NUTR2003 Flashcards
What is food security?
Physical, social and economic access to sufficient, safe and nutritious food that meets preferences/dietary needs at all times
What is food insecurity?
Lack of availability of nutritionally adequate and safe foods or limited ability to acquire acceptable food in socially acceptable ways
What are some causes of malnutrition?
- Lack of care or healthcare
- Lack of sanitation
- Lack of Support for mothers on appropriate child feeding
- Insufficient access to affordable nutritious food
What is alcohol?
A fermented carbohydrate; a product of the metabolism of sugar by yeast.
Where is alcohol metabolised?
liver
What are the negative effects of alcohol?
- dehydration
- increases HR
- peripheral vasodilation
- alters judgement
- thiamine deficiency
What are the functions of fat in the body?
- Insulation
- Structural component
- Roles in metabolism
- Vehicle for intake & absorption of fat soluble vitamins
What are lipids?
- insoluble in water
- Composed of C, H, O
- Carbohydrate are easily converted to fat in body
Where can fat be stored?
Adipose tissue
What do the presence of double bonds in lipids dictate?
type, role, function, health effect
What does the overconsumption of protein lead to?
- Weight control
- Heart disease
- Cancer
- Adult bone loss (osteoporosis)
- Kidney Disease
What does insufficient protein intake lead to?
- Marasmus
- Kwashiorkor
- Wernicke-korsakoff syndrome
- Bone health impacts
What are complementary proteins?
combining plant foods that together contain all the essential amino acids
What makes a high quality protein?
- contain all the essential amino acids
- animal foods contain all the essential amino acids
- plant foods tend to be missing one or more essential amino acids
What is dietary fibre?
- Dietary fibre provides structure in plants
- Cannot be broken down by human enzymes
What are soluble fibres?
Soluble fibres are viscous and can be digested by intestinal bacteria (fermentability). Found in fruits and vegetables.
What are insoluble fibres?
Insoluble fibres are non-viscous and are not digested by intestinal bacteria. Found in grains and vegetables.
What are storage carbohydrates?
glycogen and starch
What are the two monosaccharides?
glucose and fructose
What are the three disaccharides?
sucrose
maltose
lactose
What do nutritional needs depend on?
- Age
- Body size
- Gender
- Genetic traits
- Growth
- Illness
- Lifestyle habits
- Medications
- Pregnancy and lactation
What is energy balance?
- Food in vs energy out
- Need to consider Basal metabolism and Thermogenesis as this burns calories
What does an empty stomach trigger?
- Triggers gastric contractions
- Signals hunger
- Changes in hormones
What is the most satiating macronutrient?
Protein
What is the NHMRC Evidence review ?
- Defining the question
- Planning the evidence search, analysis and reporting
- Searching for evidence
- Selecting evidence
- Checking evidence for bias
- Describing the body of evidence
- Assessing the certainty of evidence
- Presenting results and reporting
What are some of the factors influencing what people eat?
- social
- cultural
- environmental
- socioeconomic
- individual lifestyle
What are the AU dietary guidelines?
- To achieve and maintain a healthy weight, be physically active and choose amounts of nutritious food and drinks to meet your energy needs
- Enjoy a wide variety of nutritious foods from these five groups every day
- Limit intake of foods containing saturated fat, added salt, added sugars and alcohol
- Encourage, support and promote breastfeeding
- Care for your food; prepare and store it safely
What is the recommended carb intake?
45-65% of calories
What is the recommended protein intake?
10-35% of calories
what is a high quality protein?
contain all the essential amino acids
what is the recommended intake of fats?
- 20-35% of calories from fat
- <10% from saturated fat
- <1% trans fats
What are the fat soluble vitamins
ADEK
What is a result of micronutrient deficiency?
- Depletion of tissue reserves
- Decrease blood nutrients
- Insufficient nutrients to cells
- Impaired cellular function
- Physical symptoms
What is a result of micronutrient toxicity?
- saturation of tissue reserves
- increase blood nutrients
- excessive nutrients to cells
- Impaired cellular function
- Physical symptoms
What are vitamins?
- Cannot be synthesised by the body: needed through diet, bacteria, sun etc
- Required for growth, maintenance, reproduction and lactation.
What is bioavailability
Bioavailability is the rate and extent that a nutrient is absorbed and used.
