OA Flashcards
What is osteoarthritis?
a disease of synovial joints including mechanical, inflammatory, and metabolic factors which results in degeneration of the joint
How many Australians does OA currently affect?
10%
Where is OA most commonly seen within the body?
knee
Why is nutrition from synovial fluid so important to joints?
the region is avascular so it is the only source of nutrition
hence movement and exercise is so important for maintaining joint health
Can collagen be replaced once lost?
not adequately
Can proteoglycans be replaced once lost?
yes
What is the role of the synovial membrane?
remove particulate matter by phagocytosis
provide nutrition
synthesise components of synovial fluid
What is subchondral bone?
bone underlying the articular cartilage
What is primary OA?
OA not resulting from injury or disease
What are some risk factors of primary OA?
obesity 55-60 years of age genetic inheritance (hand & hip OA) female (knee OA) alignment inactivity
What is secondary OA?
OA that occurs in response to injury or disease
What are some risk factors of secondary OA?
injury/trauma
sport
occupation
What is the pain mechanism of OA?
primarily peripheral nociceptive
23% experience neuropathic pain
How does OA pain normally present?
intermittent & predictable (relating to mechanical)
How is OA diagnosed?
> 45 years
activity-related joint pain
no am stiffness or am stiffness <30 minutes
When would we refer a patient for imaging after diagnosing OA?
if a more sinister underlying condition is suspected
if it will change our treatment