OB (4/10) Flashcards
oxygen uptake in fetus is ________x that of the adult, but decreases significantly with hypoxemia
2
fetal circulation directs oxygenated blood to the _______________ & ___________ and deoxygenated blood to the ____________ & ________
Brain; heart; umbilical circulation; placenta
describe the flow of fetal circulation starting at the placenta
(oxygenated) placenta –> liver –> portal sinus and ductus sinus –> IVC –> right atrium –> foramen ovale –> L. atrium –> L ventricle –> aorta –> brain and myocardium (ensuring they get the highest concentration of O2 blood)
(deoxygenated blood) coming in from lower extremities and SVC –> R. ventricle –> pulmonary trunk –> ductus arteriosus –> descending Ao –> lower extremities and hypogastric arteries –> returns to placenta via umbilical arteries
the fetal oxyhgb dissociation curve is shifted to the ______________ with respect to the adult (non-pregnant) form and the pregnant womans oxyhgb curve lies to the ____________ of the nonpregnant
left; right
what would you expect to happen to the pregnant mothers oxy-hgb dissociation curve with hyperventilation
move left
why does fetal blood have higher affinity for O2 than the mothers
fetal hgb has no B-chain so has higher affinity
what are the 3 major shunts of fetal circulation
- ductus venosus
- foramen ovale
- ductus arteriosus
the fetal circulatory shunt bypasses the liver via the ________________
ductus venosus
_________________ is the shunt in fetal circulation which bypasses pulmonary circulation
ductus arteriosus
what is the purpose of oxytocin (“pitocin”)
- induce or augment labor
- induce uterine contractions
- maintains uterine tone
- given postpartum to increase uterine tone and stop bleeding
dose of oxytocin when used to augment/induce labor
3-40 miliunits/min titrated to achieve normal contraction pattern
dose of oxytocin postpartum to decrease hemorrhage
10-40 units per IVF bag or 10 units IM
common s/e of pitocin
- uterine hypertonicity
- N/V
_______________ are what change the size of the cervix
contractions
what is the black box warning for oxytocin
not indicated for elective labor
(but this is what we primarily use it for…)
serious side effects of pitocin
- anaphylaxis
- SIADH
- HTN
- arrhythmias
- postpartum hemorrhage
- pelvic hematoma
- vaginal or cervical laceration
- abruption
- uterine rupture
- uterine tetany
what is the laboring dose of oxytocin
0.5-1 mU/min
what dose of pitocin is equivalent to spontaneous labor
6 mU/min
what are the different drugs used for uterine atony
- oxytocin
- methylergonovine (methergine)
- hemabate
- misoprostol (cytotec)
if you have given pitocin for uterine atony after delivery, but the uterus is still boggy what drug should you give
methergine