Nutrtion 2 Flashcards
What does active transport of calcium use?
Calbindin 9k
Calcium absorbed by?
Active transport and passive diffusion
Fxns of calcium
Bone mineralization and cell signailing
Best source of calcium?
Dairy
Hypo calcemia causes?
tetany and osteoprosis
Hypercalcemia symptoms?
fatigue, hallucination and constipation
Causes of hypercalcemia?
Hyperthyroidism and increased calcium intake
Fxn of phosphorus
enzyme regulation (covalent modification)
phospholipid
ATP and cAMP
Best sources of phosphorus
Animal products
Hypophosphetemia causes?
Arrythmias
Hyperphosphetemia is connected to?
Hypo calcemia
Magnesium sources
Plants
fxns of magnsium
cofactor, muscle relaxer and PTH secretion
Hypermagnesmia causes
slurred speach and migraines
Hypomagnesmia causes?
Muscle weakness
Best source of sodium?
Salt NACL
Sodium fxn?
Fluid balance and nerve transmission
Hyponatremia?
Difficiency of sodium that causes muscle cramps
Hypernatremia is?
Excess sodium. Causes hypertension
Potassium fxns
Fluid balance and nerve transmission
What three minerals fxn in fluid balance and nerve transmission?
Na,K,Cl
Source of chloride?
salt NaCl
Hyperkalemia
too much K, causes arrythmias
Hypokalemia
not enough K, causes arrythmias
best sources of K
banana, canteloupe, sweet potatoes
Major mineral intake?
greater than 100mg/d
Chloride fxns
HCl, fluid balance and nerve transmission
mineral absorption inhibited by?
Phytate, oxalate, tannins
Iron tansported out of enterocyte by_______ and uses ____ to accomplish this.
Ferroportin, uses copper
Non heme iron sources?
plants and supplements
Non heme iron digested by_____ and requires_____to do this?
Ferrireductase and it requires vit C
Nonheme iron absorbed by?
facilitated diffusion, DMT
Iron toxicity causes?
hemochromatosis and organ damage
iron fxns
cytochromes and oxygen transport
Storage protein of iron?
ferritin
ferritin found in?
liver, spleen, bone marrow, and enterocyte
Iron deficiency symptoms?
Pallor, fatigue and decreased immune system.
Iron deficiency causes?
Microcytic anemia
People most at risk fro iron dificiency?
6mo-2yr, boys 10-19, male runners, women 10-44, all female athletes.
Iron dificiency correlates with what other mineral?
Copper
what transports in blood?
transferrin
What is more absorbed heme or non heme?
heme
Heme absorbed by?
facilitated diffusion, Hcp1
heme sources?
fish and beef
A difficiency of what 3 minerals causees decreased immune system?
Copper iron and zinc
Best source of zinc?
seafood
zinc fxns
folate digestion and heme
zinc deficiency
decreased taste, dermititis and decreaed immune system.
Zn toxicity cause?
metallic taste
zinc supplements
decreased absorption, folic acid.
copper toxicity
Wilson’s disease
Wilson’s disease causes?
keyser fleisher rings
copper fxns
atp, collagen crosslinking, ferroportin.
Copper deficiency
Skin and hair depigmentattion, decreased immune system.
Genetic copper def is menkes syndrome
best source of selenium
brazial nuts
Selenosis causes?
Too much selenium and causes brittle nails
selenium fxn
cofactor for glutathione peroxidase and t4-t3
iodide toxicity
burning mouth and throat, hypothyroidism
iodide def
goiter
Selenium def?
Keshans disease (heart disease in kids), Kashin becks disease (osteoarthrits), insulin resistance (prevalent in china and mongolia). Selenium deficiency depends on soil content.
Crommium fxns
insulin secretion
crommium def causes?
insulin resistance, prevalent in mongolia and china
iodide fxns
part of t3 and t4
manganese fxn
cofactor
molybdenum fxn
cofactor in s metabolism and uric acid syntheisis
best source of molybdenum
plants
Molybdenum toxicity causes?
gout
flouride toxicity
mottling of teeth and pitting of bones
fxn of flouride
bone mineralization
sources of flouride
flouridated water and toothpaste
flouride def causes
cavities and osteoprosis
what enhances mineral absorbtion
acidic environment
trace mineral amount
less than 100 mg/d
What minerals aid in bone mineralization?
folate, calcium, phosphorus, sodium
What is linked to hypocalcemia
hyperphosphetemia, hypernatremia, hypomagnesmia