OB Final Flashcards
question
answer
24 weeks pregnant woman with multifetal pregnancy manifested for signs of preterm labor. What is the treatment for the case?
A) Corticosteroids
B) Bed rest
C) Tocolytics
D) Pessary
C) Tocolytics
Effects on pregnant patient of infection
A) Serologic
B) Gestational Age
C) Mode of Acquisition
D) Immunologic
B) Gestational Age
AOTA?
Intrauterine fetal transfusion is management option for infection caused by:
A) Parvovirus
B) CMV
C) Influenza
D) Mumps
A) Parvovirus
Most common anomaly in congenital rubella syndrome seen in 60-75%
Sensorineural deafness
The most common anomaly associated with congenital hyperplasia in 60-75%?
A) Malformation
B) Cardiac Anomaly
C) Mental retardation
B) Cardiac Anomaly
In contrast to congenital varicella, varicella-zoster immune globulin should be administered in neonatal varicella
A) 2 days before and a week after delivery
B) 7 days before and 7 days after delivery
C) 5 days before and 5 days after delivery
D) 5 days before and 2 days after delivery
D) 5 days before and 2 days after delivery
Diagnosis of toxoplasmosis in the mother is best confirmed by serology. Serologic test suggestive of an acute infection includes the identification of
A) IgM antibody B) Extensive high IgG Ab titer C) IgG seroconversion from negative to positive D) A and B E) A, B, C
E) A, B, C
The most valuable test for congenital toxoplasmosis is by detection through PCR. What specimen is obtained?
A) Maternal blood
B) Maternal tissue
C) Amniotic fluid
D) Fetal tissue
C) Amniotic fluid
Confirmatory test for VZV
A) Antibody VZV IgM
B) Antibody VZV IgG
C) VZV IgM
D) VZV IgG
C) VZV IgM
As opposed to congenital rubella, neonatal rubella happens when?
Congenital rubella – happens during pregnancy
Neonatal rubella – acquired after birth
True about influenza vaccine?
A) All health worker should be vaccinated yearly
B) 70-90% efficacy and decrease the severity
C) All women planning to be pregnant should be vaccinated in flu season
D) A and C
E) All of the above
E) All of the above
True on Influenza immunization
A) Getting pregnant at flu season
B) 70-90% efficacy and reduced severity
C) Healthworkers require immunization
D) All of the above
D) All of the above
) In congenital toxoplasmosis infection, 40% neonates born to mothers with evidence of disease, most likely to occur when maternal infection develops during
A) 1st trimester
B) 2nd trimester
C) 3rd trimester
D) After delivery
C) 3rd trimester
40% of neonates affected with toxoplasmosis infection given that the mother during pregnancy has the said disease
A) Maternal blood
B) Fetal blood
C) Amniotic fluid
A) Maternal blood
Rubella crosses the placenta thru hematogenous dissemination, rate decreases with increasing gestational age. However, 50-80% develop infection as early as this gestation
A) 12 weeks
B) 14 weeks
C) 18 weeks
D) 20 weeks
B) 14 weeks
The initial immune response of the fetus after delivery came from?
A) Cell-mediated immunity
B) Humoral
C) Both
D) Neither
C) Both
What is the proper way of collection for screening of group B streptococcus?
A) From distal vagina and anorectal B) Use speculum for proper visualization of vagina and rectum C) Proximal vagina and anorectal D) A and B E) A and C
D) A and B
Not true about Antileukotrienes effective in the management of acute asthma
Effective in the management of acute asthma
Prophylacyive antibiotic
A) Group A streptococcus
B) Group B streptococcus
C) Streptococcus agalactiae (GBS)
D) All of the above
D) All of the above
Classic sign of Sick Neonate, Except:
A) Poor suck
B) Vomiting
C) Lethargy
D) Hyperthermia
D) Hyperthermia
response to sepsis may be hypothermia
Most common cause of Neonatal sepsis
A) Group A streptoccocus
B) Listeria monocytogenes
C) Streptococcus agalactiae
D) Mycobacterium leprae
C) Streptococcus agalactiae
Acquired neonatal infection
A) 24 hours
B) 48 hours
C) 72 hours
D) 96 hours
C) 72 hours
Sulfadoxine-pyrethamine is given to:
A) Toxoplasmosis
B) Malaria
C) Hansen’s Disease
D) Listeriosis
A) Toxoplasmosis
In pregnancy, the predominant CD4 T-cell is/are?