What are vitamin precursors?
Precursors/provitamins are consumed in an inactive form and become active vitamins in the body
What are functions of vitamin A?
- Vision
- Healthy skin
- Cell differentiation
- Reproduction, foetal development, growth and maintenance of bones, teeth, and cell structure
- Beta carotene works as an antioxidant
What is a result of Vit A deficiency?
- Night blindness
- Lowered immune system
- skin keratinisation
What is a result of Vit A toxicity?
- Orange skin
- Fatigue, weakness, severe headache, blurred vision, hair loss and joint pain.
- Severe liver or brain damage
- Birth defects
What are sources of vitamin A?
- Leafy green vegetables
- Orange and yellow vegetables
- Tomatoes
- Fruits (mango, cantaloupe)
- Liver
- Fish oils
- Milk/Eggs
What are the functions of Vitamin D?
- Building and maintaining bones and teeth
- Absorption and utilisation of calcium
- Boost immune system
- Brain and nervous system (dementia and Alzheimer’s)
- May also help decrease certain cancers
What is a result of vitamin D deficiency?
- Inadequate diet : Vegetarianism, lactose intolerance, milk allergy
- Body unable to absorb needed vitamin D
- Limited exposure to sunlight;
- Dark skin
- Cultural practices
- Older people
What is a result of vitamin D deficiency in children?
- Inadequate calcification of bones
- Growth retardation
- Bowed legs
- Enlargement of the ends of long bones
- Deformities of ribs, rachitic rosary of rickets
- Lax muscles (resulting in a protruding abdomen) and muscle spasms
What is a result of vitamin D deficiency in adults?
Osteoporosis and osteomalacia
What are sources of Vitamin D?
- Synthesised in the body from cholesterol
- Sun exposure for 10 minutes a day
Foods: - Fortified milk, butter, margarine
- Tuna, salmon, egg yolks
- Vegans may need a supplement
What are functions of vitamin E?
- Important to red blood cells, muscles and other tissues
- Antioxidant
- Deficiency and toxicity is rare
What are sources of Vitamin E?
- Vegetable oils, salad dressings, whole grain cereals, green leafy vegetables, nuts, seeds, peanut butter and wheat germ, liver and egg yolk
What are functions of vitamin K?
- Important for blood clotting
- Bone health
- Mostly made in intestines by gut bacteria
- Babies born with sterile gut: need vitamin K injection
What is a result of Vitamin K deficiency?
- haemorrhaging
- Secondary deficiencies may occur with use of antibiotics.
What is a result of Vitamin K toxicity?
- No known toxicities
- High doses can decrease the effectiveness of anticlotting medications.
What are sources of Vitamin K?
- Bacterial synthesis in the GI tract,
- Turnip greens
- cauliflower
- spinach,
- liver
- broccoli, kale and cabbage
What are water soluble vitamins?
B group and C
- Absorbed directly into the blood and travel freely
- Very active in body. Several B vitamins form part of coenzymes involved in release of energy
- Participate in metabolism and cell multiplication.
- Can be destroyed by exposure to light, oxidation, cooking, and storage
What are the functions of thiamin/B1?
Helps convert carbohydrates to energy as part of the coenzyme thiamine pyrophosphate (TPP).
What is a result of B1 deficiency?
Fatigue, nausea, depression, nerve damage
What are sources of B1?
Pork, beef, liver, peas, seeds, legumes, whole-grain products, oatmeal, vegemite
What are the functions of riboflavin/B2?
Key to metabolism and red blood cells
What is a result of B2 deficiency?
- Dry, scaly skin
- Sore throat
- Cracks and redness at the corners of the mouth
What are sources of B2?
- Milk, yogurt, cheese, whole-grain breads, green leafy vegetables, meat, and eggs
What are the functions of niacin/B3?
- Involved with energy production
- Helps with skin, nerves and digestive system
What is a result of B3 deficiency?
Rare, but causes: diarrhea, dermatitis, dementia and death
What are sources of B3?
- Meat, poultry, liver, eggs, brown rice, baked potatoes, fish, milk, and whole-grain foods
- The body can make niacin from the amino acid tryptophan in the body
What are the functions of pyridoxine/B6?
Involved in chemical reactions of proteins and amino acids
What is a result of B6 deficiency?
