OB Complications I -Castro Flashcards

1
Q

What is Small for Gestational Age? How is this different from Intrauterine Growth Restriction (IUGR)?

A

-SGA is birth weight less than the 5-10th percentile for gestational age (diagnosis made at or after birth)

-IUGR relies on US biometry for estimated fetal weight less than the 10th percentile for GA
(or abd circumference < 10th percentile)

*both are based on weight/GA tables or growth curves

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2
Q

What is considered “preterm”?

A

< 37 weeks

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3
Q

What are some complications of IUGR?

A
  • Increased fetal and neonatal mortality
  • Increased neonatal morbidity (fetal distress, meconium aspiration, hyperviscosity syndrome, hypoglycemia, hypocalcemia, congenital anomalies)
  • Increased rate of neurodevelopmental disorders (eg cerebral palsy)
  • Increased incidence of hypertension, glucose intolerance and cardiovascular disease in later life
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4
Q

What is IUGR due to? What is the #1 cause of uteroplacental insufficiency that can lead to IUGR?

A
  • decreased cell number, decreased cell size or both
  • 1st trimester insults ==> dec cell number (anomalies, genetic defects)
  • Hypertensive disease is the #1 cause of uteroplacental insufficiency
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5
Q

What are some fetal causes of IUGR?

A
  • chromosomal
  • biochemical abnormalities
  • congenital malformations
  • congenital infections (TORcH)
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6
Q

What is normal weight gain for a woman with a normal BMI? What can happen if a woman does not gain enough weight?

A

25-35 lbs

inc risk of IUGR

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7
Q

How is IUGR diagnosed?

A
  • must have an accurate GA
  • estimate fetal weight by US
  • compare to population specific growth curves
  • clinical assessment of risk status (if fundal weight is > 3 cm off from normal –> perform US)
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8
Q

How are IUGR fetuses monitored?

A

serial US’s to assess fetal growth but try to not over-expose

NST and biophysical profile (BPP) or modified BPP (AFI+ NST) done twice weekly

Doppler velocimetry of umbilical and uterine arteries to determine uteroplacental vs fetal etiology

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9
Q

What is the management for IUGR?

A

look for underlying cause of growth restriction in mom’s history, nutritional status, occupation, history, US looking for anomalies and consider karyotype

–> treat/eliminate the cause of the IUGR

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10
Q

When would you deliver a fetus with IUGR?

A
  • Fetal testing is non-reassuring (decelerations, oligohydramnios or abnormal umbilical doppler studies)
  • The fetus is term or fetal maturity is present
  • No interval growth is present over 3 weeks
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11
Q

What is LGA? How is Macrosomia different from LGA? What are the causes of both?

A
  • LGA is EFW (est. fetal weight > 90th % for GA)
  • Macrosomia is EFW > 4000 or 4500 grams
  • causes? Maternal obesity or excessive weight gain, diabetes (esp gestational)
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12
Q

What are the potential consequences of LGA/macrosomia?

A
  • intrapartum problems (cephalopelvic disproportion/birth trauma/shoulder dystocia –> Erb’s Palsy)
  • at risk for childhood and adult obesity and glucose intolerance
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13
Q

When should LGA/macrosomia be suspected? How is diagnosis confirmed?

A
  • suspected with fundal height > 3 cm > than expected for GA (there are other causes)
  • diagnosis confirmed by ultrasound
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14
Q

What is the management of LGA/macrosomia?

A
  • address weight gain and glucose control
  • be prepared for shoulder dystocia if vaginal delivery is planned
  • individualize treatment

*elective c-section if EFW > 5000g recommended

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15
Q

What is intrauterine fetal demise (IUFD)?

A
  • death occurring in utero at or before birth after 20 weeks gestation
  • AKA stillbirth
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16
Q

What is the fetal death rate?

A

live deaths/1000 births

17
Q

How is IUFD diagnosed? What will happen if the mother does not deliver the fetus?

A

pregnant woman reports decreased or absent fetal movement –> US shows no cardiac activity

retained dead fetus may cause DIC after 6 weeks

18
Q

What lab tests are recommended for IUFD work-up?

A

blood type, Rh and antibody status; hemoglobin A-1C; VDRL; ANA and lupus anticoagulant; Kleihauer-Betke (fetal hemorrhage); urine toxicology; Cord blood IgM; maternal antibody titers to rubella, CMV, herpes and parvovirus; fetal karyotype

LOOK for a cause* –> avoid this in the future