Nutrition and Diagnosis-Related Care Flashcards
Cancer that starts in the glands
Adenocarcinoma
Benign growth that may or may not grow into cancer
Adenoma
Process of stopping a tumor from growing new blood vessels
Antiangiogenesis
Most common form of skin cancer - primary cause: sunlight exposure
Basal cell carcinoma
Treatment to stimulate or restore the immune system to fight infection and disease and lessen side effects that may be caused by some cancer treatments
Biotherapy (also known as biological therapy or immunotherapy)
Abnormal, uncontrolled growth of cells in a lump or mass that also destroys normal tissue
Cancer
Encompasses 80-90% of all cancers; involves epithelial tissue and coverings of internal and external surfaces; includes skin, lungs, colon, stomach, breast, uterus, and tongue cancers
Carcinoma
Use of medication to kill malignant cells
Chemotherapy
Permanent removal of cancer from the body
Curative therapy
GI carcinoid tumor, pancreatic islet cell carcinoma, parathyroid cancer, pituitary tumor, and thyroid cancer are all examples of what types of cancers?
Endocrine system cancers (aka: adrenocortical carcinomas)
Anal, bile duct, colon, esophageal, gallbladder, GI carcinoid tumor, liver, pancreatic, rectal, small intestine, and stomach cancers are all what type of cancer?
GI cancers
Cervical, endometrial, ovarian, vaginal, and vulvar are all what type of cancer?
Gynecological cancers
Cancer where bone marrow-produced abnormal WBCs crowd out normal WBCs, RBCs, and platelets
Leukemia
Penile, testicular, and prostate cancers all are what?
Male reproductive cancers
Tumors affecting the meninges
Meningiomas
Rare cancer affecting the lining of the chest, heart, and abdominal cavity from exposure to abestos
Mesothelioma
Transfer of disease from one organ to another that is not directly connected to it
Metastasis
Targeted therapy to locate and bind cancer cells; can be used to delivery drugs, toxins, or radioactive material directly to tumor cells.
Monoclonal antibodies
Tumor composed of nerve cells
Neuroma
Most common bone cancer, which develops in new tissue of growing bones, affecting young people
Osteosarcoma
Treatment with high-energy rays to kill or damage cancer cells
Radiation
Cancer arising from bone or connective tissue
Sarcoma
Key dietary message to prevent cancer: promote intake of 3 main things…
Fruits, vegetables, and whole grains
Type of fiber that increases stool bulk
Insoluble fiber
Type of fiber that has a cholesterol-lowering effect
Soluble fiber
Dietary factors and physical inactivity contributes to what fraction of cancer patients?
1/3rd
In cancer patients, PIF (proteolysis-inducting factor), TNF (tumor necrosis factor), and LMF (lipid metabolizing factor) all promote _______.
Catabolism
Supplementation with this has been shown to stabilize weight in some cancer patients on oral diets experiencing progressive, unintentional weight loss.
Omega-3 fatty acid
Cancer drugs (type): these drugs kill cancer cells by stopping their growth or by making it hard for cancer cells to repair damage (side effects: n/v/hyperuricemia)
Alkylating agents
Cancer drugs (type): prevents nutrients and oxygen from being delivered to the tumor by reducing the number of blood vessels, thus hindering its growth
Antiangiogenic agents
Cancer drugs (type): DNA substrate analogs that lead to incorrect DNA synthesis affecting cancer cells (side effects: n/v/d/stomatitis)
Antimetabolites
Cancer drugs (type): used to relieve n/v after chemotherapy (side effects n/d/increased gastric emptying/drowsiness)
Antiemetics
Corticosteriods can cause 4 nutrition-related side effects:
1) hyperglycemia, 2) weight gain, 3) sodium/fluid retention, 4) calcium losses
Methotrexate is a _____ antagonist - it may decrease the absorption of these 4 components in food.