Skin changes, dementia, nervous system disorders and anemia
What are sources of B6?
Lean meats, fish, legumes, green leafy vegetables, raisins, corn, bananas, mangos
What are the functions of cobalamin/B12?
Helps with nervous system, red blood cells and DNA synthesis
What is a result of B12 deficiency?
Nervous system disorders and pernicious anemia (elderly)
What are sources of B12?
- Only found in animal products
- Meat, fish, poultry, eggs, milk products and clams
What is the role of folate?
- Red blood cell formation, DNA synthesis, cell division, helps the body make new cells
- Part of coenzymes
What is a result of folate deficiency?
- Anemia, digestive disorders, Spina Bifida (neural tube defects), heart disease
- Very vulnerable to medications
What is a result of folate toxicity?
- masks B12 deficiency
What are sources of folate?
- Leafy, dark green vegetables
- Vitamin C increase absorption
- Also found in liver, beans, peas, asparagus, oranges, avocados
What are the important populations of folate?
- Additional requirements in women planning/during a pregnancy
What is a folate intervention?
Mandatory folate fortification of wheat flour
What is a role of Vitamin C?
Important to bone health, blood vessel health, cell structure and absorption of iron
What is a result of deficiency with vitamin C?
- Rare, but can cause poor wound healing, frequent infections
- Scurvy
What is a result of toxicity with vitamin C?
Diarrhoea and nausea
What are food sources of Vitamin C?
Melons, berries, tomatoes, potatoes, broccoli, fortified juices, kiwi, mangos, yellow peppers and citrus fruits
What are symptoms of scurvy?
- bleeding gums and loosened teeth
- poor wound healing
- frequent infections
- pinpoint haemorrhages
- fragile bones and joint pain
- rough skin and blotchy bruises
- muscle degeneration & pain
- hysteria and depression
What do binders do to minerals?
- Binders in food can combine chemically with minerals and prevent their absorption.
→ Phytates in legumes and grains.
→ Oxalates in spinach and rhubarb.
what are the major minerals?
Include calcium, chloride, magnesium, phosphorus, potassium, sodium, and sulphur
what are the trace minerals?
Include iron, zinc, iodine, selenium, copper, manganese, fluoride, chromium, molybdenum, arsenic, nickel, silicon, boron and cobalt
What is the role of sodium?
- Helps maintain fluid balance
- Helps transmit nerve impulses
- Influences contraction and relaxation of muscles
What occurs in excess sodium?
- Causes high blood pressure
- May lead to fluid retention
- Role in Osteoporosis
What is the role of potassium?
- Associated with fluid balance
- Low potassium intakes increase blood pressure.
- High potassium intakes prevent and correct hypertension
What is the role of calcium?
- The most abundant mineral
- 99% is stored in the bones
- Required for bone health
- disease prevention
- Hypertension
- Obesity
- Osteoporosis
what is the role of phosphorus?
- Mineralisation of bones and teeth
- Important in energy metabolism & energy transfer part of every cell
what are sources of phosphorus?
Dairy products, meats, poultry, fish, eggs, nuts, legumes, vegetables & grains
What are the roles of iron?
- Oxygen transport (red blood cells)
- Enzymes: most contain iron
- Immune system: fight infection
What is a result of iron deficiency?
- Too little iron= too little oxygen
- Anaemia
- Impaired immunity
- Impaired cognitive function
- Adverse pregnancy outcomes
What are sources of iron?
- Heme iron: animal sources (red meats, liver, poultry & eggs)
- Non-heme iron: plant sources (beans, nuts. Seeds, dried fruits, fortified breads & cereals)
What are roles of zinc?
- Helps make parts of DNA and RNA, manufactures haem for haemoglobin, assists in essential fatty acid metabolism, releases vitamin A from liver stores
- Metabolises carbohydrates and alcohol, synthesises proteins
- Disposes of damaging free radicals
- Involved in growth, development, and immune function
- Affects platelets in blood clotting and wound healing
- Needed to produce the retinal form of vitamin A
- Affects thyroid hormone function
- Influences behaviour and learning
- Taste perception
- Sperm and foetal development
What are symptoms of zinc deficiency?
- Growth retardation
- Delayed sexual maturation
- Impaired immune function
- Hair loss, eye and skin lesions
- Altered taste, loss of appetite
- delayed wound healing.
what are sources of zinc?
