (other than LMP) is used to estiamate gestational age?
Fundal height (palpate superior aspect of enlarged uterus)
Name Factors that ⬆︎ Risk for Vertical transmission of HIV -6
- Unprotected Sex during pregnancy (chorioamnionitis and other STI ⬆︎HIV transmission)
- Advanced Maternal HIV viral load
- Membrane rupture > 4 hrs prior to delivery in Mother not on HAART
- Vaginal Delivery
- Breastfeeding
- Premature Delivery before 37 wks
You’ve just discovered a positive rapid HIV test on pregnant pt in labor
Name Factors that ⬇︎ Risk for Vertical transmission of HIV -3
- HAART if viral load > 1000 copies
- C-section prior to onset of labor and rupture of membranes
- NO Breastfeeding
What is the Ballard Tool?
Uses Physical and Neuromuscular signs to estimate gestational age
What constitutes a FULL term infant?
≥ 37 wks gestation
What clinical problems are associated with SGA (Small for Gestational Age)?-3 …and why?
- hypOglycemia (⬇︎ glycogen stores and gluconeogenesis)
- hypOthermia (⬆︎Surface area and ⬇︎SubQ insulation)
- Polycythemia presenting w/Respiratory distress (Chronic hypoxia)
What are the major risk factors for Breast CA - 6
- 1st degree relative with breast CA
- Excess estrogen (menstruating outside of 12-45 y/o range vs utero DES vs HRT)
- Genetics (BRCA 1/2 mutation)
- Alcoholic
- Obesity
- Therapeutic radiation
Average Menopause onset = 51
Guidelines for PAP Smear Cervical CA Screening - 3
- [Age 21 - 65 every 3 years (cytology only)] ≥ 3x
- [Age 30-65 can alternatively get Co-HPV Testing every 5 years] ≥ 2x
- Risk Groups (immunocompro/CIN2 or 3 hx/CA/utero DES pts/smoking) need more frequent screening
Guidelines for Breast CA screening - 3
- 45-54 get mammograms every year
- > 55 cont mammograms every year OR switch to every 2 years
- 40-44 have the option
No mamm in pt < 40 unless known BRCA mutation
What are characteristics of a breast lump that suggest malignancy - 5
- single
- solid (consider US to differentiate from cystic lesion)
- immobile
- >2 cm
- irregular borders
Pregnancy and Breast stimulation are normal causes of nipple discharge
What are pathologic causes? - 5
- CA (Intraductal/Paget’s/DCIS/Mammary duct ectasia)
- Hormone imbalance
- Trauma
- Abscess
- Meds (Antidepressant/Antipsychotics/AntiHTN)
Risk factors for Cervical SQC - 5
- Early Sexual Intercourse
- Large # of lifetime sex partners
- utero DES
- Smoking
- Immunocompro
Dx for Menopause
No menstruation for 1 year straight!
Average Menopause onset = 51
S/S of Menopause - 4
- Menstrual irregularity in older female (heavy/last>1 week) = perimenopause
- Hot Flashes (last 30 sec - 10 min)
- Atrophic vaginitis –> Vaginal Dryness, dyspareunia, urinary sx, smooth vaginal mucosa
- Mood Swings
What are risk factors for Osteoporosis? - 9
Bone Mineral Density (T-score) ≥ 2.5 SD BELOW mean
- ⬇︎Estrogen
- LOW BMI (malnutrition/malabsorption)
- Sedentary lifestyle
- Poor Ca+ intake (body needs 1000mg premenopausal and 1200mg post)
- Family or personal hx of osteoporotic fracture
- Smoking
- EtOH abuse
- White race
- Steroids
Preventitive measures for Osteoporosis? - 4
Bone Mineral Density ≥ 2.5 SD below mean
- Dietary Ca+ intake 1200-2500 mg/day
- Dietary VitD intake 600 IU/day
- Sun > 10 min/day
- Weight bearing exercises (walking,jogging,dancing)
Only use supplements WHEN ABSOLUTELY NEEDED
Guidelines for Osteoporosis screening - 2
Bone Mineral Density (T-score) ≥ 2.5 SD BELOW mean
- Women ≥65 = DEXA
- Women < 65 get DEXA if fracture risk is ≥ a 65 yo WHITE woman per FRAX score
Bone Mineral Density (T-score) ≥ 2.5 SD BELOW mean
Guideliness for Chlamydia Screening (Women vs Men)-3
Women
- ALL sexually active women < 25
- Sexually active women > 25 if high risk
Men: Insufficient evidence :-(
What are the major s/s of Pregnancy - 7
- Amenorrhea (this may be normal in teens)
- NV
- Breast TTP
- Urinary frequency
- [Hegar’s Uteral / Goodell’s Cervical Softening]
- Uteral Enlargement
Remember to screen sex active women < 25 for Chlamydia
Abortion is legal up to ____ weeks gestation ; How do you calculate Estimated Gestational age (EGA) - 2 options?
