Nutrigenomics Flashcards
Which is true?
A. RNA is more stable than DNA
B. Adenine and thymine are connected by 3 Hydrogen bonds
C. In the central dogma, DNA is replicated first
C
A = DNA is more stable
B. A & T : 2 H bonds only
Which is true?
A. DNA replication yields entirely new strands
B. DNA replication is bi-directional
C. the lagging strand is originally 3’ to 5’
B
A - semi-conservative
C - lagging strand is originally 5’ to 3’
the product of DNA transcription that serves as a template for protein synthesis
a. messenger RNA
b. transfer RNA
c. ribosomal RNA
A
the small form of RNA with covalently bound amino acid that reads the codon message on mRNA and incorporates the amino acid in the protein being synthesized
a. messenger RNA
b. transfer RNA
c. ribosomal RNA
B
Why are the essential amino acids (PVT TIM HALL) considered as essential?
Cannot produced by the body; must be part of the
diet
Which is false?
A. All DNA code for genes
B. The human genome project was completed in 2003
C. Celera Genomics funded HGP
A
differentiate nutrigenetics fr nutrigenomics
Nutrigenetics – about the genes acting on diet and other
environmental factors
Nutrigenomics – diet and other environmental factors
acting on genes, changing expression
differentiate Constitutive polymorphism from
Inducible polymorphism
Constitutive – polymorphism will always be expressed
Inducible – polymorphism will only be expressed if certain
conditions are present/met
classify whether nutrigenetics or nutrigenomics plays a key role here
A.Increased sensitivity to a component
B.Omega-3 down-regulation of cytokine gene
A. nutrigenetics
B. nutrigenomics
what is epigenetics
Refers to mitotically and/or meiotically heritable variations in gene expression that are not caused by changes in DNA
sequence
why is DNA methylation part of epigenetics?
the DNA sequence is not changed, but if methyl group is added, some expressed genes may be silenced
Which nutrigenomics strategy needs relatively bigger budget & research teams?
A. molecular nutrition and genomics
B. nutritional systems biology
C. equal
B
How does caloric restriction combine knowledge on transcriptomics and nutrition?
When aging mice were switched to caloric restriction, the transcriptome of the thymus reversed from an aged
profile to the profile of the younger mice
essentials of DNA microarray for transcriptomics
1.Labeled target nucleotides representing the mRNA
population of concern (by incorporating labeled
nucleotides into cDNA or cRNA that is transcribed from
mRNA templates);
2.Collection of numerous gene probes (microarray)
resveratrol & talin merge \_\_ and nutrition A. proteomics B. metabolomics C. BOTA D. NOTA
A