Oysters, meat, fish, milk, legumes
What is the role of iodine?
- Essential component of thyroid hormone (regulate metabolism)
- Regulates body temperature, growth, development, metabolic rate, nerve and muscle function, reproduction, and blood cell production.
What is a result of iodine deficiency?
- Impaired intellectual development
- Goitre
- Cretinism
what are sources of iodine?
Iodised salt, sea food, produce from iodine rich soil, fortified products
What are roles of fluoride?
Formation of teeth and bones; helps resist tooth decay
What is an EAR (Estimated Average Requirement) ?
A daily nutrient level estimated to meet the requirements of half the healthy individuals in a particular life stage and gender group.
What is an RDI (Recommended Dietary Intake) ?
The average daily dietary intake level that is sufficient to meet the nutrient requirements of nearly all (97–98 per cent) healthy individuals in a particular life stage and gender group.
What is an AI (Adequate Intake)?
[used when an RDI cannot be determined]
- The average daily nutrient intake level based on observed approximations or estimates of nutrient intake by a group (or groups) of apparently healthy people that are assumed to be adequate.
What is an EER (Estimated Energy Requirement) ?
- The average dietary energy intake that is predicted to maintain energy balance in a healthy adult of defined age, gender, weight, height and level of physical activity, consistent with good health.
- In children and pregnant and lactating women, the EER includes needs associated with the deposition of tissues or the secretion of milk at rates consistent with good health.
What is an UL (Upper Level of Intake) ?
- The highest average daily nutrient intake level likely to pose no adverse health effects to almost all individuals in the general population.
- Above the UL, the risk of adverse effects increases.
What is AMDR (Acceptable Macronutrient Distribution Range) ?
- Estimate of the range of intake for each macronutrient for individuals (%), which would allow for an adequate intake of all the other nutrients whilst maximising general health outcome.
What is an SDT (Suggested Dietary Target) ?
- A daily average intake from food and beverages for certain nutrients that that may help in prevention of chronic disease.
- Average intake may be based on mean/median depending on available data.
What is a dietary assessment?
Collection of information on food/drinks consumed over a specified time that is processed to compute intakes of energy, nutrients and other dietary constituents using food composition tables.
Direct Methods (Retrospective vs prospective)
Explain the difference in methods
Retrospective
- information on foods and beverages already consumed
- Examples: food frequency questionnaire, diet history, 24-hour recall, screeners
Prospective
- all food and beverages recorded at the time of consumption
- Examples: weighted food record, estimated food record 3/7 day diet diary
What is a Food Frequency Questionnaire ?
- a limited checklist of foods and beverages with a frequency response section for subjects to report how often each item was consumed over a specified period of time.
- Semi-quantitative FFQs collect portion size information as standardized portions or as a choice of portion sizes.
What is a 24-hour diet recall ?
- Recorded intake of 24 hours prior to interview
- Includes types of food, amounts and timing
- Estimate total intake of food, beverages, food energy, nutrients and non-nutrient food components consumed by the Australian population, to assess dietary behaviors and the relationship between diet and health.
What is Dietary Scores (Sceening) ?
- Used to measure the frequency of consumption without including information on portion size or dietary behavior
- Not recommended to use when trying to measure precise intake levels
Example: Minimum Dietary Diversity-Women (MDD-W)
What is fertility impacted by?
- Diet
- Smoking, alcohol, drugs
- Exercise behaviours
- Disease and illness
- Body weight
- Chemicals and toxins
How does body weight affect fertility?
- Body fat levels (low and excessive) are linked to infertility in both women and men
- Changes in hormone concentrations
- Small changes in weight (5-10% body weight) towards a healthy weight can greatly improve fertility
What is undernutrition?
Includes being underweight for one’s age, too short for one’s age (stunted), dangerously thin (wasted), and deficient in vitamins and minerals (micronutrient malnutrition).
What is malnutrition?
refers to both undernutrition and overnutrition.
What is Acute undernutrition?
- appears to have the greatest impact on fertility, though is likely to improve with dietary changes towards recommendations for good health.
What is chronic undernutrition?
likely to impact on the baby’s health e.g. low birth weight
What is low sperm count associated with?
- Undernutrition or being overweight
- Abdominal obesity
- Alcohol consumption (heavy/binge)
What improves male fertility?
