Nystagmus and related oscillations Flashcards

1
Q

define nystagmus

A

an osicillation of eye movements
rthmic movement
could be horizontal vertical or rotational

could be unilateral or bilateral

  • can be defined as a pursuit that takes the eye away from fixation and then a correwctive movement

happens in 2 satges - there is a slow eye movement which breaks fixation and then a corrective movement

the slow eye movement taking the eye away from fixation is where the pathology is

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2
Q

what are the types of nystagmus

A

physiological nystagmus

infantile nystagmus syndrome

acquired nystagmus

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3
Q

what are the types of physiological nystagmus

A

end point nystagmus - you ask a pt to look in extreme gazes e.g. extreme right or extreme left and you ask them to hold that position n- they have a break of fixation

usually results in a fine jerk with moderate frequency

okn- re fixation when looking at a moving object

caloric - when pouring hot or cold water into the ears you get nystagmus movement - - COWS- cold water intiates oppoiste nystagmus whilst cold water initates and opposite nystagmus

post rotation - if the body is moving quickly and then you stop the body suddenly - the eyes continue to roll for a few seconds

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4
Q

what things need to be noted on investigation of nystagmus

A

infantile vs acquired

position of nystagmus
- weather it is primary position nystagmus- is it present when looking in a straight ahead position or gaze dependent

waveform characteristics should also be noted

jerk nystagmus has slow phase which breaks the fixation and a and a quick phase to correct (that is a saccade) - we label it acccroding to the quick phasse not the smooth pursuit of it drifiting outwards

pendular - slow phase that takes you out of fixation and then a quick phase to regain fixation - so two pursuits back to back rather than a smooth pursuit followed by a saccade back which happens in jerk nystagmus

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5
Q

what are subgroups of infantile nystagmus syndrome

A

infatile idiopthaic :

  • horzionatal jerk/pendular

null zone - nystagmus slows down in that area compared to other areas

reduced vision

inherited in 50% of cases

sensory deprivation - happens if child loses vision quite early in life

  • pendualr #
    roving eye movements- look in different directions- both eyes moving together

manifest/laten (fusion maldevelopment nystagmus) - usually happens in children who have congential esotropia

horizontal jerk
fast phase towards fixing eye

worse on occlusion
chnages direction depending on which eye is fixing

spasm nutans

  • unilateral, bilateral, horizontal or multiplanar
  • head nodding
  • troticollis
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6
Q

what questions need to be considered in acquired cases of nystagmus

A
  • pathological
  • truly acquired?
  • description:

effect on fixation (vestibular , central or peripheral)

other signs and symptons

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7
Q

what are adult nystagmus symptons

A

oscillopisa- i.e. feeling that their world is moving - everything is shifting - moving upwards , downwards or sideways

non - specific symptons

blurred vision

jumbled vision ‘

imbalance

no symptons
- present for as long as he can remeber

typical of infantile nystagmus

incidental finding by an optician

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8
Q

what should you first do when investigation nystagmus

A
  • get a pateitn to look in the distance at a target with both eye open in primary position
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9
Q

what would the nystagmus look like if plotted on a graph

A

pendualr nystagmus - to and fro movements arre similar

slow phase and fast phase = jerk nystagmus

also need to document in what plane the eyes are moving e.g. horizontal/vertical/torisonal

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10
Q

what needs to be documented in terms of nysgatmus descri0ption

A

plane eyes are moving in

in what direction are the eyes noving e.g same direction in both eyes= conjugate

opposite direction = disjugate

jerk nysgatmus = described by the description of the fast phase

are both eyes doing the same thing

only in one eye = INO, SO, Myokymia

bilateral

different intesity between eyes = disscoiated

different waveform between eyes

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11
Q

what is disjugate nysgatmus

A

look at one eye at a time - e.g. right eye is moving horzionally and left eye is moving a vertically

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12
Q

what needs to be documeneted in terms of how easy it is to see the nystagmus

A

document - amplitude of the movement

measured in dgerees

graded as small, medium large

frequency of the movement

  • beats within time
  • graded as low, medium and high

intensity= amplitude x frequency

graded as low , medium and high

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13
Q

what should you observe before getting the patient to move their eyes

A

observe nystagmus before they move their eyes

varies with time

may change direction (PAN) -periodic alternating nystagmus - i.e. you look at the patient and then a few moments the direction of nystagmus changes - it is a specific type of horizontal nystagmus for a few moments it may be right beating but then it will become left beating -

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14
Q

what is alexanders law

A

intensity of nystagmus increased with gaze in the direction of the fast phase

pendular nystagmus can change to jerk nystagmus

jerk nystagmus can change its characteristics

upon near fixation - the intensity of nystagmus may reduce (especially in infantile nystagmus cases)

e.g. if they have right jerk nystagmus and you get them to look to the right the right jerk nystagmus will get worse

