O2 Therapy Flashcards
Cardiopulmonary system compensates for hypoxemia by :
- increasing ventilation and cardiac output
Hypoxemia causes:
- pulmonary vasoconstriction
- pulmonary hypertension
three basic ways to determine whether a patient needs
O2 therapy :
• use of laboratory measures such as arterial blood gas testing
• based on the specific clinical problem or condition
• may cause tachypnea,
tachycardia, cyanosis, and distressed overall appearance, and
therefore bedside assessment can help identify such a need
Laboratory measures for documenting hypoxemia include :
■ hemoglobin saturation
■ partial pressure of oxygen (PaO2),
commonly a used threshold for hypoxemia:
PaO2 - <55 to 60 mm Hg
SaO2 - <87% to 90%
condition formerly known as oxygen toxicity is currently termed
hyperoxic acute lung injury.
Hyperoxia
PaO2 greater than 300 mm Hg
In hyperoxia, threshold appears clinically important at
PaO2 of greater than 150 mm Hg
Two factors determine the extent of harmful effects of O2:
• PaO2
• Exposure time
The toxicity of O2 is caused by
Overproduction of O2 free
radicals
Avoiding Oxygen Toxicity Limit patient exposure to 100% O2 to less than 24 hours whenever possible. High FiO2 is acceptable if the concentration can be decreased to 70% within 2 days and 50% or less in 5 days.
High PO2 also is associated with
• retinopathy of prematurity (ROP)
• bronchopulmonary dysplasia in infants.
Although the toxic effects of high
O2 concentrations can be serious, it is not FiO2 but rather PO2 that
results in such harmful effects
Oxygen toxicity
■ Fio2 > 60% longer than 36 hrs
■ Fio2>80%longer than 24 hrs
■ Fio2>100%longer than 12hrs
The user judges the performance of an O2 delivery system by answering two key questions:
● How much O2 can the system deliver (FiO2 or FiO2 range)
● Does the
delivered FiO2 remain fixed or vary under changing patient
demands?