- Adequate Zinc intake
- Antioxidants
What has a negative impact on fertility for females?
- Saturated (vs trans) fats
- Refined carbohydrates
- Added sugars
- No clear link between caffeine and fertility in humans
- Alcohol (binge/heavy drinker) lowers chance of conception
What has a positive impact on fertility for females?
- Diet containing more vegetable (vs animal) protein
- Low glycemic load
- Antioxidants (reduction of oxidative stress and free radicals)
- Mediterranean dietary patterns
- Dietary fiber, omega-3 (ɷ-3) fatty acids
What lifestyle factors impact fertility?
- Physical activity
- Stress
- Cigarette smoking and drug use
- Environmental toxins
What is pre conception care?
- Set of interventions that are to be provided before pregnancy, to promote the health and well-being of women and couples, as well as to improve the pregnancy and child-health outcomes.
What are the 1000 days of pregnancy?
The first 1000 days includes:
- Pregnancy
- 1st year
- 2nd year
What does each trimester signify?
Trimester 1: weeks 1-12
- Blastocyst implantation, embryo development, placenta formation, organ formation
Trimester 2: weeks 13-27
- Foetus practicing breathing and movement, organ development
Trimester 3: weeks 28-40
- Body and organ growth
- Rapid increase in body fat
Why is the first 1000 days so important?
- Significant growth and development
- Up to 22g growth per day
- Nutrition influences ability to grow, learn and rise out of poverty
- Foundations for optimum health and development across the lifespan are established.
- Physical and mental growth can be stunted for life and can be irreversible if nutrition is deprived
What are Foetal Origins of Adult Disease (FOAD)?
- Risk factors from intrauterine environmental exposures affect the foetus’ development during sensitive periods, and increases the risk of specific diseases in adult life
- Period of ‘developmental plasticity’ → periods where an organism is “plastic” or “sensitive” to its environment
What are the 10 building blocks for nutrition in the first 1000 days?
- Nutritious diet in pregnancy
- Good care in pregnancy
- Exclusive breastfeeding for 6 months
- Nurturing, responsive, care of feeding for babies and toddlers
- Right foods introduced at right times for babies.
- Healthy and nutritious diet for babies and toddlers
- Water and beverages with no added sugars
- Right knowledge and skills for parents to nourish children.
- Consider access to enough nutritious foods
- Societal investments for baby and toddlers
What are the increased pregnancy energy requirements?
- 1st trimester: No additional requirement
- 2nd trimester: Additional 1.4 MJ/day
- 3rd trimester: Additional 1.9 MJ/day
Importance of iron in pregnancy?
- Adequate iron status for women improves conception and reduces early complications in pregnancy.
Impact of iron deficiency on pregnant women?
- Reduced physical performance
- Increased fatigue
- Reduced cognitive performance
- Increased risk of infection & hospitalisation
- Pre-eclampsia & bleeding
- Inhibited lactation
- Greater risk of perinatal mortality & morbidity
Impact of iron deficiency on foetus?
- Spontaneous abortion
- Premature delivery
- Intrauterine foetal death
- Low birth weight
- Hypertension
- Neurologic impairment
Do calcium requirements increase in pregnancy?
No. Absorption of intake increases during pregnancy so intake doesn’t actually need to
Importance of folate in pregnancy?
- Strong evidence for the role of folate in neural tube development in early pregnancy
- Inadequate folate intake linked to birth defects such as spina bifida
- Potential role in male fertility
Importance of iodine in pregnancy?
- Iodine stored in the thyroid and during pregnancy the thyroid is very active, producing about 50% more thyroid hormones.
- Additional iodine is needed to produce enough hormones to support healthy foetal development
- Essential nutrient vital for the healthy development of the brain and nervous system before birth
Risk of foodborne illnesses in pregnancy?