Folate; 1) lactose, 2) fat, 3) vitamin B12, 4) folate
Cancer drugs (type): these drugs correct the abnormal enzyme that causes cancer cells to grow out of control
Monoclonal antibodies
Bone cancer that most often occurs in the long bones of young people … and it most often spreads to ______.
Osteosarcoma, the lungs
Bone cancer staging:
Stage 1:
Stage 2:
Stage 3:
1: low-grade, no spread
2: high-grade, no spread
3: cancer of any grade that has spread beyond the bone
Most common method of treatment of bone cancer
Radiation
Most common drug used to treat bone cancer - helps to reduce bone breakdown, the risk of fracture/hypercalcemia, and bone pain
Bisphosphonates
Hematopoietic stem-cell transplantation is _____ _____ transplantation.
Bone marrow
Leukemias, lymphomas, and multiple myeloma are all:
Hematological cancers
The preparative regimen for bone marrow transplantation includes: ______ and _______ in order to: ______
High-dose chemotherapy and may also include total-body radiation; suppress immune reactions post-transplant
Most common indication for stem-cell transplantation
Hematological cancers
Post stem-cell transplantation - what diet would be most appropriate and why?
Neutropenic diet (low-bacteria)because the immune system is compromised and would not want to expose to a high-bacteria diet in an effort to reduce the risk of food-borne illness.
Post stem-cell transplantation - Provide _ - _ kcal/kg
30-35
Post stem-cell transplantation - Provide _ - _ g/kg protein
1.5-2.0
Neutropenic diet after bone marrow transplantation - follow for __ months or until immunosuppressive therapies are complete.
3
Neutropenic diet guidelines - name 5 things it entails
Hand washing, safe food temperatures
Avoid unpasteurized milk and juices, raw or undercooked foods containing heme protein, yogurt with active cultures, hot dogs/bacon/sausage/lunch meat, soft or mold-containing cheeses, unwashed produce, picked fish, etc.
Most common symptom of a brain tumor:
Headache
Headaches are the most common symptom of brain tumors because they:
Produce inflammation in the brain, compressing other parts of the brain as the tumor grows, causing swelling and pressure inside the skull
Non-neuronal cells in the brain that support and protect neurons in the the brain
Glial cells
A _____ is a tumor of neurological origin which constitutes over 50% of all brain cancers.
Glioma
_________ is the most frequent and devastating primary malignant brain tumor in adults.
GBM (glioblastoma multiforme)
Standard of treatment for GBM patients includes:
Surgical intervention, followed by radiation with chemotheraphy
Type of brain tumor that may be classified as benign or malignant and surgical excision is curative for most patients
Meningioma
The meninges covers and protects ____ and ____.
the brain and spinal cord
Brain cancer protein needs: for surgery =s _ - _ g/kg and RTX =s _ - _g/kg
1.2-1.5; 1.0-1.2
Why may you want to limit sodium in brain tumor patients?
to correct cerebral edema
Which are more common: primary or secondary brain tumors?
Secondary
Diagnosis of cancer is done by:
Biopsy
The process of measuring the amount that the cancer has spread or grown using medical imaging techniques
Staging
Stages of colon cancer: Stage 1: Stage 2: Stage 3: Stage 4:
1: Cancer is small, localized, and limited
2: Local spreading occurs within the organ and lymph nodes
3: Cancer cells invade through the organ and lymph nodes
4: Mets of the tumor occurs in other tissues of the body
Patients with ulcerative colitis and Crohn’s disease are at a higher risk for this type of cancer.
Colon
Risk factors of ______ cancer include: age >50, excessive alcohol intake, overweight or obese, smoking, western-style diet (high in red meat & fat and low in vegetables), family history, and inflammatory cytokines (cyclooxygenase-2 (COX-2) and prostaglandin).
Colon
A fecal occult blood test and sigmoidoscopy are used to help in diagnosis of ______ cancer.
Colon
In cancer of the small intestine, malignancy is generally found in the lower ______ and _______ with a ____ rate of mortality and ___ early symptoms.
Duodenum, Ileum, high, few