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15
Q

how are ocular movements recorded

A

recorded diagramatically with a 9 square grid with the

the direction of the arrow tells you weather it is horizontal or vertical

the intensity is the amount of arrows put

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16
Q

when does infantile nystagmus happen

A

before 3 months for childhood nystagmus

important in ch to note if

  • parents observe any change in the childs behaviour

distress

lighting condition

any AHP

17
Q

what needs to be documented in the history

A

what can the child see ]

  • any coneren over vision

schooling

preganacy history

  • alcohol
  • recreational drugs
  • comp0lications

Family History
- albinism
- retinal dystrophy
- nystagmus

18
Q

what 3 things need to be done in the investigation of childhood nystagmus

A
  • visual acuity
  • orthoptic assesement ]
  • refraction
19
Q

what are things that can affect the visual pathway but present as nystagmus

A

corenal enlarged (congential glaucoma)

clarity of the media

  • conreal opacities
  • catarcts
    virteous opacities ]

iris transillumination defects

  • albinism
  • aniridia

pupil reaction

  • paradoxcial response
  • retinal dystrophy

sluggish pupil reactions

  • lebers amaurosis
  • optic nerve hypoplasia
20
Q

what disroders of the anterior visaul system can present as nystagmus

A

retina
retinopathy of prematurity
retinal folds
coloboma

  • the presence of the fovea
  • hypoplastic in albinism

the optic nerves
optic nerve hypopolasia

21
Q

what is the differential diagnosis in the absence of any obvious media or retinal abnormality

A

most cases of infatile nystagmus are the result of bilateral sesnory abnormaility affecting the anterior visual pathway

  • ocular albinism
  • oculocutaneous albinism
  • optic nerve hypoplasia
  • lebers congential amaurosis
  • rod monochromnatism
  • congential stationary night blindness
    idiopathic infantile nystagmus’

electrodiagnostic assement would be done

22
Q

what electrodiagnostic assesments would be doen

A

ERG
absent response

lebers amourosis

absent b wave
- x linked retinoscvhsis

csnb

absent cone response
rod monchromatism

VEP
- crossed asymmetry

  • albinism
  • diminished response
  • optic nerve hypoplasia
23
Q

what are the features of infantile nystamus

A

features usually within the first 3 months , later onset possible with acquired visual disease

  • jerk/pendual waveform
  • horzionatal in all gaze postions

symmetrical

bilateral’
- usually has a null point and dapens on convergence

24
Q

how can you use alexanders law to dertmine what idrection the nystagmus is

A

ask pt to look right and left - where the nystagmus increases is the direction of the nystagmus

25
Q

what is laetnt and manifest latent nystagmus

A

latent nystagmus

horizontal jerk nystagmus

absent when both eyes are open

present when the light stimnulus to one eye is reduced

bilateral

symmetrical

conjugate

26
Q

what is LN/LMN associated with

A

intensity

-increases on covering wither eye

  • increases on abduction and decreases on adduction

a face turn to the side of the fixing eye is commonly seen

binocular single vision
- absent or poor in most patients

commonly associated with

infantile esotropia

or dvd

27
Q

what are acquired forms of childhood nystagmus

A

spasm nutans

nystagmus with intracranial disease

nystagmus with ipsilateral visual loss

28
Q

what do you get with spasmus nutans

A

asymmetrical nystagmus

involountary head movements

abnormal head posture ]

(the triad of spasm nutans)

29
Q

what are features of spasm nutans

A

onset between 3 months- 18 months of age

nystagmus - pendular waveform

horizontla, vertical or torsional

assymetricla- appears unilateral

low amplitude - fast frequency

varies considerably in different postion sof gaze

if head nodding is pressent , the intensity increases if the head is imbolised

30
Q

is spasm nutans a perement thing

A

no- may last from a few eeks to several years

head movement - proceeds the onset of nystagmus

involountary nodding or shaking movement

opposite phase of the eye movement

do not appear to compensate for the nystagmus as they are of different frequency

dissapera during sleep

31
Q

what is a common reason for nystagmus in adults

A

peripheral vestibular nystagmus

  • features - symptons of vestibular dysfunction

jerk nystagmus

horizontal/rotary

shimmering
small amplitude, fast frequency

unidirectional
- nystagmus beats in the same direction irresepective of the direction of gaze
alexanders law

fast phase away from the lesion

often transient

enhanced by removing fixation/clsoing eyes

causes

infection

toxic reactions

trauma

inflammation

32
Q
A