- Listeria
- Type of bacteria
- Found in soft cheeses, sandwich meats, bean sprouts, prepared salad, chilled seafood and pate
- mild symptoms for women
- Can lead to miscarriage, stillbirth or infection of the new born baby - Salmonella
- Most common food poisoning
- Pregnant women at higher risk of severe illness
- Rare cases may trigger miscarriage or long-term complications for the mother
- High risk foods are raw and lightly cooked eggs and egg products
Alcohol and pregnancy
No known safe drinking level for women when pregnant
Caffeine and pregnancy
- Risk of miscarriage and stillbirth
- Pregnant women should limit caffeine intake to less than 200 mg per day
Is there a risk of fish intake on pregnancy?
pregnant women should choose fish with low level of mercury
Impact on foetus
- Impacts brain and nervous system
- May not be noticed until developmental milestones ( walking & talking ) delayed
- Memory, language and attention span can also be impacted
What is the normal weight gain for a woman in pregnancy?
10-14kgs
what does compromised nutrient intake lead to?
Short-term: increased risk of premature birth, low birth weight and other birth complications
Long-term: increased risk for the development of chronic disease later in life
What do low and large birth weights have complications with?
- Low birth weight: <2.5 kilograms (increased mortality and morbidity, growth and brain development issues and chronic disease later in life)
- Large for gestational age: >4.5kilograms (birth complications, increased risk for obesity later in life)
What are the 4 common micronutrient deficiencies?
- Iron
- Vitamin A
- Iodine
- Zinc
What are the causes of micronutrient deficiencies in pregnancy?
- Poverty
- Food Insecurity
- Lack of knowledge/education
- Heavy burden of infectious diseases
- Poor hygiene and sanitation
What are the consequences of micronutrient deficiencies in pregnancy?
Increased maternal morbidly, mortality, poor birth outcomes (low birth weight), neonatal mortality and subsequent childhood malnutrition
What are the concerns surrounding adolescent pregancy?
- Adolescence is a time of rapid growth → higher energy requirement
- higher risk of eclampsia puerperal endometritis, and systemic. infections
- higher risks of low birth weight, preterm delivery and severe neonatal conditions
What are the risks of being overweight in pregnancy?
Increased risk of gestational diabetes mellitus and hypertension
When is screening of gestational diabetes?
Screening in second trimester
What is Foetal alcohol spectrum disorder ?
- Alcohol crosses the placenta
- Can lead to low birth weight, intellectual disability, behavioural problems, distinct facial features, heart defects
What is the Dietary patterns impact on pregnancy ?
Vegetarianism and veganism
- non-haem iron is less well absorbed
- Vegan diet may require Vit B12 supplementation
Other lifestyle factors
- Smoking: increases risk of low birth weight
- Caffeine: decreases iron absorption, increase risk of miscarriage and low birth weight
Why is breastfeeding optimal?
- Best start to life
- Tailored to needs of infants
- optimal source of nutrition for the first six months of an infants life, and with complementary foods up to two years (or, continued until 12 months and beyond) of life
When and how long does breast development occur?
- Takes 3-5 years, commencing at puberty
- Remains inactive until pregnancy
What does the lactating breast consist of physiologically?
- Alveoli, small sacs of milk-secreting cells
- Ducts, transport the milk to the outside via the nipple
- Blood supply (nutrients), lymphatic system (removes waste), nerves (sensitive, hormones)
What does prolactin do in breast milk production?
Prolactin, stimulates production
- Prolactin is important to the next feed.
- The greater suckling, the more prolactin released, thus demand feeding is vital especially in first 6 weeks.
- More prolactin is produced at night, so night time feeding is important for milk production
What does oxytocin do in breast milk production?
Oxytocin, stimulates muscle contraction
- Transports the milk and helps the baby get the milk easily
- Can be triggered by the mother hearing her baby cry or by touching, smelling or seeing her baby
What is the composition of breast milk?
- lower protein than cow’s milks
- half of the energy in milk is derived from fat; reflects the weight status of the mother (concentration) and mother’s diet (composition); more fat in the hind vs fore milk
- micronutrients adequate independent of mother’s intake; low in iron and zinc, though both highly bioavailable
- antimicrobial, anti-inflammatory and immunomodulatory agents
what is colostrum?
- thick yellow fluid produced in the first days after delivery
- low energy and fat, high in protein, minerals and fat-soluble vitamins
- low volume (well hydrated from amniotic fluid and placenta)
- immuno-protective role
How much breastmilk does an infant drink?
- The volume of milk produced matches demand
- Milk intake for an exclusively breastfed infant is approx 1L per day, though changes in line with infant growth requirements
- Milk volume is thought to be consistent across women independent of nutritional status; with the exception of severe protein energy malnutrition