A) Th1
B) Th2
C) Th3
D) Th4
B) Th2
The primary fetal response in case of exposure to infectious agents is?
A) IgG
B) IgA
C) IgM
D) IgE
C) IgM
Entry of vertical transmission during pregnancy includes?
A) Placenta
B) Labor and Delivery
C) Breast Feeding
D) All of the Above
D) All of the Above
Not associate with fetal effects?
A) Mumps
B) Varicella Zoster
C) Measles
D)German measles
A) Mumps
After being given a mumps vaccine, it is recommended that women should not get pregnant for the next?
A) 2 weeks
B) 4 weeks
C) 6 weeks
D) 8 weeks
B) 4 weeks
Associated with placental trophoblast invasion?
A) Group A streptococcus
B) Group B streptococcus
C) Salmonellosis
D) Listeria Monocytogenes
D) Listeria Monocytogenes
Development of CMI and humoral immune response occurs by?
a. 5-10 weeks
b. 8-15 weeks
c. 15-20 weeks
d. 21-25 weeks
b. 8-15 weeks
question
answer
Best measures for assessment of asthma include the following:
A. Subjective assessment B. FEV and PEFR C. Arterial blood gas analysis D. Clinical assessment E. Aota
B. FEV and PEFR
Guidelines to management of labor and delivery in asthmatic
mother/woman includes the ff except:
ANS: PFA 2 AND ERGONOVINE for uterine atony.
Which of the following is the Most common cause of Pneumonia?
A. Mycoplasma pneumonia
B. Legionella Pneumonia
C. Influenza A
D. CA MRSA
C. Influenza A
The ff. describes the diagnostic procedures used for Pneumonia:
A. Chest xray accurately predicts the etiology
B. Chest radiography is essential for the diagnosis
C. Sputum cultures is primarily indicated in all cases of pneumonia
D. All of the above
B. Chest radiography is essential for the diagnosis
A 30 year old G3P2 on her 30 week AOG with history of mild upper respiratory tract infection, present with cough, dyspnea
and fever. What is the effective initial monotherapy recommended:
A. Levofloxacin
B. Vancomycin
C. Erythromycin
D. Linezolid
C. Erythromycin
Exceptions to delay INH tx to pregnant tuberculin positive women.
A. Known skin test converter B. Positive PPD exposed to active dse. C. HIV women D. A and C E. AOTA
E. AOTA
Beta-agonist given to asthmatics in order to
abate bronchospasm
Severe asthma type not responding to 30-60 minutes intensive therapy
Status Asthmaticus
Positive for Tuberculin Skin Test (TST)/Purified Protein Derivative (PPD)
greater > 5mm wheal formation/induration after 48-72 hours
Continued treatment for TB
a. Isoniazid and Rifampicin
b. Ethambutol and Rifampicin
c. Ethambutol and Pyrazinamide
a. Isoniazid and Rifampicin
Carbon monoxide, later in pregnancy
a. Structural anomalies
b. Growth restriction
c. Anoxic encephalopathy
d. No fetal effects
c. Anoxic encephalopathy
With no known risk factors for TB, aninduration or wheal of this size is indicative of a need for Anti-TB treatment:
a. > 3mm
b. > 5mm
c. > 10mm
d. > 15mm
d. > 15mm
Breastfeeding is NOT a contraindication during Anti-TB treatment
a. True
b. False
a. True
question
answer
Cardiac output increases by approximately what percent?
