O2 And Co2 Transport

Question 1

Describe how co2 is carried in the blood

Answer 1

5-10% bound to amino acids
the rest carried in plasma as bicarbonate after HH equation
Carbonic anydhrase facilitates reaction 13,000 times
HB molecule accepts the H+ ion

Question 2

Describe how O2 And co2 are exchanged at the tissues

Answer 2

Pao2 is low in tissues, high in aterial blood
Pco2 is high in tissues, low in aterial blood
4 factors affect HB affinity for O2 + haldane effect
Co2 HH equation and enters plasma
O2 diffuses into the cell and enters the mitochondria

Question 3

Describe the movement of O2 and co2 in the lungs

Answer 3

Pao2 is 104 in alveoli, 40 in venous blood
Steep gradient
O2 joins HB and releases h+

Pco2 is 45 in venous blood, 40 in alveoli
Co2 soluble in solution (Henry’s)
Haldane effect reversed
HH equation is reversed

Question 4

Describe how O2 is carried in the blood

Answer 4

98.5% in HB forming oxyhemoglobin (releases h+ ion)
1.5 in plasma, not very soluble (Henry’s)
Positive cooperation gives S shape binding
Partial pressures of O2 in plasma determine HB saturation