Nutritional/Metabolic Disorders Flashcards

1
Q

Describe Vitamin A & why it’s important

A

Fat soluble, important for vision, immune system, kidney, skin & mucous membrane function

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2
Q

Where is Vitamin A found?

A

In liver, fish oil, fortified milk, eggs

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3
Q

What is the precursor to Vitamin A? & where is it found?

A

Beta carotene (fruits & veggies)

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4
Q

Whose at risk for Vitamin A def?

A
  • Elderly
  • Alcoholics
  • liver dz
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5
Q

S/S of Vitamin A def

A
  • Night blindness
  • Dry skin
  • Poor wound healing
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6
Q

Vitamin A Dx

A

via serum level

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7
Q

Vitamin A tx

A

Supplements

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8
Q

What is Vitamin D needed for?

A

helps bones absorb Ca++

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9
Q

Where is Vitamin D found?

A

fortified milk, or produced w/ exposure to sunlight

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10
Q

Whose at risk for Vitamin D def?

A
  • Elderly
  • Infants
  • Low sun exposure
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11
Q

Vitamin D def leads to:

A
  • rickets (dz of children- causes distortion of bones, dental hypoplasia)
  • Osteomalacia (defective bone mineralization in adults)
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12
Q

Vitamin D Dx

A

Serum Vitamin D level, hypocalcemia

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13
Q

Vitamin D Tx

A
  • Sunlight
  • Supplements
  • Underlying condition
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14
Q

What is another name for Thiamine?

A

Vitamin B1

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15
Q

Function of Thiamine?

A

Enables the body to use CHOs as energy- esp important for nerve, muscle, heart function

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16
Q

Where is Thiamine found?

A

In beef, liver, beans, nuts, rice

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17
Q

Who is at risk for Thiamine Def?

A

alcoholics

18
Q

Thiamine Def leads to:

19
Q

What is Wet Beriberi?

A

periph vasodilation w/ HF, dyspnea, pulm edema

20
Q

What is Dry Beriberi? & two conditions associated w/ it.

A

motor & sensory neuropathy (pain, paresthesia),
- Wernicke encephalopathy - Korsakoff syndrome

21
Q

S/S of Wernicke encephalopathy

A
  • Nystagmus
  • Ataxia
  • Confusion
22
Q

S/S of Korsakoff syndrome

A
  • Amnesia
  • Confabulation
  • Impaired learning
23
Q

Thiamine Def Dx

A

by giving thiamine- symptoms improve very quickly (though there is a serum test)

24
Q

Thiamine Def Tx

A

Parenteral Thiamine

25
What are other vitamins that can be def in alcoholics?
- Riboflavin (B2) - Pantothenic acid (B5) - B6 - Niacin - Biotin - Folate
26
Why is Vitamin C important?
Needed for the development & repair of all body tissues
27
Where is Vitamin C found?
- Citrus - Strawberries - Broccoli - Greens
27
Whose at risk of Vit C def?
- Alcoholics - Lower SES - Elderly
28
Vit C def leads to:
Scurvy: swollen, bleeding gums; easy bruising, brittle hair, slow healing wounds
29
Vit C Dx
decr plasma levels
30
Vit C Tx
supplements
31
Lactose Intolerance Dx
Usually self dx but can be tested w/a Hydrogen Breath Test
32
32
What usually breaks down lactose?
Lactase - produced by cells in the lining of the small intestine
33
S/S of Lactose Intolerance
- Bloating - Abdominal cramps - Flatulence
33
What is Lactose Intolerance/Lactose Def?
Impaired ability to digest lactose, a sugar found in milk & other dairy products
34
When there is loss of PAH activity, what happens?
phenylalanine accumulates leading to brain toxicity
34
Lactose Intolerance Tx
synthetic lactase or elimination of all milk products
35
What is Phenylketonuria (PKU)?
A genetic inborn error of metabolism characterized by the presence of a nonfunctional hepatic enzyme phenylalanine hydroxylase
35
What does PKU do?
converts the AA phenylalanine (PHE) into tyrosine
36
What secondarily happens to phenylalanine?
metabolized into phenylketones that are excreted in urine