Cardiac output increases approximately 40%
Increase in CO is due to
Stroke Volume
When is CO maximal?
28 weeks AOG
Normal (left/right) ventricular function is maintained during pregnancy
Normal left ventricular function is maintained during pregnancy
5 Symptoms of heart disease during pregnancy
. Progressive dyspnea or orthopnea . Nocturnal cough . Hemoptysis . Syncope . Chest pain
diagnostic studies for heart disease
electrocardiography, cxr, echocardiography
15° left axis deviation in ecg due to
due to an elevated diaphragm in
pregnancy
what are findings in heart disease in pregnancy
. 15° left axis deviation – due to an elevated diaphragm in pregnancy . Mild ST changes . Reduced PR interval . Inverted or flattened T waves . 1 wave in lead D1
Which permits accurate diagnosis of most heart diseases during
pregnancy?
electrocardiography, cxr, echocardiography
echocardiography
slight limitation of physical activity
Class I
Class II
Class III
Class IV
Class II
comfortable at rest
Class I
Class II
Class III
Class IV
Class I, II, and III
ordinary physical activity is undertaken, discomfort in the form of excessive fatigue, palpitation,dyspnea, or anginal pain results
Class I
Class II
Class III
Class IV
Class II
marked limitation of physical activity
Class I
Class II
Class III
Class IV
Class III
less than ordinary activity causes excessive fatigue, palpitation, dyspnea, or anginal pain
Class I
Class II
Class III
Class IV
Class III
Which NYHA class is a predictor of cardiac complications?
Class III and IV
What singular clinical finding is a predictor of cardiac complication?
cyanosis
(Left/Right) sided heart obstruction is a predictor of cardiac complication
Left sided heart obstruction
Define left sided heart obstruction
. Mitral valve area of
. Aortic valve are
. peak left ventricular outflow tract gradient
. Ejection fraction
. Mitral valve area of <2 cm2
. Aortic valve are below 1.5 cm2
. peak left ventricular outflow tract gradient >30mmHg by 2D Echo
. Ejection fraction <40%
risk of congenital heart disease in offspring is?
risk of congenital heart disease in offspring is 3-4%
What cardiovascular changes in pregnancy occur that affect general management?
. Blood volume
. CO
. decline in systemic vascular resistance
. hypercoagulability
Basilar rales, Dyspnea on exertion, Excessive coughing, Hemoptysis, Progressive edema, Tachycardia
Are clinical symptoms of which NYHA Class?
Class I and II
What is the specific danger in illicit drug use on cardiac pathology?
raises the risk of infective endocarditis
Which anesthetic is preferred with CVD?
epidural
in CVD what is the preferred position during labor?
Semirecumbent position with lateral tilt
Findings suggestive of impending ventricular failure during labor
Heart rate
RR
Associated with
Heart rate of > 100 beats/min
RR >24/min
Associated with dyspnea
Manifestation of Intrapartum Heart Failure (2)
Pulmonary edema with hypoxia, Hypotension
Pros and cons of porcine tissue valves
Pro: Safer for pregnancy, Anticoagulant not required
Con: Needs another replacement in 10 to 15 years
What is management when there is mechanical valve replacement?
. Full coagulation throughout pregnancy
. Use unfractionated heparin between 6-12 weeks and at 36 weeks
. Starting at 35,000 U SQ, BID
. Warfarin is used for the rest of the pregnancy
. If delivery occurs before effect of anticoagulant fades, may give Protamine sulfate thru IV
Which type of contraception is contraindicated?
combination OCP
most common cause of mitral stenosis lesions
Rheumatic endocarditis
management of mitral stenosis
Physical activity limited Reduce salt intake Diuretic started B-blockers IV verapamil/electrocardioversion Digoxin Heparin
Mitral insufficiency is (well/poorly) tolerated during pregnancy. Prophylaxis against what is indicated?
