O2 and CO2 transport

Question 1

what percent of O2 is carried by hemoglobin (Hb)?

Answer 1

98.5

Question 2

what type of binding does Hb have?

Answer 2

reversible binding

Hb +O2 “deoxygenated”&raquo_space;> HbO2 “oxyhemoglobin”

Question 3

Hb binds more O2 in places with a ____ pO2

Answer 3

higher

this allows for more HbO2

Question 4

Hb releases more O2 in places with a ___ pO2

Answer 4

lower

this mean less HbO2

Question 5

pO2 in pulmonary veins is 98%. This mean hemoglobin is __.

Answer 5

oxygenated: more HbO2 (~98%)

Question 6

pO2 in pulmonary artery is 40. This means hemoglobin is __.

Answer 6

deoxygenated: HbO2 (~75%)

Question 7

what are some factors that determine affinity (tightness) of Hb for O2

Answer 7

pH
pCO2
temperature

Question 8

When pH decreases, Hb’s affinity for O2 ___.
What happens to O2?

Answer 8

decreases

O2 is released from Hb

Question 9

when there is alot of CO2 in a tissue, Hb’s affinity for O2 ___.
What happens to O2

Answer 9

decreased

O2 is released from Hb

Question 10

What is the enzyme that catalyzes this reaction?

CO2 + H2O → H2CO3

Answer 10

carbonic anhydrase

Question 11

What happens during the Cl- shift

Answer 11

Cl- is exchanged with HCO3-

HCO3- into cell
Cl- out of cell

Question 12

What are the 3 way CO2 travels in the body

Answer 12

dissolved CO2
carbaminohemoblobin (HbCO2)
bicarbonate ions (H2CO3 or HCO3-)