OA and RA

Question 1

Modifiable risk factors for OA?

Answer 1

body mass
joint injury
occupation
muscle weakness
structural misalignment

Question 2

Common comorbidities of RA?

Answer 2

CVD
infections
mental health conditions
malignancies

Question 3

OA diagnostic guideline for hip?

Answer 3

Hip pain + at least 2 of:
ESR >22
osteophytes on radiograph or joint spacing on radiograph

Question 4

OA diagnostic guideline for knee?

Answer 4

Knee pain + osteophytes on radiographs + at least 1 of:
>50 yoa
morning stiffness

Question 5

OA diagnostic guideline for hand?

Answer 5

hand pain/aching/stiffness + hard tissue enlargement of 2 or more of 10 selected joints +

Question 6

What are the 4 components of the classification criteria for RA?

Answer 6

joint involvement
serology (antibodies)
acute phase reactants (CRP, ESR)
duration of symptoms

Question 7

Nonpharmacologic recommendations for the management of hand OA?

Answer 7

• evaluate ability to perform activities of daily living
• instruct joint protection techniques
• provide assistive devices to help patients perform ADLs
• instruct in use of thermal modalities
• provide splints for patients with trapezemetacarpal joint OA

Question 8

Nonpharmacologic recommendations for the management of knee OA?

Answer 8

• CV (aerobic) and/or resistance land-based exercise
• aquatic exercise
• lose weight (if overweight)
• manual therapy
• psychosocial interventions
• tai chi programs
• acupuncture
• transcutaneous electrical stimulation
• walking aids as needed

Question 9

Nonpharmacologic recommendations for the management of hip OA?

Answer 9

• CV and/or resistance land-based exercise
• aquatic exercise
• lose weight (if overweight)
• thermal agents
• psychosocial interventions
• walking aids as needed
• manual therapy + supervised exercise

Question 10

efficacy of acetaminophen vs placebo for OA?

Answer 10

“of questionable clinical significance” vs placebo

relative improvement from baseline 5% vs placebo

Question 11

efficacy of acetaminophen vs NSAIDs for OA?

Answer 11

acetaminophen less effective for pain, functional status or global assessment

NSAIDs more likely to experience adverse GI event (RR 1.47)

Question 12

when to take NSAIDs instead of acetaminophen for RA?

Answer 12

when acetaminophen not sufficient.

Lowest dose for shortest duration!

Caution:
elderly
renal disease
CVD

Question 13

In a Cochrane review, how did topical NSAIDs compare to oral NSAIDs?

Answer 13

No difference in efficacy of topical vs oral NSAIDs

GI adverse events less likely in topical

50% pain relief over 8-12 weeks