Nutritional Diseases - W8

Question 1

Scurvy aka

Answer 1

Barlows disease or hypovitaminosis C

Question 2

Scurvy is associated with ___ ____ deficiency of Vit. C

Answer 2

long term

Question 3

Normal Vit. C dose?

Answer 3

75mg adult females

90mg adult males

Question 4

how much Vit C required to prevent scurvy?

Answer 4

10mg

Question 5

Vit C important b/c forms (3)

Answer 5

1. collagen
2. osteoid
3. endothelial linings

Question 6

Deficiency of _____ _____ & fragile ____ ____

Answer 6

intercellular cement & fragile blood vessels

Question 7

Bone _____ ceases

Answer 7

formation

Question 8

Absorption proceeds ?

Answer 8

osteoporosis

Question 9

MC in babies ___ - ____ months

Answer 9

8-14 months

Question 10

Elders have scurvy if?

Answer 10

diet is compromised

Question 11

Latent period?

Answer 11

4 months

Question 12

Spontaneous hemorrhage?

Answer 12

capillary fragility

Question 13

Scurvy: clinical findings (recognize)

Answer 13

cutaneous petechiae
bleeding gums
melena, hematuria
joint swelling
irritability 
pain 
frog leg position

Question 14

Dense zone of provisional calcification =?

Answer 14

White line of FRANKEL (delayed conversion to bone)

Question 15

Ring epiphysis

Answer 15

Wimbergers sign

Question 16

radiological findings of scurby?

Answer 16

Pelkens spurs
Scorbutic zone
Suberiosteal hemorrhage

Question 17

Acromegaly is a ______ disease

Answer 17

endocrine

Question 18

Increase GH in the ____ _____ adenoma

Answer 18

anterior pituitary

Question 19

GH activates ___ _____

Answer 19

bone growth

Question 20

Acral

Answer 20

means Hands

Question 21

clinical findings of acromegaly?

Answer 21

thick skin - heel pad
skull/facial changes
large hands
ADI

Question 22

Acromegaly - predisposed to ________ changes

Answer 22

degenerative

Question 23

Facial Changes?

Answer 23

large flat forehead
thick tongue
prominant cheek bones
large protruded mandible

Question 24

Management of acromegaly? (2)

Answer 24

surgical resection of microadenomas & radiation therapy

Question 25

Hyperparathyroidism is a _______ disease

Answer 25

metabolic

Question 26

Overactivity of parathyroid gland releases ______ hormone?

Answer 26

osteoclastic (PTH)

Question 27

How many types of hyperparathyroidism?

Answer 27

3

Question 28

Primary HPT: MC cause of ______ & ______

Answer 28

hypercalcemia & parathyroid adenoma

Question 29

Scondary HPT: complication of ______ ______

Answer 29

renal disease

Question 30

Secondary HPT: constant Loss of ____ and _____. Stimulate PT release.

Answer 30

Ca, and P

Question 31

Tertiary HPT

Answer 31

Dialysis patient

Question 32

Clinical findings of Tertiary HPT

Answer 32

- Female 30-50 yrs - weakness, lethargy, polydipsia, polyuria - calculus formation in kidneys

Question 33

Increased PTH, stimulates ______ _______. and ____ and __ accumulates in blood. _______ is more readily excreted than calcium

Answer 33

osteoclastic resorption. Ca+ and P | Phosphorus

Question 34

HPTH: ***** hyper______ and hypo_______.

Answer 34

hypercalcemia and hypophophatemia

Question 35

HPTH Hallmark?

Answer 35

subperiosteal bone resorption of the outer cortex at the ligament an tendon insertion points

Question 36

brown tumors (2)?

Answer 36

1. osteoclastic giant cells | 2. cyst-like destructive bone lesions

Question 37

subperiosteal resorption

Answer 37

xray finding for HPTH

Question 38

HPT hits these locations?

Answer 38

1. second and third digits of hand 2. undersurface of distal clavicle 3. radial margins of the middle and proximal phalanges HANDS AND DISTAL CLAVICLE **

Question 39

Outer cortical erosion for HPT description?

Answer 39

irregular, frayed | lace-like appearacnce

Question 40

Subarticular bone resorption (3)

Answer 40

widens joint space osteolysis AC joint, symphysis, SI joint

Question 41

Salt and Pepper skull/pepper/pepper-pot skull

Answer 41

HPT

Question 42

HPT affects (3)

Answer 42

fingers, clavicle, skull

Question 43

HPT in spine ? ****

Answer 43

rugger-jersey spine (horizontal stripes) seen in vertebral body

Question 44

Target sites for HPT (5)

Answer 44

1. hands 2. skull 3. spine 4. pelvis 5. shoulders

Question 45

hypoparathyroidism deffinition?

Answer 45

accidental removal of parathyroid glands during thyroid surgery

Question 46

Hypoparathyroidism is associated with?

Answer 46

hypocalcemia and hyperphoshatemia