22 weeks ; [Current Date - date of LNMP] = EGA
OR
serial testing of SERUM βhCG
( LNMP = last normal mentrual period)
Abortion is legal up to ____ weeks gestation ; How do you calculate Estimated Due Date (EDD) - 3?
22 weeks ; [date of LNMP] + 1 year - 3 months + 1 week = EDD
- THIS IS KNOWN AS NAEGELE’S RULE and is [+/- 2 wk accuracy]*
- Use US to confirm BUT ONLY IN WOMEN < 20 WKS GESTATION*
Which labs do you order initially for newly discovered Prenatal? - 6
- CBC (detect anemias)
- Blood Type & Screen (RH-D = RH neg, and these women need anti-D Ig)
- Rubella IgG
- Hep B surface antigen
- RPR
- HIV
What’s the best way to diagnose ectopic pregnancy or miscarriage? - 2
- SERUM βhCG level trend
- Progesterone ( ectopic/miscarriage < 5 - 25 < healthy pregnancy) - not reliable tho
How much and When is [RhoGam Anti-RhD Ig] administered to pregnant women? - 4
- 50mcg sometime during [< 14 WG: 1st trimester]
- 300mcg at 28 WG
- unspecificied dose within 72 hrs after delivery
- unspecificed dose with any episode of vaginal bleeding
WG = Weeks Gestation
Lab w/u for [1st trimester vaginal bleeding]
Remember: this is 25-50% chance of miscarriage
- Serum βhCG trend WITH Pelvic US
- CBC
- Wet Mount for trichomonas
- GC/Chlamydia PCR
- Progesterone ( ectopic/miscarriage < 5 - 25 < healthy pregnancy) - not reliable tho
βhCG levels have to be ____ for pregnancy to be detected via transvaginal US, and usually _____ when transabdominal US can finally detect it
What are βhCG levels during:
A: Ectopic Preg/Miscarriage
B: Molar Pregnancy
βhCG levels have to be 1500-1800 for conclusive pregnancy detection via transvaginal US and usually >5000 when transabdominal US can finally detect it
A: Ectopic Preg/Miscarriage = low βhCG
B: Molar Pregnancy = > 100,000 βhCG!!!
βhCG should double every 2 days in normal pregnancy for first 7 weeks
Why are serial βhCG more important than point value βhCG?
[βhCG should double every 2 days x first 7 weeks] in normal pregnancy so tracking the velocity trend is important
What are the options for Mngmt of Miscarriage - 3
- Expectant: Watch waiting for products of conception to expel naturally in 2-6 weeks
- Surgical: Dilitation & Curettage (D&C) - cant be done during infection
- Medical: 800mcg Vaginal Misoprostol - takes up to 2 weeks for expel
ALL REQUIRE 1 WEEK FOLLOW UP
Why is the TDaP given to ____ week gestation pregnant patients?
27-36 week ; Protects BABY from Pertussis
1st trimester is ___ weeks gestation
What are the 3 biggest questions to ask during history taking for these patients? Why?
< 14 weeks
- NV? - asking because this is treatable
- Vaginal Bleeding?
- Cramping?
2nd trimester is ___ weeks gestation
What are the 5 biggest questions to ask during history taking for these patients? Why?
14 - 27 weeks
- Leakage of Fluid? -OOP
- Vaginal Bleeding? -OOP
- Cramping/contraactions? -OOP
- Fetal Movement? -OOP
- Anticipatory Guidance [Breastfeeding/Car seats/OCP]
It is a medical emergency when Fetal Movement is not felt by 24 wks!
2nd trimester is ___ weeks gestation
Fetal Movement should be felt when? ; It is a medical emergency when Fetal Movement is not felt by ____
14 - 27 weeks
It is a medical emergency when Fetal Movement is not felt by 24 wks!
3rd trimester is ___ weeks gestation
What are the 5 biggest questions to ask during history?
28 - 42 weeks
- Leakage of Fluid?
- Vaginal Bleeding?
- Cramping/Contractions?
- Fetal mvmnt?
- S/S Preeclampsia (HTN/edema/Proteinuria)