Well tolerated during pregnancy
Prophylaxis against bacterial endocarditis indicated
What Implies myxomatous degeneration?
mitral valve prolapse
mitral valve prolapse involves
Valve leaflets, Annulus, Chordae tendinae
Normal aortic valve area vs Severe stenosis.
What is the pressure gradient in aortic stenosis?
Normal aortic valve area: 3-4 cm2
Severe stenosis: <1 cm2
Pressure gradient: <5mmHg
Management of aortic stenosis?
Limitation of activity
Treat for infection
Valve replacement
Valvotomy
Aortic insufficiency is (well/poorly) tolerated during pregnancy.
Well tolerated during pregnancy
Pt has Systolic ejection murmur, pulmonary area louder during
inspiration. What is Dx?
pulmonic stenosis
2nd most common congenital heart lesion in adults
atrical septal defect
When is ventricular septal defects well tolerated?
well tolerated for small to moderate, left to right shunts
heart failure and pulmonary hypertension does not develop if defect is <1.25 cm2
This unrepaired defect may lead to Pulmonary hypertension
Pulmonary hypertension may occur in unrepaired Patent ductus arteriousus
What are characteristics of cyanotic heart disease?
Tetralogy of Fallot: Large Ventricular Septal Defect, Pulmonary Stenosis, RVH, Overriding aorta
What is Eisenmenget syndrome? What conditions is it common in? (3)
Pulmonary vascular resistance > systemic vascular resistance
Common in: ASD, VSD, PDA
Normal resting Pulmonary
Pressure vs Pulmonary Hypertension
Normal resting Pulmonary
Pressure: 12- 16 mmHg
Pulmonary Hypertension: > 25mmHg
Pulmonary Hypertension is what NYHA class? Pregnancy is (well/poorly) tolerated.
GROUP II: most commonly encountered in pregnancy
Pregnancy is CONTRAINDICATED
Treatment of Pulmonary Hypertension
Limitation of movement, Avoid supine position, O2, Vasodilators
Analgesia for pulmonary htn
subarachnoid, Avoid epidural analgesia
diagnositc criteria for peripartum cardiomyopathy
- Cardiac Failure in the last month or within 5 months of pregnancy
- No cause for the failure
- No heart disease before pregnancy
- Left ventricular systolic dysfunction
hallmark finding in idiopathic cardiomyopathy and treatment
Hallmark finding: cardiomegaly
TREATMENT
- NaCl is restricted
- Diuretics
- Hydralazine
- Digoxin
- Heparin
Diagnosis of peripartum heart failure
Chronic hypertension with superimposed Preeclampsia
. Basilar rales w/ nocturnal cough
. Sudden decline in activity
. Increase dyspnea on exertion
. Hemoptysis
management of peripartum heart failure
diuretics, antihypertensive, anticoagulant
What is the Duke criteria used for and what are the points?
diagnosis of infective endocarditis; positive blood cultures for typical organisms and evidence of
endocardial involvement
What are the maneuvers to raise vagal tone ablock the AV node?
vagal maneuvers - raise vagal tone ablock the atrioventricular node -‐ Valsalva maneuver -‐ carotid sinus massage -‐ bearing down -‐ immersion of the face in ice water
pre-excitation of the ventricles of the heart due to an accessory pathway known as the bundle of kent
A. Wolf-Parkinson-white syndrome
B. Supraventricular Tachyarrythmia
C. Ventricular Tachycardia
D. Inc. QT interval
A. Wolf-Parkinson-white syndrome
Manged with Vagal maneuvers, Intravenous adenosine, Electrical cardioversion
A. Wolf-Parkinson-white syndrome
B. Supraventricular Tachyarrythmia
C. Ventricular Tachycardia
D. Inc. QT interval
B. Supraventricular Tachyarrythmia
Associated with fatal ventricular arrhythmias and w/ intake of: Azithromycin, Erythromycin, Clarithromycin
A. Wolf-Parkinson-white syndrome
B. Supraventricular Tachyarrythmia
C. Ventricular Tachycardia
D. Inc. QT interval
D. Inc. QT interval