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Pharmacology > Nutrition > Flashcards

Nutrition Flashcards

1
Q

Vitamin K deficiency

A

Phylloquinone, phtomenadione, phytonadiane
defective blood clotting also could be created by long term use of antibiotics that destroy gut bacteria and halt synthesis

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2
Q

Vitamin K Use

A

correct bleeding due to vit k deficiency or USED IN WARFARIN OVERDOSE

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3
Q

Vitamin A deficiency

A

night blindness
eye problems
skin lesions lung gi and bone abnormalities
rarely seen except in 3rd world or pancreatic disease

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4
Q

Vitamin A Use

A

used for severe acne vulgaris

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5
Q

Vitamin A Adverse Effects

A

skin, bone, liver, gi problems at doses ocer 30mg

teratogenic category x drug

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6
Q

Vitamin D Deficiency

A

Used to enhance intestinal abs of ca iron mg phosphate and zinek and is activated by sun and enz conversionin the liver and kidney
Rickets in kids
osteomalacia in adults

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7
Q

Vitamin D adverse effects

A

excess destroys rneal tissue
causes muslce spasms
skeletal deformities due to alterations in ca metabolism

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8
Q

Vitamin E Deficiency

A

May be associated with low birth weights or anemia but is rare

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9
Q

Vitamin E adverse effects

A 
Increase risk of death (over 400),
 inc risk of bruisisg and bleeding (inhibit platelet agg and vitamin k antagonism)
 headache (could be from hemm stroke) 
diarrhea
fatigue
upper lmit at 1000mg per day
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10
Q

Vitamin E uses

A

Natural antioxidant to reduce cell damage
prophylactic against heart dsease and cancer but may actually inc mortality

used as antioxidant in plastics used in hip and knee rpelacements

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11
Q

Vitamin B1 - alternate name

A

Thiamine

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12
Q

Vitamin B1 Deficiency

A

Beriberi (CNS/cardio)

can occur in alchoholics, renal failure, and ifnants from mothers on rice diets

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13
Q

Vitamin B1 Use

A

used as an adjunct in acuete alc intox to prevent wernicke korsakoff syndrome

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14
Q

Vitamin B2 - alt name

A

Riboflavin

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15
Q

Vitamin B2 Deficiency

A

Essential part of FAD and FMN required for many reactions including synth of b6 and other vitamins
skin mucous membranes hematopeoeisis

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16
Q

Vitamin B2 Therapeutic use

A

none

17
Q

Vitamin B3 Deficiency

A

Niacin

Pellagra

18
Q

Vitamin B3 Use

A

vonversion from nad and nadh for use in redox reactions
NIACIN
hyperlipoprotenemia

19
Q

Vitamin B3 Adverse Effects

A

NIacin

Gi distress flushing and hepatotoxicity

20
Q

Vitamin B5 Alternate name

A

Pantothenic acid

21
Q

Vitamin B5 deficiency

A

Serves as the acyl group carrier for acetyl coa which is a primary source of carbons in the synth of fatty acids, cholesterol and acetycholine

neuromusc, endocrine, gi and cns

22
Q

Vitamin B5 use

A

none

23
Q

Vitamin B6 alternate name

A

pyridoxine

24
Q

Vitamin B6 deficiency

A

Rare- may lead to skin lesions, gi dysfunction, convulsions, carpa tunnel syndrome

25
Q

Vitamin B6 use

A

some drug tratments suggest suppelentation in combination with magnesium (L dopa penicillamine, isoniazid, contraceptives)

26
Q

Vitamin B12 alternate name

A

Cobalamin

27
Q

Vitamin B12 Deficiency

A

PERNICIOUS ANEMIA

NEUROLOGICAL SYNDROMES

28
Q

Vitamin B12 use

A

Pernicious anemia
acute cyanide poisonning
reduce brain atrophy in alzheimers
supplement after gastrectectomy or small intestine disease in strit vegans

29
Q

Vitamin B12 adverse effects/cautions

A

deficiency should not be treated with folic acid alone

30
Q

Vitamin C deficiency

A

cofactor in enz rection including collagen synth. serves mainly as antiox
scurvy (seen inelderly alcoholics infants from dficient mothers

31
Q

Vitamin C Use

A

Exploit antiox properties
use vs common cold
benifit in cancer or heart disease unsure

32
Q

Vitmin C risk

A

Use for long perioids can cause kidney stones

Pharmacology (5 decks)

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