Nutrient Metabolism Flashcards

1
Q

What is the benefit of drinking a “rehydration” beverage in patients with diarrhea?

A

they contain Sodium and glucose which benefits the absorption of glucose and water into the cells and helps to treat water and sodium losses from diarrhea

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2
Q

Which gut hormones/peptides reduce food intake/appetite

A

GLP-1 (glucagon like peptide - 1), OXM (oxyntomodulin), PYY (peptide tyrosine-tyrosine), & PP (pancreatic polypeptide

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3
Q

what is the purpose of CCK

A

it inhibits gastric emptying thus reducing food intake (does not effect meal frequency)

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4
Q

over view of Leptin

A

It is located in white adipose tissue and gastric mucosa. It is stimulated by food deprivation. With low levels of leptin, it increases energy intake and decreases energy expenditure

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5
Q

Overview of Ghrelin

A

Polypeptide located in the stomach. Stimulates growth hormone and results in increase of food intake.

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6
Q

Which foods should be limited to reduce nausea?

A

High fat and high fiber foods. Due to its prolonged time to leave the stomach

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7
Q

What other hormones inhibit gastric emptying?

A

Secretin and gastric inhibitory peptide

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8
Q

How much chyme is emptied into the cecum?

A

1500-2000 ml/d

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9
Q

Purpose of the ileocecal valve

A

To prevent back flow of fecal contents into the small intestines. When ileal pressure increases or food exits the stomach the ileocecal valve opens. It shuts when colonic pressure increases

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10
Q

Which type of fiber should be avoided with risk of bowel ischemia

A

Soluble and insoluble fiber

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11
Q

Vagotomy, gastric bypass, and destruction of the pylorus can cause what?

A

Dumping syndrome: symptoms include diaphoresis, weakness, dizziness, flushing, and palpitations

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12
Q

Where is the parietal cell located and what does it excrete?

A

Located in the body of the fundus and it releases HCl and intrinsic factor

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13
Q

What’s is the purpose of intrinsic factor?

A

Required for the absorption of B12.

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14
Q

Purpose of bile?

A

Required for digestion and absorption of bile. It helps to emulsify the fat and aids in the the absorption of digest fat into the intestinal mucosa

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15
Q

What is the significance of white stool?

A

This can indicate a biliary obstruction (bile being prevented from entering the colon)

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16
Q

Pancreatic juice is secreted where?

A

Into the duodenum

17
Q

Pancreatic juice contains what enzymes?

A

Pancreatic amylase (digests CHO), pancreatic proteases (digests PRO), and pancreatic lipase (digests FAT)

18
Q

What is the length of the small bowel?

A

~ 350-600cm

19
Q

Result of ileocecal valve resection

A

Small bowel contents enter too quickly into the Colin and some malabsorption may occur

20
Q

How many liters of fluid enters the small bowel daily?

A

9 total: 2 from dietary sources and 7 from GI secretions